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How to get fromSt. Louis to Ohioby plane, bus (Greyhound, Flixbus), car or bus (Greyhound)

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There are 7 ways to get from St. Louis to Ohio by plane, bus (Greyhound, Flixbus), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Cleveland-Hopkins International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Cleveland-Hopkins International Airport (CLE)planeSTL - CLE
    3h 37m
    $186–456

  2. Bus (Greyhound)

    cheapest
    1. Take the bus from St Louis Bus Station to ColumbusbusGreyhound US0421
    9h 40m
    $65–95

  3. Bus via Indianapolis

    1. Take the bus from St Louis Bus Station to Indianapolis Union StationbusGreyhound US0421
    2. Take the bus from Indianapolis to ColumbusbusFlixBus N2640 / ...
    9h 4m
    $66–124

  4. Drive 416.2 mi

    1. Drive from St. Louis to Columbuscar416.2 mi
    6h 52m
    $76–110

  5. Fly to John Glenn Columbus International Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to John Glenn Columbus International Airport (CMH)planeSTL - CMH
    4h
    $284–606

  6. Fly to Covington

    1. Fly from Lambert–St. Louis International Airport (STL) to Covington (CVG)planeSTL - CVG
    6h 36m
    $166–958

  7. Fly to Dayton

    1. Fly from Lambert–St. Louis International Airport (STL) to Dayton (DAY)planeSTL - DAY
    6h 47m
    $90–554

St. Louis to Ohio by bus and foot

Calendar13Weekly Services
Duration9h 4mAverage Duration
Ticket$66Cheapest Price
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Questions & Answers

What companies run services between St. Louis, MO, USA and Ohio, USA?

Southwest Airlines, Delta, and American Airlines fly from Lambert–St. Louis International Airport (STL) to Cleveland-Hopkins International Airport (CLE) every 4 hours. Alternatively, you can take a bus from St Louis Bus Station to Columbus via Indianapolis, Illinois St (Greyhound Bus Station) and Indianapolis in around 9h 4m.

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