There are 6 ways to get from St. Louis to Palermo by plane, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly Lambert–St. Louis International Airport to Palermo Airport
best- Fly from Lambert–St. Louis International Airport (STL) to Palermo Airport (PMO)plane STL - PMO
15h 54m€335–1,207Fly Lambert–St. Louis International Airport to Catania–Fontanarossa Airport, bus
cheapest- Fly from Lambert–St. Louis International Airport (STL) to Catania–Fontanarossa Airport (CTA)plane STL - CTA
- Take the bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazellobus
18h 36m€323–1,229Train to Chicago O'Hare International Airport, fly to Palermo Airport
- Take the train from St. Louis to Chicago Union Stationtrain
- Fly from Chicago O'Hare International Airport (ORD) to Palermo Airport (PMO)plane ORD - PMO
20h 8m€376–925Train to Abraham Lincoln Capital Airport, fly to Palermo Airport
- Take the train from St. Louis to Springfieldtrain
- Fly from Abraham Lincoln Capital Airport (SPI) to Palermo Airport (PMO)plane SPI - PMO
19h 21m€351–942Fly Lambert–St. Louis International Airport to Trapani Airport, bus
- Fly from Lambert–St. Louis International Airport (STL) to Trapani Airport (TPS)plane STL - TPS
- Take the bus from Trapani Birgi Airport to Palermo Via Belgio/Via dei Nebrodibus
23h 6m€438–1,612Train to Chicago O'Hare International Airport, fly to Catania–Fontanarossa Airport, bus
- Take the train from St. Louis to Chicago Union Stationtrain
- Fly from Chicago O'Hare International Airport (ORD) to Catania–Fontanarossa Airport (CTA)plane ORD - CTA
- Take the bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazellobus
22h 50m€644–1,147
Lambert–St. Louis International Airport (STL) to Palermo Airport (PMO) flights
Comparing Your Travel Options
The cheapest way to get from St. Louis to Palermo is to train and fly which costs €370 - €950 and takes 20h 8m.
The fastest way to get from St. Louis to Palermo is to fly which takes 15h 54m and costs €330 - €1300.
The distance between St. Louis and Palermo is 8490 km.
It takes approximately 15h 54m to get from St. Louis to Palermo, including transfers.
Palermo is 6h ahead of St. Louis. It is currently 8:29 AM in St. Louis and 2:29 PM in Palermo.
There are 6138+ hotels available in Palermo.
What companies run services between St. Louis, MO, USA and Palermo, Italy?
Lufthansa flies from Lambert–St. Louis International Airport (STL) to Palermo Airport (PMO) twice a week.
- Website
- lufthansa.com
Flights from Lambert–St. Louis International Airport to Palermo Airport via Frankfurt
- Ave. Duration
- 12h 30m
- When
- Wednesday and Friday
- Estimated price
- €330–1,200
Flights from Chicago O'Hare International Airport to Palermo Airport via Frankfurt
- Ave. Duration
- 11h 50m
- When
- Wednesday to Saturday
- Estimated price
- €230–850
Flights from Chicago O'Hare International Airport to Palermo Airport via Rome
- Ave. Duration
- 12h
- When
- Every day
- Estimated price
- €200–750
Flights from Lambert–St. Louis International Airport to Catania–Fontanarossa Airport via Frankfurt
- Ave. Duration
- 14h 5m
- When
- Friday and Sunday
- Estimated price
- €310–1,200
Flights from Abraham Lincoln Capital Airport to Palermo Airport via Chicago O'Hare International Airport, Rome
- Ave. Duration
- 14h 41m
- When
- Every day
- Estimated price
- €250–900
Flights from Chicago O'Hare International Airport to Catania–Fontanarossa Airport via Frankfurt
- Ave. Duration
- 11h 55m
- When
- Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €220–800
- Website
- ita-airways.com
Flights from Chicago O'Hare International Airport to Palermo Airport via Rome
- Ave. Duration
- 11h 40m
- When
- Every day
- Estimated price
- €200–750
Flights from Abraham Lincoln Capital Airport to Palermo Airport via Chicago O'Hare International Airport, Rome
- Ave. Duration
- 17h 30m
- When
- Every day
- Estimated price
- €250–900
Flights from Chicago O'Hare International Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 11h 35m
- When
- Friday and Sunday
- Estimated price
- €220–650
- Website
- ryanair.com
Flights from Lambert–St. Louis International Airport to Trapani Airport via Frankfurt, Venice
- Ave. Duration
