There are 8 ways to get from St. Louis to Natchez by plane, bus, train, car, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Natchez
best- Fly from Lambert–St. Louis International Airport (STL) to Natchez (HEZ)plane STL - HEZ
6h 22m$140–638Drive 571.7 mi
cheapest- Drive from St. Louis to Natchezcar 571.7 mi
10h 24m$105–151Bus, train, drive
- Take the bus from St Louis Bus Station to Jacksonbus
- Take the train from Jackson to Brookhaven Stationtrain
- Drive from Brookhaven Station to Natchezcar
14h 54m$109–211Bus, train, drive via Carbondale
- Take the bus from St Louis Bus Station to Carbondale Intermodal Stationbus
- Take the train from Carbondale to Brookhaven Stationtrain
- Drive from Brookhaven Station to Natchezcar
14h 54m$165–377Fly to Baton Rouge Metropolitan Airport, drive
- Fly from Lambert–St. Louis International Airport (STL) to Baton Rouge Metropolitan Airport (BTR)plane STL - BTR
- Drive from Baton-Rouge-Airport-BTR to Natchezcar
7h 40m$128–626Fly to Alexandria International Airport, taxi
- Fly from Lambert–St. Louis International Airport (STL) to Alexandria International Airport (AEX)plane STL - AEX
- Take the taxi from Alexandria International Airport (AEX) to Natcheztaxi
7h 33m$124–578Fly to Monroe Regional Airport, taxi
- Fly from Lambert–St. Louis International Airport (STL) to Monroe Regional Airport (MLU)plane STL - MLU
- Take the taxi from Monroe Regional Airport (MLU) to Natcheztaxi
7h 56m$124–578Fly to Jackson/Vicksburg, train, drive
- Fly from Lambert–St. Louis International Airport (STL) to Jackson/Vicksburg (JAN)plane STL - JAN
- Take the train from Jackson to Brookhaven Stationtrain
- Drive from Brookhaven Station to Natchezcar
8h 32m$148–574
Lambert–St. Louis International Airport (STL) to Natchez (HEZ) flights
Questions & Answers
The cheapest way to get from St. Louis to Natchez is to drive which costs $100 - $160 and takes 10h 24m.
The fastest way to get from St. Louis to Natchez is to fly which takes 6h 22m and costs $140 - $650.
The distance between St. Louis and Natchez is 522 miles. The road distance is 575 miles.
It takes approximately 6h 22m to get from St. Louis to Natchez, including transfers.
Yes, the driving distance between St. Louis to Natchez is 575 miles. It takes approximately 10h 24m to drive from St. Louis to Natchez.
There are 57+ hotels available in Natchez.
What companies run services between St. Louis, MO, USA and Natchez, MS, USA?
United Airlines flies from Lambert–St. Louis International Airport (STL) to Natchez (HEZ) twice daily.
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Baton Rouge Metropolitan Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 2m
- When
- Every day
- Estimated price
- $110–600
Flights from Lambert–St. Louis International Airport to Baton Rouge Metropolitan Airport via Charlotte
- Ave. Duration
- 5h 13m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $140–700
Flights from Lambert–St. Louis International Airport to Alexandria International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $100–550
Flights from Lambert–St. Louis International Airport to Monroe Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 4h 37m
- When
- Every day
- Estimated price
- $100–550
Flights from Lambert–St. Louis International Airport to Jackson/Vicksburg via Dallas/Ft.Worth
- Ave. Duration
- 5h 32m
- When
- Every day
- Estimated price
- $110–600
Flights from Lambert–St. Louis International Airport to Jackson/Vicksburg via Charlotte
- Ave. Duration
- 6h 10m
- When
- Every day
- Estimated price
- $130–650
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Baton Rouge Metropolitan Airport via Atlanta
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $110–600
Flights from Lambert–St. Louis International Airport to Alexandria International Airport via Atlanta
- Ave. Duration
- 5h 15m
- When
- Every day
- Estimated price
- $110–600
Flights from Lambert–St. Louis International Airport to Monroe Regional Airport via Atlanta
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $110–600
Flights from Lambert–St. Louis International Airport to Jackson/Vicksburg via Atlanta
- Ave. Duration
- 4h 44m
- When
- Every day
- Estimated price
- $100–550
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Natchez via Houston
- Ave. Duration
- 5h 45m
- When
- Every day
- Estimated price
- $110–600
Flights from Lambert–St. Louis International Airport to Baton Rouge Metropolitan Airport via Houston
- Ave. Duration
- 5h 3m
- When
- Every day
- Estimated price
- $110–600
Flights from Lambert–St. Louis International Airport to Alexandria International Airport via Houston
- Ave. Duration
- 5h 36m
- When
- Every day
- Estimated price
- $100–550
Flights from Lambert–St. Louis International Airport to Jackson/Vicksburg via Houston
- Ave. Duration
- 5h 6m
- When
- Every day
- Estimated price
- $120–600
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Jackson/Vicksburg via Nashville
- Ave. Duration
- 4h 25m
- When
- Tuesday to Friday
- Estimated price
- $80–470
Flights from Lambert–St. Louis International Airport to Jackson/Vicksburg via Houston Hobby Apt
- Ave. Duration
- 5h 33m
- When
- Tuesday to Saturday
- Estimated price
- $120–650
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Jackson to Brookhaven Station
- Ave. Duration
- 56 min
- Frequency
- Once daily
- Estimated price
- $15–35
- Website
- https://www.amtrak.com/home.html
Train from Carbondale to Brookhaven Station
- Ave. Duration
- 10h 51m
- Frequency
- Once daily
- Estimated price
- $140–310
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from St Louis Bus Station to Jackson
- Ave. Duration
- 11h 45m
- Frequency
- Once daily
- Estimated price
- $80–160
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- https://www.flixbus.com
Bus from St Louis Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 1h 50m
- Frequency
- Once daily
- Estimated price
- $13–23
- Schedules at
- flixbus.com
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from St Louis Bus Station to Carbondale Intermodal Station
- Ave. Duration
- 2h
- Frequency
- Once daily
- Estimated price
- $30–55
- Website
- https://www.amtrak.com/home.html
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