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There are 8 ways to get from St. Louis to West Lafayette by bus, train, car, plane or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  6 h 6 min

  1. Take the bus from St Louis, Mo to Champaign, Il 1364 / ...
  2. Take the bus from University of Illinois - Champaign to Lafayette, IN

$54 - $105

7 alternative options

Bus via West Lafayette, IN - Purdue Memorial Union  •  6 h 56 min

  1. Take the bus from St Louis, Mo to Champaign, Il 1364 / ...
  2. Take the bus from Champaign, IL -UIUC to West Lafayette, IN - Purdue Memorial Union

$54 - $105

Train  •  9 h 37 min

  1. Take the train from St. Louis Gateway Station to Chicago Union Station Lincoln Service / ...
  2. Take the train from Chicago Union Station to Lafayette Amtrak Station Cardinal / ...

$81 - $203

Drive  •  4 h 42 min

  1. Drive from St. Louis to West Lafayette 280.5 miles

$27 - $40

Fly to Indianapolis, shuttle  •  7 h 1 min

  1. Fly from St. Louis (STL) to Indianapolis (IND) STL - IND
  2. Take a shuttle bus from Indianapolis International Airport to Lafayette, IN

$180 - $830

Fly to Chicago O'Hare, shuttle  •  6 h

  1. Fly from St. Louis (STL) to Chicago O'Hare (ORD) STL - ORD
  2. Take a shuttle bus from Chicago, IL - O'Hare Intl Airport to Lafayette, IN

$148 - $302

Fly to Chicago Midway, train  •  7 h 16 min

  1. Fly from St. Louis (STL) to Chicago Midway (MDW) STL - MDW
  2. Take the train from Chicago Union Station to Lafayette Amtrak Station

$154 - $382

Fly to Decatur, bus  •  7 h 31 min

  1. Fly from St. Louis (STL) to Decatur (DEC) STL - DEC
  2. Take the bus from Rs Decatur Il, Il to Champaign, Il
  3. Take the bus from University of Illinois - Champaign to Lafayette, IN

$164 - $572

Questions & Answers

The cheapest way to get from St. Louis to West Lafayette is to drive which costs $27 - $40 and takes 4 h 42 min.

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The quickest way to get from St. Louis to West Lafayette is to drive which costs $27 - $40 and takes 4 h 42 min.

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No, there is no direct bus from St. Louis to West Lafayette. However, there are services departing from St Louis, Mo and arriving at Lafayette, IN via Illinois Terminal and University of Illinois - Champaign. The journey, including transfers, takes approximately 6 h 6 min.

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No, there is no direct train from St. Louis station to West Lafayette station. However, there are services departing from St. Louis Gateway Station and arriving at Lafayette Amtrak Station via Chicago Union Station. The journey, including transfers, takes approximately 9 h 37 min.

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The distance between St. Louis and West Lafayette is 216 miles. The road distance is 280.5 miles.

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The best way to get from St. Louis to West Lafayette without a car is to bus which takes 6 h 6 min and costs $50 - $110.

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It takes approximately 6 h 6 min to get from St. Louis to West Lafayette, including transfers.

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St. Louis to West Lafayette bus services, operated by Greyhound USA, depart from St Louis, Mo station.

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St. Louis to West Lafayette train services, operated by Amtrak, arrive at St. Louis Gateway Station.

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The best way to get from St. Louis to West Lafayette is to bus which takes 6 h 6 min and costs $50 - $110. Alternatively, you can train, which costs $80 - $210 and takes 9 h 37 min.

Mode details

Map of how to get from St. Louis to West Lafayette.
Launch map view
  • Distance: 216.1 miles
  • Duration: 6 h 6 min

What companies run services between St. Louis, MO, USA and West Lafayette, IN, USA?

