There are 6 ways to get from St. Louis to Lisle by train (Amtrak), bus (Flixbus), car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from St. Louis to Chicago Union Stationtrain Lincoln Service / ...
6h 13m$41–110Bus
- Take the bus from St Louis Bus Station to Champaign Intermodal Trans Ctrbus FlixBus N2521 / ...
- Take the bus from Illinois Terminal to Oakbrook Mallbus Champaign to Chicago ends at Woodfield NB / ...
8h 48m$77–104Drive 272.8 mi
- Drive from St. Louis to Lislecar 272.8 mi
4h 42m$50–72Fly Lambert–St. Louis International Airport to Chicago Midway International Airport, train
- Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)plane STL - MDW
- Take the train from Chicago Union Station to Lisletrain
4h 48m$84–564Fly Lambert–St. Louis International Airport to Chicago O'Hare International Airport, train
- Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)plane STL - ORD
- Take the train from Chicago Union Station to Lisletrain
5h 13m$248–564Train to Abraham Lincoln Capital Airport, fly to Chicago O'Hare International Airport, train
- Take the train from St. Louis to Springfieldtrain
- Fly from Abraham Lincoln Capital Airport (SPI) to Chicago O'Hare International Airport (ORD)plane SPI - ORD
- Take the train from Chicago Union Station to Lisletrain
6h 17m$63–287
St. Louis to Lisle by train (Amtrak)
Questions & Answers
The cheapest way to get from St. Louis to Lisle is to drive which costs $50 - $75 and takes 4h 42m.
The fastest way to get from St. Louis to Lisle is to drive which takes 4h 42m and costs $50 - $75.
No, there is no direct bus from St. Louis station to Lisle. However, there are services departing from St Louis Bus Station and arriving at Ogden Ave & Main St via Illinois Terminal, Oak Brook Center / Macy's and Yorktown Center. The journey, including transfers, takes approximately 8h 48m.
No, there is no direct train from St. Louis to Lisle. However, there are services departing from St. Louis and arriving at Lisle via Chicago Union Station. The journey, including transfers, takes approximately 6h 13m.
The distance between St. Louis and Lisle is 307 miles. The road distance is 274.4 miles.
The best way to get from St. Louis to Lisle without a car is to train which takes 6h 13m and costs $40 - $110.
It takes approximately 6h 13m to get from St. Louis to Lisle, including transfers.
St. Louis to Lisle bus services, operated by Flixbus USA, depart from St Louis Bus Station.
St. Louis to Lisle train services, operated by Amtrak, depart from St. Louis station.
The best way to get from St. Louis to Lisle is to train which takes 6h 13m and costs $40 - $110. Alternatively, you can bus, which costs $75 - $110 and takes 8h 48m.
What companies run services between St. Louis, MO, USA and Lisle, IL, USA?
Amtrak operates a train from St. Louis to Chicago Union Station 5 times a day. Tickets cost $35–110 and the journey takes 4h 55m. Alternatively, you can take a bus from St Louis Bus Station to Ogden Ave & Main St via Champaign Intermodal Trans Ctr, Illinois Terminal, Oak Brook Center / Macy's, and Yorktown Center in around 8h 48m.
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 27m
- When
- Every day
- Estimated price
- $50–340
Flights from Abraham Lincoln Capital Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 12m
- When
- Every day
- Estimated price
- $29–220
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 35m
- When
- Every day
- Estimated price
- $50–340
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 9m
- When
- Every day
- Estimated price
- $75–550
- Website
- gojetairlines.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 34m
- When
- Every day
- Estimated price
- $50–340
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- $35–110
- Website
- https://www.amtrak.com/home.html
Train from St. Louis to Springfield
- Ave. Duration
- 1h 38m
- Frequency
- 5 times a day
- Estimated price
- $15–45
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 312-322-6777
- Website
- metra.com
Train from Chicago Union Station to Lisle
- Ave. Duration
- 56 min
- Frequency
- Hourly
- Estimated price
- $4–6
- Website
- https://metra.com
- Adult
- $4–6
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from St Louis Bus Station to Champaign Intermodal Trans Ctr
- Ave. Duration
- 3h 25m
- Frequency
- 3 times a day
- Estimated price
- $29–40
- Schedules at
- flixbus.com
- Phone
- +1 800-448-0572
- ticketsales@peoriacharter.com
- Website
- peoriacharter.com
Bus from Illinois Terminal to Oakbrook Mall
- Ave. Duration
- 3h 15m
- Frequency
- Twice daily
- Estimated price
- $45–60
- Schedules at
- peoriacharter.com
- cash
- $60
- online
- $45
Want to know more about travelling around United States
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More Questions & Answers
St. Louis to Lisle bus services, operated by Flixbus USA, arrive at Champaign Intermodal Trans Ctr station.
St. Louis to Lisle train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between St. Louis to Lisle is 274 miles. It takes approximately 4h 42m to drive from St. Louis to Lisle.
There are 238+ hotels available in Lisle.