There are 4 ways to get from St. Louis to Mitchell by plane, bus, bus (Greyhound), car, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, bus
best- Fly from Lambert–St. Louis International Airport (STL) to Sioux Falls (FSD)plane STL - FSD
- Take the bus from Sioux Falls to Mitchellbus
7h 32m$128–536Drive 674.7 mi
cheapest- Drive from St. Louis to Mitchellcar 674.7 mi
10h 58m$124–178Bus
- Take the bus from St Louis Bus Station to Kansas City Bus Stationbus
- Take the bus from Kansas City to Sioux Fallsbus
- Take the bus from Sioux Falls to Mitchellbus
15h 40m$159–251Train, bus
- Take the train from St. Louis to Kansas Citytrain
- Take the bus from Kansas City to Sioux Fallsbus
- Take the bus from Sioux Falls to Mitchellbus
18h 6m$211–363
Lambert–St. Louis International Airport (STL) to Sioux Falls (FSD) flights
Questions & Answers
The cheapest way to get from St. Louis to Mitchell is to drive which costs $120 - $180 and takes 10h 58m.
The fastest way to get from St. Louis to Mitchell is to fly and bus which takes 7h 32m and costs $120 - $550.
No, there is no direct bus from St. Louis station to Mitchell. However, there are services departing from St Louis Bus Station and arriving at Mitchell via Kansas City and Sioux Falls. The journey, including transfers, takes approximately 15h 40m.
The distance between St. Louis and Mitchell is 559 miles. The road distance is 678.6 miles.
The best way to get from St. Louis to Mitchell without a car is to bus which takes 15h 40m and costs $150 - $260.
It takes approximately 7h 32m to get from St. Louis to Mitchell, including transfers.
St. Louis to Mitchell bus services, operated by Greyhound USA, depart from St Louis Bus Station.
St. Louis to Mitchell bus services, operated by Greyhound USA, arrive at Kansas City Bus Station.
Yes, the driving distance between St. Louis to Mitchell is 679 miles. It takes approximately 10h 58m to drive from St. Louis to Mitchell.
There are 14+ hotels available in Mitchell.
What companies run services between St. Louis, MO, USA and Mitchell, SD, USA?
You can take a bus from St Louis Bus Station to Mitchell via Kansas City Bus Station, Kansas City, and Sioux Falls in around 15h 40m.
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Sioux Falls via Chicago O'Hare
- Ave. Duration
- 4h 44m
- When
- Every day
- Estimated price
- $95–500
Flights from Lambert–St. Louis International Airport to Sioux Falls via Denver
- Ave. Duration
- 6h 37m
- When
- Every day
- Estimated price
- $140–650
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Sioux Falls via Minneapolis
- Ave. Duration
- 4h 22m
- When
- Every day
- Estimated price
- $90–480
Flights from Lambert–St. Louis International Airport to Sioux Falls via Atlanta
- Ave. Duration
- 7h 7m
- When
- Every day
- Estimated price
- $160–700
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Sioux Falls via Chicago O'Hare
- Ave. Duration
- 6h 5m
- When
- Every day
- Estimated price
- $95–500
Flights from Lambert–St. Louis International Airport to Sioux Falls via Dallas/Ft.Worth
- Ave. Duration
- 6h 45m
- When
- Every day
- Estimated price
- $140–650
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from St. Louis to Kansas City
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $90–190
- Website
- https://www.amtrak.com/home.html
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Sioux Falls to Mitchell
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $26–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $26–40
Bus from Kansas City to Sioux Falls
- Ave. Duration
- 8h 35m
- Frequency
- Once daily
- Estimated price
- $95–140
- Book at
- https://www.jeffersonlines.com
- Adult
- $95–140
Bus from Sioux Falls to Mitchell
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $26–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $26–40
Bus from Kansas City to Sioux Falls
- Ave. Duration
- 8h 35m
- Frequency
- Once daily
- Estimated price
- $95–140
- Book at
- https://www.jeffersonlines.com
- Adult
- $95–140
Bus from Sioux Falls to Mitchell
- Ave. Duration
- 1h 5m
- Frequency
- Twice daily
- Estimated price
- $26–40
- Book at
- https://www.jeffersonlines.com
- Adult
- $26–40
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from St Louis Bus Station to Kansas City Bus Station
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $35–75
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
Why you should take the train in the US
Read the travel guide









