There are 4 ways to get from St. Louis to Shepherdsville by bus (Greyhound), car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from St Louis Bus Station to Evansville Bus Stationbus Greyhound US0185
- Take the bus from Evansville, IN to Louisville, KYbus Evansville
7h 14m$117–174Drive 279.3 mi
cheapest- Drive from St. Louis to Shepherdsvillecar 279.3 mi
4h 38m$51–74Fly to Louisville International Airport
- Fly from Lambert–St. Louis International Airport (STL) to Louisville International Airport (SDF)plane STL - SDF
5h 4m$158–812Fly to Blue Grass Airport, drive
- Fly from Lambert–St. Louis International Airport (STL) to Blue Grass Airport (LEX)plane STL - LEX
- Drive from Lexington-Airport-LEX to Shepherdsvillecar
6h 48m$216–1,222
Lambert–St. Louis International Airport (STL) to Louisville International Airport (SDF) flights
Questions & Answers
The cheapest way to get from St. Louis to Shepherdsville is to drive which costs $50 - $75 and takes 4h 38m.
The fastest way to get from St. Louis to Shepherdsville is to drive which takes 4h 38m and costs $50 - $75.
The distance between St. Louis and Shepherdsville is 306 miles. The road distance is 280.9 miles.
The best way to get from St. Louis to Shepherdsville without a car is to bus which takes 7h 14m and costs $110 - $180.
It takes approximately 7h 14m to get from St. Louis to Shepherdsville, including transfers.
The best way to get from St. Louis to Shepherdsville is to bus which takes 7h 14m and costs $110 - $180. Alternatively, you can fly, which costs $150 - $850 and takes 5h 4m.
Shepherdsville is 1h ahead of St. Louis. It is currently 4:34 PM in St. Louis and 5:34 PM in Shepherdsville.
Yes, the driving distance between St. Louis to Shepherdsville is 281 miles. It takes approximately 4h 38m to drive from St. Louis to Shepherdsville.
There are 23+ hotels available in Shepherdsville.
What companies run services between St. Louis, MO, USA and Shepherdsville, KY, USA?
You can take a bus from St Louis Bus Station to Shepherdsville via Evansville, IN and Louisville, KY in around 7h 14m. Alternatively, Southwest Airlines, American Airlines, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Louisville International Airport (SDF) hourly.
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Louisville International Airport via Atlanta
- Ave. Duration
- 5h 15m
- When
- Every day
- Estimated price
- $160–900
Flights from Lambert–St. Louis International Airport to Louisville International Airport via Detroit
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $150–850
Flights from Lambert–St. Louis International Airport to Blue Grass Airport via Atlanta
- Ave. Duration
- 4h
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $230–1,300
Flights from Lambert–St. Louis International Airport to Blue Grass Airport via Detroit
- Ave. Duration
- 6h
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $220–1,300
Flights from Lambert–St. Louis International Airport to Blue Grass Airport via Minneapolis
- Ave. Duration
- 5h 5m
- When
- Saturday
- Estimated price
- $290–1,500
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 4h 34m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $130–800
Flights from Lambert–St. Louis International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 4h 45m
- When
- Monday to Thursday
- Estimated price
- $200–1,200
Flights from Lambert–St. Louis International Airport to Blue Grass Airport via Charlotte
- Ave. Duration
- 5h 31m
- When
- Every day
- Estimated price
- $250–1,400
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Louisville International Airport via Chicago Midway
- Ave. Duration
- 3h 45m
- When
- Every day
- Estimated price
- $120–750
Flights from Lambert–St. Louis International Airport to Louisville International Airport via Nashville
- Ave. Duration
- 4h 16m
- When
- Every day
- Estimated price
- $110–750
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Louisville International Airport via Chicago O'Hare
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- $130–800
Flights from Lambert–St. Louis International Airport to Blue Grass Airport via Chicago O'Hare
- Ave. Duration
- 3h 59m
- When
- Every day
- Estimated price
- $200–1,200
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from St Louis Bus Station to Evansville Bus Station
- Ave. Duration
- 3h 35m
- Frequency
- Once daily
- Estimated price
- $27–50
- Website
- https://www.greyhound.com/
- Phone
- +1 502-368-5644 x 135
- Website
- ridewithmiller.com
Bus from Evansville, IN to Louisville, KY
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Estimated price
- $35–55
- Website
- https://ridewithmiller.com
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