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How to get fromSt. Louis to Irvineby plane, bus, train, train (Amtrak), or car

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There are 7 ways to get from St. Louis to Irvine by plane, bus, train, train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to John Wayne Airport Orange County

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to John Wayne Airport Orange County (SNA)plane plane STL - SNA
    7h 1m
    $212–952

  2. Bus, train

    1. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus Greyhound US1210
    2. Take the train from L.A. Union Station to Tustintrain train OC Line
    42h 31m
    $322–615

  3. Train (Amtrak)

    1. Take the train from St. Louis to Kansas Citytrain train Missouri River Runner / ...
    2. Take the train from Kansas City to Fullerton Amtrak Stationtrain train Southwest Chief
    42h 55m
    $586–1,281

  4. Drive 1,807.2 mi

    1. Drive from St. Louis to Irvinecar car 1,807.2 mi
    28h 48m
    $330–477

  5. Fly to Los Angeles International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Los Angeles International Airport (LAX)plane plane STL - LAX
    2. Take the train from L.A. Union Station to Tustintrain train
    8h 15m
    $398–878

  6. Fly to Burbank Bob Hope Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Burbank Bob Hope Airport (BUR)plane plane STL - BUR
    2. Take the train from L.A. Union Station to Tustintrain train
    8h 59m
    $296–1,324

  7. Train, bus

    1. Take the train from St. Louis to Pomona Amtraktrain train Texas Eagle
    2. Take the bus from Ring-Brea Mall to Campus-University Centerbus bus 59
    2d 13h
    $689–1,482

St. Louis to Irvine by bus and train

Calendar7Weekly Services
Duration42h 31mAverage Duration
Ticket$322Cheapest Price
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Questions & Answers

What companies run services between St. Louis, MO, USA and Irvine, CA, USA?

Southwest Airlines, American Airlines, and United Airlines fly from Lambert–St. Louis International Airport (STL) to John Wayne Airport Orange County (SNA) hourly. Alternatively, you can take a train from St. Louis to Tustin via Kansas City, Fullerton Amtrak Station, and Fullerton in around 42h 55m.

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