What is the cheapest way to get from St. Louis to Murphysboro?

The cheapest way to get from St. Louis to Murphysboro is to drive which costs $16 - $24 and takes 2h 9m.

What is the fastest way to get from St. Louis to Murphysboro?

The fastest way to get from St. Louis to Murphysboro is to drive which takes 2h 9m and costs $16 - $24.

How far is it from St. Louis to Murphysboro?

The distance between St. Louis and Murphysboro is 104 miles. The road distance is 88.9 miles.

How do I travel from St. Louis to Murphysboro without a car?

The best way to get from St. Louis to Murphysboro without a car is to bus which takes 2h 10m and costs $40 - $95.

How long does it take to get from St. Louis to Murphysboro?

It takes approximately 2h 10m to get from St. Louis to Murphysboro, including transfers.

Can I drive from St. Louis to Murphysboro?

Yes, the driving distance between St. Louis to Murphysboro is 89 miles. It takes approximately 2h 9m to drive from St. Louis to Murphysboro.

Where can I stay near Murphysboro?

There are 26+ hotels available in Murphysboro.

St. Louis to Murphysboro - 2 ways to travel via bus, and car

There are 2 ways to get from St. Louis to Murphysboro by bus (Amtrak, Flixbus) or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

Bus
best
1. Take the bus from St. Louis to CarbondaleAmtrak Thruway Connecting Service
2h 10m
$41–92
Drive 88.3 mi
cheapest
1. Drive from St. Louis to Murphysboro88.3 mi
2h 9m
$17–24

Questions & Answers

Map of how to get from St. Louis to Murphysboro.

Launch map view

Distance: 103.8 mi
Duration: 2h 10m

What companies run services between St. Louis, MO, USA and Murphysboro, IL, USA?

Amtrak operates a bus from St. Louis to Carbondale once daily, and the journey takes 2h. Flixbus USA also services this route once daily.

Operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.