You can take a bus from St. Louis to West Lafayette via Champaign, Il, Illinois Terminal, Illini Union, and University of Illinois - Champaign in around 6 h 6 min. Alternatively, you can take a train from St. Louis to West Lafayette via Chicago Union Station in around 9 h 37 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from St. Louis to Indianapolis via Chicago Midway
Ave. Duration
3 h 22 min
When
Wednesday, Thursday, Saturday and Sunday
Estimated price
$160 - $750
Flights from St. Louis to Indianapolis via Kansas City
Ave. Duration
4 h 1 min
When
Monday to Friday
Estimated price
$190 - $800
Flights from St. Louis to Indianapolis via Atlanta
Ave. Duration
4 h 5 min
When
Wednesday, Thursday and Friday
Estimated price
$210 - $850
Flights from St. Louis to Chicago Midway
Ave. Duration
1 h 5 min
When
Every day
Estimated price
$160 - $550
United Airlines
Website
united.com
Flights from St. Louis to Indianapolis via Chicago O'Hare
Ave. Duration
3 h 36 min
When
Every day
Estimated price
$170 - $850
Flights from St. Louis to Chicago O'Hare
Ave. Duration
1 h 25 min
When
Every day
Estimated price
$120 - $650
American Airlines
Website
aa.com
Flights from St. Louis to Indianapolis via Chicago O'Hare
Ave. Duration
3 h 49 min
When
Every day
Estimated price
$150 - $800
Flights from St. Louis to Chicago O'Hare
Ave. Duration
1 h 25 min
When
Every day
Estimated price
$120 - $550
Delta
Website
delta.com
Flights from St. Louis to Indianapolis via Detroit
Ave. Duration
3 h 59 min
When
Every day
Estimated price
$160 - $850
Flights from St. Louis to Indianapolis via Atlanta
Ave. Duration
4 h 6 min
When
Every day
Estimated price
$180 - $850
Cape Air
Website
capeair.com
Flights from St. Louis to Chicago O'Hare via Decatur
Ave. Duration
3 h 3 min
When
Thursday and Friday
Estimated price
$130 - $380
Flights from St. Louis to Decatur
Ave. Duration
51 min
When
Every day
Estimated price
$100 - $470
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from St. Louis Gateway Station to Chicago Union Station
Ave. Duration
5 h 40 min
Frequency
Every 4 hours
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$90 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Train from Chicago Union Station to Lafayette Amtrak Station
Ave. Duration
2 h 57 min
Frequency
Once daily
Estimated price
$30 - $75
Website
amtrak.com
Coach Seat
$30 - $50
Flexi Coach Seat
$55 - $85
Business Coach Seat
$50 - $75
Room
$160 - $240
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from St Louis, Mo to Champaign, Il
Ave. Duration
3 h
Frequency
5 times a day
Estimated price
$23 - $55
Website
greyhound.com
Economy
$23 - $35
Flexible
$40 - $55
Bus from Rs Decatur Il, Il to Champaign, Il
Ave. Duration
50 min
Frequency
Once daily
Estimated price
$11 - $24
Website
greyhound.com
Economy
$11 - $16
Flexible
$19 - $24
Express Air Coach
Website
expressaircoach.com
Bus from University of Illinois - Champaign to Lafayette, IN
Ave. Duration
2 h
Frequency
Every 4 hours
Estimated price
$30 - $50
Schedules at
expressaircoach.com
Bus from Champaign, IL -UIUC to West Lafayette, IN - Purdue Memorial Union
Ave. Duration
2 h 50 min
Frequency
4 times a week
Estimated price
$30 - $50
Schedules at
expressaircoach.com
Lafayette Limo
Phone
+1(765)4973828
Website
lafayettelimo.com
Shuttle from Indianapolis International Airport to Lafayette, IN
Ave. Duration
1 h 35 min
Frequency
Every 3 hours
Estimated price
$27
Schedules at
lafayettelimo.com
Shuttle from Chicago, IL - O'Hare Intl Airport to Lafayette, IN
Ave. Duration
2 h 10 min
Frequency
3 times a day
Estimated price
$60
Schedules at
lafayettelimo.com
Book at
lafayettelimo.ontimereservations.com

Want to know more about travelling around United States

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More Questions & Answers

There is no direct flight from St. Louis Airport to Indianapolis Airport. The quickest flight takes 2 h 50 min and has one stopover.

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St. Louis to West Lafayette bus services, operated by Express Air Coach, arrive at Lafayette, IN station.

More details

West Lafayette is 1 h ahead of St. Louis. It is currently 11:23 PM in St. Louis and 12:23 AM in West Lafayette.

St. Louis to West Lafayette train services, operated by Amtrak, arrive at Lafayette Amtrak Station.

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Yes, the driving distance between St. Louis to West Lafayette is 280 miles. It takes approximately 4 h 42 min to drive from St. Louis to West Lafayette.

Get driving directions

American Airlines, United Airlines, Delta and Southwest Airlines offer flights from St. Louis Airport to Indianapolis Airport.

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Book your St. Louis to West Lafayette train tickets online with Rome2rio.

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There are 28+ hotels available in West Lafayette. Prices start at $62 USD per night.

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The best way to get from St. Louis to St. Louis Airport is to train which takes 31 min and costs $3.

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