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How to get fromSt. Louis to Waukeeby bus (Greyhound), car, plane, or train

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There are 5 ways to get from St. Louis to Waukee by bus (Greyhound), car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus (Greyhound)

    best
    1. Take the bus from St Louis Bus Station to Des Moinesbus bus Greyhound US0153S
    8h 57m
    $95–164

  2. Drive 346.5 mi

    cheapest
    1. Drive from St. Louis to Waukeecar car 346.5 mi
    6h 55m
    $64–92

  3. Fly Lambert–St. Louis International Airport to Des Moines

    1. Fly from Lambert–St. Louis International Airport (STL) to Des Moines (DSM)plane plane STL - DSM
    5h 39m
    $172–802

  4. Train to Abraham Lincoln Capital Airport, fly to Des Moines

    1. Take the train from St. Louis to Springfieldtrain train
    2. Fly from Abraham Lincoln Capital Airport (SPI) to Des Moines (DSM)plane plane SPI - DSM
    7h 3m
    $176–676

  5. Fly Lambert–St. Louis International Airport to Fort Dodge Municipal Airport, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Fort Dodge Municipal Airport (FOD)plane plane STL - FOD
    2. Drive from Fort Dodge Municipal Airport (FOD) to Waukeecar car
    7h 40m
    $96–484

Lambert–St. Louis International Airport (STL) to Des Moines (DSM) flights

Calendar111Weekly Planes
Duration4h 56mAverage Duration
Ticket$130Cheapest Price
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Comparing Your Travel Options

Map of how to get from St. Louis to Waukee.ExpandLaunch map view
  • Distance: 432.6 mi
  • Duration: 8h 57m

What companies run services between St. Louis, MO, USA and Waukee, IA, USA?

Greyhound USA operates a bus from St Louis Bus Station to Des Moines once daily. Tickets cost $60–120 and the journey takes 8h 30m. Alternatively, Southwest Airlines, American Airlines, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Des Moines (DSM) hourly.

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