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How to get fromSt. Louis to Key Westby plane, bus (Flixbus, Greyhound), car, bus or ferry

Find Transport to Key West

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There are 5 ways to get from St. Louis to Key West by plane, bus (Flixbus, Greyhound), car, bus, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Lambert–St. Louis International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Key West International Airport (EYW)planeSTL - EYW
    5h 54m
    $184–866

  2. Bus

    cheapest
    1. Take the bus from St Louis Bus Station to Atlanta Bus Stationbus
    2. Take the bus from Atlanta Bus Station to Miami Airport Stationbus
    3. Take the bus from Miami Airport Station to Big Pine Keybus
    4. Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetbusLks
    32h 26m
    $147–385

  3. Drive 1,350.3 mi

    1. Drive from St. Louis to Key Westcar1,350.3 mi
    23h 26m
    $247–356

  4. Bus to Evansville, fly

    1. Take the bus from St Louis Bus Station to Evansville Bus Stationbus
    2. Fly from Evansville (EVV) to Key West International Airport (EYW)planeEVV - EYW
    9h 33m
    $215–887

  5. Bus, ferry

    1. Take the bus from St Louis Bus Station to New Orleans Bus Stationbus
    2. Take the bus from New Orleans Bus Station to Biloxi Transit Centerbus
    3. Take the bus from Biloxi to Fort Myersbus
    4. Take the ferry from Fort Myers Beach, FL to Key West, FLferry
    39h 39m
    $389–556

St. Louis to Key West by bus and foot

Calendar7Weekly Services
Duration32h 26mAverage Duration
Ticket$147Cheapest Price
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Questions & Answers

What companies run services between St. Louis, MO, USA and Key West, FL, USA?

Delta and American Airlines fly from Lambert–St. Louis International Airport (STL) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from St Louis Bus Station to N Roosevelt & 3rd Street via Atlanta Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 32h 26m.

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