There are 7 ways to get from St. Louis to Manitowoc by train, bus, bus (Flixbus, Greyhound, Amtrak), car, plane, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, bus
best- Take the train from St. Louis to Chicago Union Station
- Take the train from Chicago Union Station to Milwaukee
- Take the bus from Milwaukee to Manitowoc Amtrak Bus Stop
9h 57m$85–348Bus
cheapest- Take the bus from St Louis Bus Station to Chicago Bus Station
- Take the bus from Chicago Bus Station to Milwaukee Intermodal Station
- Take the bus from Milwaukee to Manitowoc Amtrak Bus Stop
11h 33m$81–206Drive 447.7 mi
- Drive from St. Louis to Manitowoc447.7 mi
7h 37m$82–118Fly to Appleton International Airport, taxi
- Fly from Lambert–St. Louis International Airport (STL) to Appleton International Airport (ATW)STL - ATW
- Take the taxi from Appleton International Airport (ATW) to Manitowoc
6h 19m$188–602Train, bus via Des Plaines
- Take the train from St. Louis to Summit Amtrak
- Take the bus from Multi-Modal/Rental Car Facility to Mitchell Airport
- Take the bus from Milwaukee to Manitowoc, WI104
12h 3m$92–202Fly to General Mitchell International Airport, bus
- Fly from Lambert–St. Louis International Airport (STL) to General Mitchell International Airport (MKE)STL - MKE
- Take the bus from Milwaukee to Manitowoc Amtrak Bus Stop
5h 53m$156–992Fly to Green Bay, bus
- Fly from Lambert–St. Louis International Airport (STL) to Green Bay (GRB)STL - GRB
- Take the bus from Green Bay Amtrak Station to Manitowoc Amtrak Bus Stop
7h 11m$126–540
Lambert–St. Louis International Airport (STL) to Appleton International Airport (ATW) flights
Questions & Answers
The cheapest way to get from St. Louis to Manitowoc is to drive which costs $80 - $120 and takes 7h 37m.
The fastest way to get from St. Louis to Manitowoc is to fly and bus which takes 5h 53m and costs $150 - $1,000.
The distance between St. Louis and Manitowoc is 450 miles. The road distance is 450.4 miles.
The best way to get from St. Louis to Manitowoc without a car is to train and bus which takes 9h 57m and costs $80 - $350.
It takes approximately 9h 57m to get from St. Louis to Manitowoc, including transfers.
Yes, the driving distance between St. Louis to Manitowoc is 450 miles. It takes approximately 7h 37m to drive from St. Louis to Manitowoc.
There are 22+ hotels available in Manitowoc.
What companies run services between St. Louis, MO, USA and Manitowoc, WI, USA?
You can take a bus from St Louis Bus Station to Manitowoc via Chicago Bus Station, Milwaukee Intermodal Station, Milwaukee, and Manitowoc Amtrak Bus Stop in around 11h 33m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 3h 48m
- When
- Every day
- Estimated price
- $75–460
Flights from Lambert–St. Louis International Airport to Green Bay via Chicago O'Hare
- Ave. Duration
- 3h 58m
- When
- Every day
- Estimated price
- $75–460
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Appleton International Airport via Minneapolis
- Ave. Duration
- 6h 9m
- When
- Every day
- Estimated price
- $100–550
Flights from Lambert–St. Louis International Airport to Appleton International Airport via Detroit
- Ave. Duration
- 6h 21m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–550
Flights from Lambert–St. Louis International Airport to Appleton International Airport via Atlanta
- Ave. Duration
- 8h 6m
- When
- Every day
- Estimated price
- $140–700
Flights from Lambert–St. Louis International Airport to Green Bay via Detroit
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- $100–550
Flights from Lambert–St. Louis International Airport to Green Bay via Minneapolis
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $100–550
Flights from Lambert–St. Louis International Airport to Green Bay via Atlanta
- Ave. Duration
- 5h 25m
- When
- Every day
- Estimated price
- $140–700
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 4h 45m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $75–460
Flights from Lambert–St. Louis International Airport to Appleton International Airport via Charlotte
- Ave. Duration
- 5h 31m
- When
- Tuesday
- Estimated price
- $150–700
Flights from Lambert–St. Louis International Airport to Appleton International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 59m
- When
- Saturday
- Estimated price
- $160–750
Flights from Lambert–St. Louis International Airport to Green Bay via Chicago O'Hare
- Ave. Duration
- 4h 15m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $75–460
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to General Mitchell International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $130–850
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- $40–250
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $22–45
- Website
- https://www.amtrak.com/home.html
Train from St. Louis to Summit Amtrak
- Ave. Duration
- 4h 19m
- Frequency
- 4 times a day
- Estimated price
- $30–100
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Milwaukee to Manitowoc Amtrak Bus Stop
- Ave. Duration
- 1h 30m
- Frequency
- Once daily
- Website
- https://www.amtrak.com/home.html
Bus from Green Bay Amtrak Station to Manitowoc Amtrak Bus Stop
- Ave. Duration
- 45 min
- Frequency
- Once daily
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 989-725-5105
- Website
- indiantrails.com
Bus from Milwaukee to Manitowoc Amtrak Bus Stop
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $14–35
- Website
- https://indiantrails.com
Bus from Green Bay Amtrak Station to Manitowoc Amtrak Bus Stop
- Ave. Duration
- 45 min
- Frequency
- Once daily
- Estimated price
- $7–23
- Website
- https://indiantrails.com
- Phone
- +1 800-236-1240
- Website
- golamers.com
Bus from Milwaukee to Manitowoc Amtrak Bus Stop
- Ave. Duration
- 1h 55m
- Frequency
- Twice a week
- Estimated price
- $21–50
- Website
- https://www.golamers.com/
- Schedules at
- https://www.golamers.com/
Bus from Milwaukee to Manitowoc, WI
- Ave. Duration
- 2h 25m
- Frequency
- Twice a week
- Estimated price
- $22–55
- Website
- https://www.golamers.com/
- Schedules at
- https://www.golamers.com/
Bus from Green Bay Amtrak Station to Manitowoc Amtrak Bus Stop
- Ave. Duration
- 55 min
- Frequency
- Twice a week
- Estimated price
- $14–23
- Website
- https://www.golamers.com/
- Schedules at
- https://www.golamers.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from St Louis Bus Station to Chicago Bus Station
- Ave. Duration
- 6h 15m
- Frequency
- 3 times a day
- Estimated price
- $40–90
- Schedules at
- flixbus.com
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 55m
- Frequency
- 3 times a day
- Estimated price
- $20–40
- Schedules at
- flixbus.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Milwaukee Intermodal Station
- Ave. Duration
- 1h 45m
- Frequency
- Twice daily
- Estimated price
- $20–60
- Website
- https://www.greyhound.com/
- Phone
- (866) 912 6224
- questions@coachusa.com
- Website
- coachusa.com
Bus from Multi-Modal/Rental Car Facility to Mitchell Airport
- Ave. Duration
- 1h 20m
- Frequency
- Every 2 hours
- Estimated price
- $31–34
- Schedules at
- coachusa.com
- Ave. Duration
- 1h 11m
- Estimated price
- $110–140
Fox Valley Cab
- Phone
- +1 920-734-4545
- Website
- facebook.com
Appleton Yellow Taxi
- Phone
- +1 920-733-4444
- Website
- appletonyellowtaxi.com
Able Taxi and Tours
- Phone
- +1 920-265-7760
- Website
- abletaxiandtours.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide












