There are 3 ways to get from St. Louis to Panama City Beach by plane, taxi or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Panama City  •  3 h 45 min

  1. Fly from St. Louis (STL) to Panama City (ECP) STL - ECP

$302 - $1,368

2 alternative options

Fly to Valparaiso, taxi  •  6 h 19 min

  1. Fly from St. Louis (STL) to Valparaiso (VPS) STL - VPS
  2. Take a taxi from Valparaiso to Panama City Beach

$362 - $1,272

Drive  •  13 h 36 min

  1. Drive from St. Louis to Panama City Beach 786.4 miles

$75 - $120

Questions & Answers

The distance between St. Louis and Panama City Beach is 639 miles. The road distance is 786.4 miles.

Get driving directions

It takes approximately 3 h 45 min to get from St. Louis to Panama City Beach, including transfers.

More details

The quickest flight from St. Louis Airport to Panama City Airport is the direct flight which takes 1 h 45 min.

Search flights

Yes, the driving distance between St. Louis to Panama City Beach is 786 miles. It takes approximately 13 h 36 min to drive from St. Louis to Panama City Beach.

Get driving directions

Southwest Airlines and Delta offer flights from St. Louis Airport to Panama City Airport.

Search flights

There are 1371+ hotels available in Panama City Beach. Prices start at $71 USD per night.

More details

The best way to get from St. Louis to St. Louis Airport is to train which takes 31 min and costs .

More details

Map of how to get from St. Louis to Panama City Beach.
Launch map view
  • Distance: 638.8 miles
  • Duration: 3 h 45 min

What companies run services between St. Louis, MO, USA and Panama City Beach, FL, USA?

Southwest Airlines and Delta fly from St. Louis to Panama City Beach 5 times a day.

Airlines
Delta
Website
delta.com
Flights from St. Louis to Panama City via Atlanta
Ave. Duration
3 h 56 min
When
Every day
Estimated price
$250 - $1,300
Flights from St. Louis to Valparaiso via Atlanta
Ave. Duration
3 h 58 min
When
Every day
Estimated price
$220 - $1,100
Flights from St. Louis to Valparaiso via Covington, Atlanta
Ave. Duration
6 h 29 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$240 - $1,200
American Airlines
Website
aa.com
Flights from St. Louis to Valparaiso via Charlotte
Ave. Duration
4 h 44 min
When
Every day
Estimated price
$270 - $1,200
Flights from St. Louis to Valparaiso via Dallas/Ft.Worth
Ave. Duration
6 h 5 min
When
Every day
Estimated price
$280 - $1,200
Flights from St. Louis to Valparaiso via Chicago O'Hare
Ave. Duration
5 h 9 min
When
Saturday
Estimated price
$270 - $1,200
United Airlines
Website
united.com
Flights from St. Louis to Valparaiso via Houston
Ave. Duration
4 h 59 min
When
Every day
Estimated price
$290 - $1,300
Southwest Airlines
Website
southwest.com
Flights from St. Louis to Panama City
Ave. Duration
1 h 45 min
When
Saturday
Estimated price
$280 - $1,200
Flights from St. Louis to Panama City via Nashville
Ave. Duration
4 h 15 min
When
Saturday
Estimated price
$280 - $1,200
Other operators
Taxi from Valparaiso to Panama City Beach
Ave. Duration
1 h 22 min
Estimated price
$140 - $170
Quickie Taxi
Phone
+1 850-716-6545
Website
quickietaxi.com

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.