There are 2 ways to get from St. Louis to Sikeston by bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  2 h 45 min

  1. Take the bus from St Louis, Mo to Sikeston, Mo 1138

$20 - $50

1 alternative option

Drive  •  2 h 25 min

  1. Drive from St. Louis to Sikeston 146.3 miles

$14 - $21

Questions & Answers

Yes, there is a direct bus departing from St Louis, Mo and arriving at Sikeston, Mo. Services depart every four hours, and operate every day. The journey takes approximately 2 h 45 min.

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The distance between St. Louis and Sikeston is 126 miles. The road distance is 146.3 miles.

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The best way to get from St. Louis to Sikeston without a car is to bus which takes 2 h 45 min and costs .

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The bus from St Louis, Mo to Sikeston, Mo takes 2 h 45 min including transfers and departs every four hours.

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St. Louis to Sikeston bus services, operated by Greyhound USA, depart from St Louis, Mo station.

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St. Louis to Sikeston bus services, operated by Greyhound USA, arrive at Sikeston, Mo station.

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Yes, the driving distance between St. Louis to Sikeston is 146 miles. It takes approximately 2 h 25 min to drive from St. Louis to Sikeston.

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Book your St. Louis to Sikeston bus tickets online with Greyhound.

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There are 12+ hotels available in Sikeston. Prices start at $51 USD per night.

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Map of how to get from St. Louis to Sikeston.
Launch map view
  • Distance: 126.2 miles
  • Duration: 2 h 45 min

What companies run services between St. Louis, MO, USA and Sikeston, MO, USA?

Greyhound USA operates a bus from St. Louis to Sikeston every 4 hours. Tickets cost $20 - $50 and the journey takes 2 h 45 min.

Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from St Louis, Mo to Sikeston, Mo
Ave. Duration
2 h 45 min
Frequency
Every 4 hours
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $35
Flexible
$35 - $50

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