There are 7 ways to get from St. Louis to Silicon Valley by plane, bus (Greyhound, Flixbus), train, bus, subway, car, or train (Amtrak)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to San Francisco International Airport
best- Fly from Lambert–St. Louis International Airport (STL) to San Francisco International Airport (SFO)STL - SFO
6h 55m$144–620Bus
- Take the bus from St Louis Bus Station to Los Angeles Union StationGreyhound US1210
- Take the bus from Los Angeles Union Station to Redwood City StationFlixBus N2002
47h 44m$168–481Train, bus, BART
- Take the train from St. Louis to Springfield
- Take the bus from Springfield to Galesburg Amtrak Station
- Take the train from Galesburg Amtrak Station to Richmond
- Take the subway from Richmond to Millbrae
2d 10hDrive 2,073.3 mi
- Drive from St. Louis to Silicon Valley2,073.3 mi
32h 12m$379–547Fly to Norman Y. Mineta San José International Airport
- Fly from Lambert–St. Louis International Airport (STL) to Norman Y. Mineta San José International Airport (SJC)STL - SJC
8h 30m$230–962Fly to Oakland International Airport, Caltrain
- Fly from Lambert–St. Louis International Airport (STL) to Oakland International Airport (OAK)STL - OAK
- Take the train from San Francisco Caltrain Southbound to Palo Alto Caltrain Southbound
9h 26m$226–972Train (Amtrak)
- Take the train from St. Louis to Los AngelesTexas Eagle
- Take the train from Los Angeles to San JoseCoast Starlight
2d 23h$273–811
St. Louis to Silicon Valley by bus
Questions & Answers
The cheapest way to get from St. Louis to Silicon Valley is to bus which costs $160 - $490 and takes 47h 44m.
The fastest way to get from St. Louis to Silicon Valley is to fly which takes 6h 55m and costs $140 - $650.
No, there is no direct bus from St. Louis station to Silicon Valley. However, there are services departing from St Louis Bus Station and arriving at Palo Alto Transit Ctr-Bay 1 via Los Angeles Union Station and Redwood City Caltrain-Lane A. The journey, including transfers, takes approximately 47h 44m.
No, there is no direct train from St. Louis to Silicon Valley. However, there are services departing from St. Louis and arriving at Palo Alto Caltrain Northbound via Los Angeles and San Jose Diridon Caltrain Northbound. The journey, including transfers, takes approximately 2 days 23h.
The distance between St. Louis and Silicon Valley is 1775 miles. The road distance is 2085.4 miles.
The best way to get from St. Louis to Silicon Valley without a car is to bus which takes 47h 44m and costs $160 - $490.
It takes approximately 6h 55m to get from St. Louis to Silicon Valley, including transfers.
St. Louis to Silicon Valley bus services, operated by Greyhound USA, depart from St Louis Bus Station.
St. Louis to Silicon Valley train services, operated by Amtrak, depart from St. Louis station.
The best way to get from St. Louis to Silicon Valley is to fly which takes 6h 55m and costs $140 - $650. Alternatively, you can bus, which costs $160 - $490 and takes 47h 44m, you could also train, which costs $270 - $850 and takes 2 days 23h.
What companies run services between St. Louis, MO, USA and Silicon Valley, CA, USA?
United Airlines and Southwest Airlines fly from Lambert–St. Louis International Airport (STL) to San Francisco International Airport (SFO) every 3 hours. Alternatively, you can take a bus from St Louis Bus Station to Palo Alto Transit Ctr-Bay 1 via Los Angeles Union Station, Redwood City Station, and Redwood City Caltrain-Lane A in around 47h 44m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to San Francisco International Airport
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $130–600
Flights from Lambert–St. Louis International Airport to San Francisco International Airport via Denver
- Ave. Duration
- 6h 11m
- When
- Monday to Saturday
- Estimated price
- $130–600
Flights from Lambert–St. Louis International Airport to San Francisco International Airport via Las Vegas
- Ave. Duration
- 6h 10m
- When
- Monday to Friday
- Estimated price
- $130–600
Flights from Lambert–St. Louis International Airport to San Francisco International Airport via Phoenix
- Ave. Duration
- 6h 27m
- When
- Monday to Saturday
- Estimated price
- $140–650
Flights from Lambert–St. Louis International Airport to San Francisco International Airport via Los Angeles
- Ave. Duration
- 6h 30m
- When
- Sunday
- Estimated price
- $140–650
Flights from Lambert–St. Louis International Airport to Norman Y. Mineta San José International Airport via Denver
- Ave. Duration
- 6h 1m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $220–950
Flights from Lambert–St. Louis International Airport to Norman Y. Mineta San José International Airport via Las Vegas
- Ave. Duration
- 6h 22m
- When
- Every day
- Estimated price
- $220–1,000
Flights from Lambert–St. Louis International Airport to Norman Y. Mineta San José International Airport via Phoenix
- Ave. Duration
- 6h 32m
- When
- Monday, Friday, and Sunday
- Estimated price
- $230–1,000
