There are 5 ways to get from St. Louis to Muscatine by train, bus, car, plane, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus, drive (Amtrak)
best- Take the train from St. Louis to Springfieldtrain
- Take the bus from Springfield to Galesburg Amtrak Stationbus
- Drive from Galesburg Amtrak Station to Muscatinecar
6h 37mDrive 233.6 mi
cheapest- Drive from St. Louis to Muscatinecar 233.6 mi
5h 34m$43–62Fly to Quad City International Airport, taxi
- Fly from Lambert–St. Louis International Airport (STL) to Quad City International Airport (MLI)plane STL - MLI
- Take the taxi from Moline-Airport-MLI to Muscatinetaxi
5h 54m$158–582Bus, drive
- Take the bus from St Louis Bus Station to Springfield SMTD Transfer Centerbus
- Take the bus from Springfield to Galesburg Amtrak Stationbus
- Drive from Galesburg Amtrak Station to Muscatinecar
7h 20mFly to The Eastern Iowa Airport, drive
- Fly from Lambert–St. Louis International Airport (STL) to The Eastern Iowa Airport (CID)plane STL - CID
- Drive from Cedar-Rapids-Airport-CID to Muscatinecar
6h 18m$98–568
Lambert–St. Louis International Airport (STL) to Quad City International Airport (MLI) flights
Questions & Answers
The cheapest way to get from St. Louis to Muscatine is to drive which costs $40 - $65 and takes 5h 34m.
The fastest way to get from St. Louis to Muscatine is to drive which takes 5h 34m and costs $40 - $65.
The distance between St. Louis and Muscatine is 283 miles. The road distance is 235 miles.
It takes approximately 6h 37m to get from St. Louis to Muscatine, including transfers.
Yes, the driving distance between St. Louis to Muscatine is 235 miles. It takes approximately 5h 34m to drive from St. Louis to Muscatine.
There are eight+ hotels available in Muscatine.
What companies run services between St. Louis, MO, USA and Muscatine, IA, USA?
There is no direct connection from St. Louis to Muscatine. However, you can take the train to Springfield, walk to Springfield, take the bus to Galesburg Amtrak Station, then drive to Muscatine. Alternatively, you can drive from St. Louis to Muscatine in around 5h 34m.
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Quad City International Airport via Chicago O'Hare
- Ave. Duration
- 4h 17m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $80–490
Flights from Lambert–St. Louis International Airport to Quad City International Airport via Charlotte
- Ave. Duration
- 5h 39m
- When
- Every day
- Estimated price
- $150–750
Flights from Lambert–St. Louis International Airport to Quad City International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 53m
- When
- Monday, Thursday, and Friday
- Estimated price
- $150–750
Flights from Lambert–St. Louis International Airport to The Eastern Iowa Airport via Chicago O'Hare
- Ave. Duration
- 3h 36m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $85–550
Flights from Lambert–St. Louis International Airport to The Eastern Iowa Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $150–750
Flights from Lambert–St. Louis International Airport to The Eastern Iowa Airport via Charlotte
- Ave. Duration
- 7h 11m
- When
- Every day
- Estimated price
- $160–750
Flights from Lambert–St. Louis International Airport to The Eastern Iowa Airport via Reagan Washington
- Ave. Duration
- 7h 42m
- When
- Sunday
- Estimated price
- $180–800
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Quad City International Airport via Chicago O'Hare
- Ave. Duration
- 4h 5m
- When
- Every day
- Estimated price
- $80–490
Flights from Lambert–St. Louis International Airport to Quad City International Airport via Denver
- Ave. Duration
- 5h 49m
- When
- Every day
- Estimated price
- $180–800
Flights from Lambert–St. Louis International Airport to The Eastern Iowa Airport via Chicago O'Hare
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $85–550
Flights from Lambert–St. Louis International Airport to The Eastern Iowa Airport via Denver
- Ave. Duration
- 5h 47m
- When
- Every day
- Estimated price
- $170–800
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Quad City International Airport via Atlanta
- Ave. Duration
- 5h 37m
- When
- Every day
- Estimated price
- $140–700
Flights from Lambert–St. Louis International Airport to The Eastern Iowa Airport via Minneapolis
- Ave. Duration
- 4h 57m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–600
Flights from Lambert–St. Louis International Airport to The Eastern Iowa Airport via Atlanta
- Ave. Duration
- 6h 6m
- When
- Every day
- Estimated price
- $150–750
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from St. Louis to Springfield
- Ave. Duration
- 1h 38m
- Frequency
- 5 times a day
- Estimated price
- $18–50
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Springfield to Galesburg Amtrak Station
- Ave. Duration
- 2h 15m
- Frequency
- Once daily
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from St Louis Bus Station to Springfield SMTD Transfer Center
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $16–24
- Schedules at
- flixbus.com
- Ave. Duration
- 46 min
- Estimated price
- $75–90
Larry's Cab
- Phone
- +1 563-388-7179
Good to Go Taxi Cab Service
- Phone
- +1 563-424-2039
- Website
- goodtogotaxi.com
Dana's Cabs
- Phone
- +1 563-323-2227
- Website
- danascabs.com
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