There are 3 ways to get from St. Louis to Sikeston by bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  2 h 45 min

  1. Take the bus from St Louis, Mo to Sikeston, Mo 1138

$20 - $50

2 alternative options

Drive  •  2 h 25 min

  1. Drive from St. Louis to Sikeston 146.3 miles

$14 - $21

Fly, bus  •  4 h 54 min

  1. Fly from St. Louis (STL) to Marion (MWA) STL - MWA
  2. Take the bus from Marion, Il to Sikeston, Mo

$59 - $129

What companies run services between St. Louis, MO, USA and Sikeston, MO, USA?

Greyhound USA operates a bus from St. Louis to Sikeston every 4 hours. Tickets cost $20 - $50 and the journey takes 2 h 45 min.

Airlines
Cape Air
Website
capeair.com
Flights from St. Louis to Marion
Ave. Duration
48 min
When
Every day
Estimated price
$29 - $100
Bus operators
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from St Louis, Mo to Sikeston, Mo
Ave. Duration
2 h 45 min
Frequency
Every 4 hours
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $35
Flexible
$35 - $50
Bus from Marion, Il to Sikeston, Mo
Ave. Duration
1 h 30 min
Frequency
Every 2 hours
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$25 - $35

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Questions & Answers

How far is it from St. Louis to Sikeston?

The distance between St. Louis and Sikeston is 202 km. The road distance is 234 km.

What is the cheapest way to get from St. Louis to Sikeston?

The cheapest way to get from St. Louis to Sikeston is to drive which costs $14 - $21 and takes 2 h 25 min.

What is the fastest way to get from St. Louis to Sikeston?

The quickest way to get from St. Louis to Sikeston is to drive which takes 2 h 25 min and costs $14 - $21.

Is there a direct bus between St. Louis and Sikeston?

Yes, there is a direct bus departing from St Louis, Mo and arriving at Sikeston, Mo. Services depart every four hours, and operate every day. The journey takes approximately 2 h 45 min.

How long does it take to get from St. Louis to Sikeston?

The bus from St Louis, Mo to Sikeston, Mo takes 2 h 45 min including transfers and departs every four hours.