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How to get fromSt. Louis to Twispby plane, bus, train or car

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There are 5 ways to get from St. Louis to Twisp by plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Wenatchee, bus

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Wenatchee (EAT)planeSTL - EAT
    2. Take the bus from Wenatchee Columbia Station to Paterosbus
    3. Take the bus from Pateros, WA to Twisp, WA - Canyon & Hwy 20bus
    13h 53m
    $214–880

  2. Train, bus

    cheapest
    1. Take the train from St. Louis to Chicago Union Stationtrain
    2. Take the train from Chicago Union Station to Wenatchee Amtraktrain
    3. Take the bus from Wenatchee Columbia Station to Paterosbus
    4. Take the bus from Pateros, WA to Twisp, WA - Canyon & Hwy 20bus
    2d 3h
    $211–520

  3. Drive 1,975.4 mi

    1. Drive from St. Louis to Twispcar1,975.4 mi
    31h 53m
    $361–521

  4. Fly to Seattle-Tacoma International Airport, train, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Seattle-Tacoma International Airport (SEA)planeSTL - SEA
    2. Take the train from Seattle to Wenatchee Amtraktrain
    3. Take the bus from Wenatchee Columbia Station to Paterosbus
    4. Take the bus from Pateros, WA to Twisp, WA - Canyon & Hwy 20bus
    15h 17m
    $266–1,146

  5. Fly to Spokane International Airport, train, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Spokane International Airport (GEG)planeSTL - GEG
    2. Take the train from Spokane to Wenatchee Amtraktrain
    3. Take the bus from Wenatchee Columbia Station to Paterosbus
    4. Take the bus from Pateros, WA to Twisp, WA - Canyon & Hwy 20bus
    16h 21m
    $220–888

Lambert–St. Louis International Airport (STL) to Wenatchee (EAT) flights

Calendar29Weekly Planes
Duration8h 54mAverage Duration
Ticket$189Cheapest Price
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Questions & Answers

What companies run services between St. Louis, MO, USA and Twisp, WA, USA?

There is no direct connection from St. Louis to Twisp. However, you can take the train to LAMBERT AIRPORT TERMINAL #1 station, walk to Lambert–St. Louis International Airport (STL) airport, fly to Wenatchee (EAT), walk to 1 Pangborn Drive, take the line 15 bus to Wenatchee Columbia Station, take the bus to Pateros, walk to Pateros, WA, then take the bus to Twisp, WA - Canyon & Hwy 20. Alternatively, you can take a train from St. Louis to Twisp, WA - Canyon & Hwy 20 via Chicago Union Station, Wenatchee Amtrak, Wenatchee Columbia Station, Pateros, and Pateros, WA in around 2d 3h.

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