There are 6 ways to get from St. Louis to West Lafayette by bus, car, plane or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  6 h 8 min

  1. Take the bus from St Louis, Mo to Champaign, Il 1364 / ...
  2. Take the bus from University of Illinois - Champaign to Lafayette, IN

$54 - $105

5 alternative options

Drive  •  4 h 42 min

  1. Drive from St. Louis to West Lafayette 280.5 miles

$27 - $40

Fly to Indianapolis  •  7 h 10 min

  1. Fly from St. Louis (STL) to Indianapolis (IND) STL - IND

$179 - $829

Fly to Chicago O'Hare, shuttle  •  6 h 30 min

  1. Fly from St. Louis (STL) to Chicago O'Hare (ORD) STL - ORD
  2. Take a shuttle bus from Chicago O'Hare T5 to Lafayette, IN

$158 - $317

Fly to Chicago Midway, shuttle  •  6 h 28 min

  1. Fly from St. Louis (STL) to Chicago Midway (MDW) STL - MDW
  2. Take a shuttle bus from Chicago O'Hare T5 to Lafayette, IN

$196 - $382

Fly to Decatur, bus  •  7 h 33 min

  1. Fly from St. Louis (STL) to Decatur (DEC) STL - DEC
  2. Take the bus from Rs Decatur Il, Il to Champaign, Il
  3. Take the bus from University of Illinois - Champaign to Lafayette, IN

$164 - $572

Questions & Answers

The cheapest way to get from St. Louis to West Lafayette is to drive which costs $27 - $40 and takes 4 h 42 min.

More details

The quickest way to get from St. Louis to West Lafayette is to drive which takes 4 h 42 min and costs $27 - $40.

More details

The distance between St. Louis and West Lafayette is 346 km. The road distance is 449 km.

Get driving directions

It takes approximately 6 h 8 min to get from St. Louis to West Lafayette, including transfers.

More details

No, there is no direct bus from St. Louis to West Lafayette. However, there are services departing from St Louis, Mo and arriving at Lafayette, IN via Illinois Terminal and University of Illinois - Champaign. The journey, including transfers, takes approximately 6 h 8 min.

More details

What companies run services between St. Louis, MO, USA and West Lafayette, IN, USA?

You can take a bus from St. Louis to West Lafayette via Champaign, Il, Illinois Terminal, Illini Union, and University of Illinois - Champaign in around 6 h 8 min. Alternatively, Southwest Airlines, American Airlines and two other airlines fly from St. Louis to West Lafayette hourly.

Airlines
Southwest Airlines
Website
southwest.com
Flights from St. Louis to Indianapolis via Chicago Midway
Ave. Duration
3 h 42 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$160 - $750
Flights from St. Louis to Indianapolis via Kansas City
Ave. Duration
3 h 45 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$190 - $800
Flights from St. Louis to Indianapolis via Atlanta
Ave. Duration
4 h 30 min
When
Sunday
Estimated price
$210 - $850
Flights from St. Louis to Indianapolis via Dallas
Ave. Duration
4 h 35 min
When
Sunday
Estimated price
$240 - $950
Flights from St. Louis to Chicago Midway
Ave. Duration
1 h 3 min
When
Every day
Estimated price
$160 - $550
United Airlines
Website
united.com
Flights from St. Louis to Indianapolis via Chicago O'Hare
Ave. Duration
3 h 55 min
When
Every day
Estimated price
$170 - $850
Flights from St. Louis to Chicago O'Hare
Ave. Duration
1 h 22 min
When
Every day
Estimated price
$120 - $650
American Airlines
Website
aa.com
Flights from St. Louis to Indianapolis via Chicago O'Hare
Ave. Duration
3 h 24 min
When
Every day
Estimated price
$150 - $800
Flights from St. Louis to Indianapolis via Charlotte
Ave. Duration
4 h 30 min
When
Every day
Estimated price
$200 - $900
Flights from St. Louis to Chicago O'Hare
Ave. Duration
1 h 21 min
When
Every day
Estimated price
$120 - $550
Delta
Website
delta.com
Flights from St. Louis to Indianapolis via Detroit
Ave. Duration
3 h 57 min
When
Every day
Estimated price
$160 - $850
Flights from St. Louis to Indianapolis via Atlanta
Ave. Duration
4 h 19 min
When
Every day
Estimated price
$180 - $850
Cape Air
Website
capeair.com
Flights from St. Louis to Decatur
Ave. Duration
51 min
When
Every day
Estimated price
$100 - $470
Bus operators
Greyhound USA
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from St Louis, Mo to Champaign, Il
Ave. Duration
3 h
Frequency
Hourly
Estimated price
$23 - $55
Website
greyhound.com
Economy
$23 - $35
Flexible
$40 - $55
Bus from Rs Decatur Il, Il to Champaign, Il
Ave. Duration
50 min
Frequency
Every 3 hours
Estimated price
$11 - $24
Website
greyhound.com
Economy
$11 - $16
Flexible
$19 - $24
Express Air Coach
Website
expressaircoach.com
Bus from University of Illinois - Champaign to Lafayette, IN
Ave. Duration
2 h
Frequency
Every 4 hours
Estimated price
$30 - $50
Schedules at
expressaircoach.com
Lafayette Limo
Phone
+1(765)4973828
Website
lafayettelimo.com
Shuttle from Chicago O'Hare T5 to Lafayette, IN
Ave. Duration
2 h 10 min
Frequency
3 times a day
Estimated price
$60
Schedules at
lafayettelimo.com
Book at
lafayettelimo.ontimereservations.com

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