- 18h 10m
- When
- Sunday
- Estimated price
- €480–1,700
Flights from Lambert–St. Louis International Airport to Trapani Airport via Frankfurt, Bologna
- Ave. Duration
- 21h 15m
- When
- Wednesday and Friday
- Estimated price
- €480–1,700
Flights from Lambert–St. Louis International Airport to Trapani Airport via Boston, Venice
- Ave. Duration
- 19h 30m
- When
- Sunday
- Estimated price
- €430–1,600
Flights from Chicago O'Hare International Airport to Catania–Fontanarossa Airport via Rome
- Ave. Duration
- 12h 30m
- When
- Monday
- Estimated price
- €190–700
- Website
- easyjet.com
Flights from Chicago O'Hare International Airport to Palermo Airport via Milan Malpensa
- Ave. Duration
- 11h 20m
- When
- Thursday
- Estimated price
- €200–750
Flights from Abraham Lincoln Capital Airport to Palermo Airport via Chicago O'Hare International Airport, Naples
- Ave. Duration
- 15h 36m
- When
- Monday
- Estimated price
- €250–950
Flights from Chicago O'Hare International Airport to Catania–Fontanarossa Airport via Naples
- Ave. Duration
- 11h 25m
- When
- Friday
- Estimated price
- €190–700
Flights from Chicago O'Hare International Airport to Catania–Fontanarossa Airport via Milan Malpensa
- Ave. Duration
- 11h 30m
- When
- Wednesday
- Estimated price
- €190–700
- Website
- swiss.com
Flights from Chicago O'Hare International Airport to Palermo Airport via Zurich
- Ave. Duration
- 15h 45m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- €220–700
Flights from Chicago O'Hare International Airport to Palermo Airport via Rome
- Ave. Duration
- 12h
- When
- Every day
- Estimated price
- €200–750
Flights from Abraham Lincoln Capital Airport to Palermo Airport via Chicago O'Hare International Airport, Rome
- Ave. Duration
- 14h 41m
- When
- Every day
- Estimated price
- €250–900
- Website
- airfrance.com
Flights from Chicago O'Hare International Airport to Palermo Airport via Paris Charles de Gaulle
- Ave. Duration
- 16h 25m
- When
- Friday
- Estimated price
- €200–750
Flights from Chicago O'Hare International Airport to Palermo Airport via Rome
- Ave. Duration
- 12h
- When
- Every day
- Estimated price
- €200–750
Flights from Abraham Lincoln Capital Airport to Palermo Airport via Chicago O'Hare International Airport, Rome
- Ave. Duration
- 14h 41m
- When
- Every day
- Estimated price
- €250–900
- Website
- vueling.com
Flights from Abraham Lincoln Capital Airport to Palermo Airport via Chicago O'Hare International Airport, Barcelona
- Ave. Duration
- 20h 31m
- When
- Tuesday, Thursday, and Saturday
- Estimated price
- €250–900
- Website
- brusselsairlines.com
Flights from Chicago O'Hare International Airport to Catania–Fontanarossa Airport via Brussels
- Ave. Duration
- 13h 50m
- When
- Monday and Friday
- Estimated price
- €200–700
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- €130–220
- Website
- Amtrak
Train from St. Louis to Springfield
- Ave. Duration
- 1h 38m
- Frequency
- 5 times a day
- Estimated price
- €45–75
- Website
- Amtrak
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- €130–220
- Website
- Amtrak
- Phone
- 800 21 10 20
- saisautolineeweb@gmail.com
- Website
- SAIS Autolinee
Bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazello
- Ave. Duration
- 2h 30m
- Frequency
- Every 3 hours
- Estimated price
- €11–16
- Schedules at
- SAIS Autolinee
Bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazello
- Ave. Duration
- 2h 30m
- Frequency
- Every 3 hours
- Estimated price
- €11–16
- Schedules at
- SAIS Autolinee
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- Flixbus
Bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazello
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- €18–27
- Website
- Flixbus
Bus from Catania Fontanarossa Airport Bus Stop to Palermo Via Tommaso Fazello
- Ave. Duration
- 3h 35m
- Frequency
- Twice daily
- Estimated price
- €18–27
- Website
- Flixbus
- Phone
- (+39) 0923 98.11.20
- Website
- Autoservizi Salemi Srl
Bus from Trapani Birgi Airport to Palermo Via Belgio/Via dei Nebrodi
- Ave. Duration
- 1h 25m
- Frequency
- 6 times a week
- Estimated price
- €6–10
- Schedules at
- Autoservizi Salemi Srl
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