Rome2Rio

How to get fromSt. Louis to Natchezby bus, train, car, plane or taxi

Find Transport to Natchez

See all options

There are 7 ways to get from St. Louis to Natchez by bus, train, car, plane, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, train, drive

    best
    1. Take the bus from St Louis Bus Station to Jacksonbus bus
    2. Take the train from Jackson to Brookhaven Stationtrain train
    3. Drive from Brookhaven Station to Natchezcar car
    15h 8m
    $76–197

  2. Bus, train, drive via Carbondale

    1. Take the bus from St. Louis to Carbondalebus bus
    2. Take the train from Carbondale to Brookhaven Stationtrain train
    3. Drive from Brookhaven Station to Natchezcar car
    15h 17m
    $84–218

  3. Drive 571.7 mi

    1. Drive from St. Louis to Natchezcar car 571.7 mi
    10h 32m
    $105–151

  4. Fly to Natchez

    1. Fly from Lambert–St. Louis International Airport (STL) to Natchez (HEZ)plane plane STL - HEZ
    9h 12m
    $150–688

  5. Fly to Baton Rouge Metropolitan Airport, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Baton Rouge Metropolitan Airport (BTR)plane plane STL - BTR
    2. Drive from Baton-Rouge-Airport-BTR to Natchezcar car
    7h 32m
    $138–676

  6. Fly to Alexandria International Airport, taxi

    1. Fly from Lambert–St. Louis International Airport (STL) to Alexandria International Airport (AEX)plane plane STL - AEX
    2. Take the taxi from Alexandria International Airport (AEX) to Natcheztaxi taxi
    7h 51m
    $134–678

  7. Fly to Jackson/Vicksburg, train, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Jackson/Vicksburg (JAN)plane plane STL - JAN
    2. Take the train from Jackson to Brookhaven Stationtrain train
    3. Drive from Brookhaven Station to Natchezcar car
    8h 38m
    $150–680

Lambert–St. Louis International Airport (STL) to Natchez (HEZ) flights

Calendar10Weekly Planes
Duration7h 25mAverage Duration
Ticket$127Cheapest Price
See schedules

Questions & Answers

What companies run services between St. Louis, MO, USA and Natchez, MS, USA?

United Airlines and American Airlines fly from Lambert–St. Louis International Airport (STL) to Natchez (HEZ) once daily.

Airlines
Train operators
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from St. Louis

Trips to Natchez

Popular routes