There are 3 ways to get from St. Louis to Sikeston by bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  2 h 45 min

  1. Take the bus from St Louis, Mo to Sikeston, Mo 1138

$20 - $50

2 alternative options

Drive  •  2 h 25 min

  1. Drive from St. Louis to Sikeston 146.3 miles

$14 - $21

Fly, bus  •  4 h 55 min

  1. Fly from St. Louis (STL) to Marion (MWA) STL - MWA
  2. Take the bus from Marion, Il to Sikeston, Mo

$60 - $130

Questions & Answers

The cheapest way to get from St. Louis to Sikeston is to drive which costs $14 - $21 and takes 2 h 25 min.

More details

The quickest way to get from St. Louis to Sikeston is to drive which costs $14 - $21 and takes 2 h 25 min.

More details

The distance between St. Louis and Sikeston is 126 miles. The road distance is 146.3 miles.

Get driving directions

The bus from St Louis, Mo to Sikeston, Mo takes 2 h 45 min including transfers and departs every four hours.

More details

Yes, there is a direct bus departing from St Louis, Mo and arriving at Sikeston, Mo. Services depart every four hours, and operate every day. The journey takes approximately 2 h 45 min.

More details

What companies run services between St. Louis, MO, USA and Sikeston, MO, USA?

Greyhound USA operates a bus from St. Louis to Sikeston every 4 hours. Tickets cost $20 - $50 and the journey takes 2 h 45 min.

Airlines
Cape Air
Website
capeair.com
Flights from St. Louis to Marion
Ave. Duration
48 min
When
Every day
Estimated price
$29 - $100
Bus operators
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from St Louis, Mo to Sikeston, Mo
Ave. Duration
2 h 45 min
Frequency
Every 4 hours
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $35
Flexible
$35 - $50
Bus from Marion, Il to Sikeston, Mo
Ave. Duration
1 h 30 min
Frequency
Every 2 hours
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$25 - $35

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