Rome2Rio

How to get fromSt. Louis to Irvineby plane, bus, train, train (Amtrak), or car

Find Transport to Irvine

See all options
QR code to download the Rome2Rio app

Download the Rome2Rio travel app

Scan QR code with your phone to download the app

Download on the App StoreGet it on Google Play

There are 9 ways to get from St. Louis to Irvine by plane, bus, train, train (Amtrak), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to John Wayne Airport Orange County

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to John Wayne Airport Orange County (SNA)plane plane STL - SNA
    7h 47m
    $174–554

  2. Fly to Los Angeles International Airport, train

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to Los Angeles International Airport (LAX)plane plane STL - LAX
    2. Take the train from L.A. Union Station to Tustintrain train
    8h 25m
    $138–258

  3. Bus, train

    1. Take the bus from St Louis Bus Station to Los Angeles Union Stationbus bus Greyhound US1210
    2. Take the train from L.A. Union Station to Tustintrain train OC Line
    42h 31m
    $351–516

  4. Train (Amtrak)

    1. Take the train from St. Louis to Kansas Citytrain train Missouri River Runner / ...
    2. Take the train from Kansas City to Fullerton Amtrak Stationtrain train Southwest Chief
    42h 55m
    $1,109–1,745

  5. Drive  1,813.1 mi

    1. Drive from St. Louis to Irvinecar car 1,813.1 mi
    28h 34m
    $300–433

  6. Fly to San Diego International Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to San Diego International Airport (SAN)plane plane STL - SAN
    2. Take the train from San Diego to Irvinetrain train
    9h 42m
    $186–276

  7. Fly to Burbank Bob Hope Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Burbank Bob Hope Airport (BUR)plane plane STL - BUR
    2. Take the train from L.A. Union Station to Tustintrain train
    10h 54m
    $166–774

  8. Fly to Long Beach Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Long Beach Airport (LGB)plane plane STL - LGB
    11h 24m
    $152–668

  9. Train, bus

    1. Take the train from St. Louis to Pomona Amtraktrain train Texas Eagle
    2. Take the bus from Ring-Brea Mall to Campus-University Centerbus bus 59
    2d 13h
    $1,324–2,035

St. Louis to Irvine by bus and train

Calendar7Weekly Services
Duration42h 31mAverage Duration
Ticket$351Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from St. Louis to Irvine.ExpandLaunch map view
  • Distance: 1,582.4 mi
  • Duration: 7h 47m

What companies run services between St. Louis, MO, USA and Irvine, CA, USA?

Southwest Airlines, American Airlines, and three other airlines fly from Lambert–St. Louis International Airport (STL) to John Wayne Airport Orange County (SNA) hourly. Alternatively, you can take a train from St. Louis to Tustin via Kansas City, Fullerton Amtrak Station, and Fullerton in around 42h 55m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There