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How to get fromSt. Louis to Mesaby plane, bus (Greyhound), train, bus or car

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There are 5 ways to get from St. Louis to Mesa by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Phoenix (PHX)plane plane STL - PHX
    5h 58m
    $194–954

  2. Bus (Greyhound)

    1. Take the bus from St Louis Bus Station to Phoenix Bus Stationbus bus Greyhound US1210
    30h 21m
    $288–506

  3. Train, bus via Kansas City

    1. Take the train from St. Louis to Kansas Citytrain train
    2. Take the train from Kansas City to Flagstafftrain train
    3. Take the bus from Flagstaff Train Station to Phoenix Sky Harbor Airport/44th Street Sky Train Stationbus bus
    34h 47m
    $362–824

  4. Drive 1,438.6 mi

    1. Drive from St. Louis to Mesacar car 1,438.6 mi
    23h 6m
    $263–380

  5. Train, bus (Amtrak)

    1. Take the train from St. Louis to Maricopa Amtraktrain train Texas Eagle
    2. Take the bus from Maricopa Amtrak to North Phoenix Metro Center Transit Stationbus bus Amtrak Thruway Connecting Service
    2d 9h
    $476–1,065

St. Louis to Mesa by train, bus, and tram

Calendar8Weekly Services
Duration34h 47mAverage Duration
Ticket$362Cheapest Price
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Questions & Answers

What companies run services between St. Louis, MO, USA and Mesa, AZ, USA?

American Airlines, Frontier Airlines, and Southwest Airlines fly from Lambert–St. Louis International Airport (STL) to Phoenix (PHX) every 3 hours. Alternatively, Greyhound USA operates a bus from St Louis Bus Station to Phoenix Bus Station twice daily. Tickets cost $250–470 and the journey takes 30h.

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Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

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