Flights from Lambert–St. Louis International Airport to Norman Y. Mineta San José International Airport via San Diego
- Ave. Duration
- 6h 25m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $240–1,100
Flights from Lambert–St. Louis International Airport to Norman Y. Mineta San José International Airport via Los Angeles
- Ave. Duration
- 6h 32m
- When
- Monday, Tuesday, Wednesday, and Sunday
- Estimated price
- $230–1,000
Flights from Lambert–St. Louis International Airport to Oakland International Airport via Denver
- Ave. Duration
- 6h 7m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $210–950
Flights from Lambert–St. Louis International Airport to Oakland International Airport via Kansas City
- Ave. Duration
- 6h 5m
- When
- Monday, Tuesday, Wednesday, and Sunday
- Estimated price
- $210–950
Flights from Lambert–St. Louis International Airport to Oakland International Airport via Las Vegas
- Ave. Duration
- 6h 13m
- When
- Monday, Tuesday, Wednesday, Friday, Saturday, and Sunday
- Estimated price
- $210–950
Flights from Lambert–St. Louis International Airport to Oakland International Airport via Phoenix
- Ave. Duration
- 6h 25m
- When
- Every day
- Estimated price
- $220–1,000
Flights from Lambert–St. Louis International Airport to Oakland International Airport via Los Angeles
- Ave. Duration
- 6h 33m
- When
- Monday, Friday, Saturday, and Sunday
- Estimated price
- $230–1,000
Flights from Lambert–St. Louis International Airport to Oakland International Airport via Burbank
- Ave. Duration
- 6h 35m
- When
- Tuesday to Friday
- Estimated price
- $220–1,000
- Website
- united.com
Flights from Lambert–St. Louis International Airport to San Francisco International Airport
- Ave. Duration
- 4h 38m
- When
- Every day
- Estimated price
- $130–600
Flights from Lambert–St. Louis International Airport to San Francisco International Airport via Denver
- Ave. Duration
- 6h 14m
- When
- Every day
- Estimated price
- $130–600
Flights from Lambert–St. Louis International Airport to Norman Y. Mineta San José International Airport via Denver
- Ave. Duration
- 6h 21m
- When
- Every day
- Estimated price
- $220–950
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Norman Y. Mineta San José International Airport via Salt Lake City
- Ave. Duration
- 6h 32m
- When
- Every day
- Estimated price
- $220–950
Flights from Lambert–St. Louis International Airport to Oakland International Airport via Salt Lake City
- Ave. Duration
- 6h 38m
- When
- Every day
- Estimated price
- $210–950
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from St. Louis to Springfield
- Ave. Duration
- 1h 38m
- Frequency
- 5 times a day
- Estimated price
- $18–55
- Website
- https://www.amtrak.com/home.html
Train from Galesburg Amtrak Station to Richmond
- Ave. Duration
- 2d 2h
- Frequency
- Once daily
- Estimated price
- $180–600
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $180–550
- Coach Seat short notice purchase
- $280–600
- Business - advance purchase
- $390–1,500
- Business Class
- $500–1,300
Train from St. Louis to Los Angeles
- Ave. Duration
- 2d 11h
- Frequency
- 3 times a week
- Estimated price
- $180–650
- Website
- https://www.amtrak.com/home.html
Train from Los Angeles to San Jose
- Ave. Duration
- 9h 55m
- Frequency
- Once daily
- Estimated price
- $80–160
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-510-464-6000
- Website
- bart.gov
Subway from Richmond to Millbrae
- Ave. Duration
- 1h 16m
- Frequency
- Every 30 minutes
- Estimated price
- $12–15
- Website
- https://www.bart.gov
- Phone
- +1 800-660-4287
- Website
- caltrain.com
Train from San Francisco Caltrain Southbound to Palo Alto Caltrain Southbound
- Ave. Duration
- 49 min
- Frequency
- Every 30 minutes
- Estimated price
- $7–9
- Website
- https://www.caltrain.com
- Schedules at
- https://www.caltrain.com/?active_tab=route_explorer_tab
- One-way Adult
- $7–9
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from St Louis Bus Station to Los Angeles Union Station
- Ave. Duration
- 38h 45m
- Frequency
- Twice daily
- Estimated price
- $120–390
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Los Angeles Union Station to Redwood City Station
- Ave. Duration
- 7h 20m
- Frequency
- Once daily
- Estimated price
- $45–95
- Schedules at
- flixbus.com
- Adult
- $45–95
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Springfield to Galesburg Amtrak Station
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Website
- https://www.amtrak.com/home.html
Want to know more about travelling around United States
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More Questions & Answers
St. Louis to Silicon Valley bus services, operated by Greyhound USA, arrive at Los Angeles Union Station.
St. Louis to Silicon Valley train services, operated by Amtrak, arrive at Los Angeles station.
Yes, the driving distance between St. Louis to Silicon Valley is 2085 miles. It takes approximately 32h 12m to drive from St. Louis to Silicon Valley.
There are 578+ hotels available in Silicon Valley.


















