There are 5 ways to get from St. Louis to Mequon by plane, taxi, train (Amtrak), bus (Flixbus, Greyhound), car, train, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly, taxi
best- Fly from Lambert–St. Louis International Airport (STL) to General Mitchell International Airport (MKE)STL - MKE
- Take the taxi from Teutonia & Good Hope to Mequon
4h 13m$278–482Drive 385.3 mi
cheapest- Drive from St. Louis to Mequon385.3 mi
6h 29m$71–102Train (Amtrak)
- Take the train from St. Louis to Chicago Union StationLincoln Service / ...
- Take the train from Chicago Union Station to MilwaukeeHiawatha Service / ...
7h 53m$104–403Bus
- Take the bus from St Louis Bus Station to Chicago Bus StationFlixBus N2521 / ...
- Take the bus from Chicago Bus Station to Milwaukee Intermodal StationGreyhound US0150 / ...
10h 4m$74–153Train, bus
- Take the train from St. Louis to Summit AmtrakLincoln Service / ...
- Take the bus from Multi-Modal/Rental Car Facility to Milwaukee Intermodal/Amtrak StationWisconsin Coach Lines
10h 4m$83–164
Lambert–St. Louis International Airport (STL) to General Mitchell International Airport (MKE) flights
Questions & Answers
The cheapest way to get from St. Louis to Mequon is to drive which costs $70 - $110 and takes 6h 29m.
The fastest way to get from St. Louis to Mequon is to fly and taxi which takes 4h 13m and costs $270 - $490.
The distance between St. Louis and Mequon is 358 miles. The road distance is 387.6 miles.
The best way to get from St. Louis to Mequon without a car is to train which takes 7h 53m and costs $100 - $410.
It takes approximately 4h 13m to get from St. Louis to Mequon, including transfers.
The best way to get from St. Louis to Mequon is to train which takes 7h 53m and costs $100 - $410. Alternatively, you can bus, which costs $70 - $160 and takes 10h 4m.
Yes, the driving distance between St. Louis to Mequon is 388 miles. It takes approximately 6h 29m to drive from St. Louis to Mequon.
There are 240+ hotels available in Mequon.
What companies run services between St. Louis, MO, USA and Mequon, WI, USA?
You can take a train from St. Louis to Mequon via Chicago Union Station and Milwaukee in around 7h 53m. Alternatively, you can take a bus from St Louis Bus Station to Mequon via Chicago Bus Station, Milwaukee Intermodal Station, N5 & Clybourn, and Service Road & Schroeder in around 10h 4m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to General Mitchell International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $140–950
Flights from Lambert–St. Louis International Airport to General Mitchell International Airport via Chicago Midway
- Ave. Duration
- 3h 12m
- When
- Monday, Thursday, and Friday
- Estimated price
- $140–950
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- $40–320
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $22–40
- Website
- https://www.amtrak.com/home.html
Train from St. Louis to Summit Amtrak
- Ave. Duration
- 4h 19m
- Frequency
- 4 times a day
- Estimated price
- $30–100
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from St Louis Bus Station to Chicago Bus Station
- Ave. Duration
- 6h 15m
- Frequency
- 3 times a day
- Estimated price
- $35–65
- Schedules at
- flixbus.com
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 55m
- Frequency
- 3 times a day
- Estimated price
- $19–35
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $19–65
- Website
- https://www.greyhound.com/
- Phone
- (866) 912 6224
- questions@coachusa.com
- Website
- coachusa.com
Bus from Multi-Modal/Rental Car Facility to Milwaukee Intermodal/Amtrak Station
- Ave. Duration
- 1h 45m
- Frequency
- Every 2 hours
- Estimated price
- $34–38
- Schedules at
- coachusa.com
- Ave. Duration
- 14 min
- Estimated price
- $22–27
Yellow Taxi of Milwaukee
- Phone
- +1 414-281-1800
- Website
- yellowtaximke.com
Olaa Taxi Milwaukee
- Phone
- +1 414-688-6786
- Website
- olaataxi.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide










