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How to get fromSt. Louis to Murrells Inletby plane, bus (Amtrak, Flixbus, Greyhound), car, train, or bus (Greyhound, Flixbus)

Find Transport to Murrells Inlet

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There are 5 ways to get from St. Louis to Murrells Inlet by plane, bus (Amtrak, Flixbus, Greyhound), car, train, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Lambert–St. Louis International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Myrtle Beach (MYR)plane plane STL - MYR
    3h 47m
    $132–542

  2. Train to Midamerica St. Louis Airport, fly

    cheapest
    1. Take the train from CIVIC CENTER station to SHILOH-SCOTT stationtrain train
    2. Fly from Midamerica St. Louis Airport (BLV) to Myrtle Beach (MYR)plane plane BLV - MYR
    4h 8m
    $126–420

  3. Bus via Carbondale

    1. Take the bus from St. Louis to Carbondalebus bus
    2. Take the bus from Carbondale Intermodal Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus
    21h 6m
    $163–311

  4. Drive 889.2 mi

    1. Drive from St. Louis to Murrells Inletcar car 889.2 mi
    15h 44m
    $163–235

  5. Bus

    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus bus Greyhound US0186
    2. Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus bus Greyhound US0641S
    22h 1m
    $168–309

Lambert–St. Louis International Airport (STL) to Myrtle Beach (MYR) flights

Calendar37Weekly Planes
Duration3h 34mAverage Duration
Ticket$94Cheapest Price
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Questions & Answers

Map of how to get from St. Louis to Murrells Inlet.ExpandLaunch map view
  • Distance: 753.6 mi
  • Duration: 3h 47m

What companies run services between St. Louis, MO, USA and Murrells Inlet, SC, USA?

Southwest Airlines, Delta, and American Airlines fly from Lambert–St. Louis International Airport (STL) to Myrtle Beach (MYR) 5 times a day. Alternatively, you can take a bus from St. Louis to Murrells Inlet via Carbondale Intermodal Station, Atlanta Bus Station, and Myrtle Beach Bus Station in around 21h 6m.

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