There are 8 ways to get from St. Louis to Iowa City by bus, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus via Burlington, IA  •  7 h 20 min

  1. Take the bus from St Louis, MO to Burlington, IA 1490
  2. Take the bus from Burlington, IA to Iowa City, IA 1490

$72 - $148

Cheapest option

Bus  •  8 h 35 min

  1. Take the bus from St Louis, MO to Iowa City, IA 1490

$50 - $100

6 alternative options

Train, bus  •  9 h 12 min

  1. Take the train from St. Louis Gateway Station Amtrak to Bloomington-Normal Amtrak
  2. Take the bus from Bloomington/Normal, IL to Davenport, IA
  3. Take the bus from Davenport, IA to Iowa City, IA

$92 - $174

Drive  •  4 h 57 min

  1. Drive from St. Louis to Iowa City 261.5 miles

$25 - $40

Fly to Burlington, bus  •  5 h 13 min

  1. Fly from St. Louis (STL) to Burlington (BRL) STL - BRL
  2. Take the bus from Burlington, IA to Iowa City, IA

$128 - $306

Fly to Cedar Rapids  •  6 h 33 min

  1. Fly from St. Louis (STL) to Cedar Rapids (CID) STL - CID

$204 - $987

Fly to Moline, bus  •  6 h 47 min

  1. Fly from St. Louis (STL) to Moline (MLI) STL - MLI
  2. Take the bus from Moline Airport to Iowa City - Coralville

Fly to Des Moines, bus  •  7 h 5 min

  1. Fly from St. Louis (STL) to Des Moines (DSM) STL - DSM
  2. Take the bus from Des Moines, IA to Iowa City, IA

$195 - $800

What companies run services between St. Louis, MO, USA and Iowa City, IA, USA?

You can take a bus from St. Louis to Iowa City via Burlington, IA in around 7 h 20 min. Alternatively, American Airlines, United Airlines and Delta fly from St. Louis to Iowa City hourly.

Airlines
Delta
Website
delta.com
Flights from St. Louis to Cedar Rapids via Detroit
Ave. Duration
5 h 47 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$200 - $1,000
Flights from St. Louis to Cedar Rapids via Minneapolis
Ave. Duration
5 h 10 min
When
Every day
Estimated price
$190 - $950
Flights from St. Louis to Cedar Rapids via Atlanta
Ave. Duration
5 h 14 min
When
Every day
Estimated price
$230 - $1,100
Flights from St. Louis to Moline via Detroit
Ave. Duration
5 h 18 min
When
Every day
Estimated price
$200 - $1,100
Flights from St. Louis to Moline via Atlanta
Ave. Duration
4 h 59 min
When
Every day
Estimated price
$230 - $1,100
Flights from St. Louis to Moline via Minneapolis
Ave. Duration
4 h 49 min
When
Saturday
Estimated price
$200 - $1,000
American Airlines
Website
aa.com
Flights from St. Louis to Cedar Rapids via Chicago O'Hare
Ave. Duration
3 h 56 min
When
Every day
Estimated price
$180 - $950
Flights from St. Louis to Cedar Rapids via Dallas/Ft.Worth
Ave. Duration
5 h 42 min
When
Every day
Estimated price
$250 - $1,100
Flights from St. Louis to Cedar Rapids via Charlotte
Ave. Duration
5 h 35 min
When
Every day
Estimated price
$250 - $1,100
Flights from St. Louis to Moline via Chicago O'Hare
Ave. Duration
3 h 23 min
When
Every day
Estimated price
$180 - $950
Flights from St. Louis to Moline via Dallas/Ft.Worth
Ave. Duration
5 h 32 min
When
Every day
Estimated price
$260 - $1,100
United Airlines
Website
united.com
Flights from St. Louis to Cedar Rapids via Chicago O'Hare
Ave. Duration
4 h 40 min
When
Every day
Estimated price
$200 - $1,000
Flights from St. Louis to Cedar Rapids via Denver
Ave. Duration
6 h 42 min
When
Every day
Estimated price
$270 - $1,200
Flights from St. Louis to Moline via Chicago O'Hare
Ave. Duration
4 h 15 min
When
Every day
Estimated price
$200 - $1,000
Flights from St. Louis to Moline via Denver
Ave. Duration
6 h 58 min
When
Every day
Estimated price
$290 - $1,300
Southwest Airlines
Website
southwest.com
Flights from St. Louis to Des Moines
Ave. Duration
1 h
When
Every day
Estimated price
$160 - $750
Air Choice One
Website
airchoiceone.com
Flights from St. Louis to Burlington
Ave. Duration
1 h 10 min
When
Every day
Estimated price
$80 - $230
Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from St. Louis Gateway Station Amtrak to Bloomington-Normal Amtrak
Ave. Duration
3 h 3 min
Frequency
Every 4 hours
Estimated price
$35 - $85
Website
amtrak.com
Coach Seat
$35 - $55
Flexi Coach Seat
$65 - $95
Business Coach Seat
$60 - $85
Room
$180 - $260
Bus operators
Burlington Trailways
Website
burlingtontrailways.com
Bus from St Louis, MO to Burlington, IA
Ave. Duration
4 h 55 min
Frequency
Once daily
Estimated price
$40 - $100
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Bus from Burlington, IA to Iowa City, IA
Ave. Duration
1 h 25 min
Frequency
Twice daily
Estimated price
$27 - $50
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Bus from St Louis, MO to Iowa City, IA
Ave. Duration
8 h 35 min
Frequency
Once daily
Estimated price
$50 - $100
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Bus from Bloomington/Normal, IL to Davenport, IA
Ave. Duration
3 h 5 min
Frequency
Twice daily
Estimated price
$30 - $50
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Bus from Davenport, IA to Iowa City, IA
Ave. Duration
1 h 11 min
Frequency
Hourly
Estimated price
$25 - $40
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Bus from Des Moines, IA to Iowa City, IA
Ave. Duration
2 h 5 min
Frequency
Every 3 hours
Estimated price
$30 - $45
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Windstar
Phone
+1 888-494-6378
Email
sara@gowindstar.com
Website
gowindstar.com
Bus from Moline Airport to Iowa City - Coralville
Ave. Duration
1 h 5 min
Frequency
Once daily
Schedules at
gowindstar.com

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Questions & Answers

The distance between St. Louis and Iowa City is 356 km. The road distance is 418 km.

The cheapest way to get from St. Louis to Iowa City is to drive which costs $25 - $40 and takes 4 h 57 min.

The quickest way to get from St. Louis to Iowa City is to drive which takes 4 h 57 min and costs $25 - $40.

Yes, there is a direct bus departing from St Louis, MO and arriving at Iowa City, IA. Services depart once daily, and operate every day. The journey takes approximately 8 h 35 min.

It takes approximately 7 h 20 min to get from St. Louis to Iowa City, including transfers.