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How to get fromSt. Louis to Iowaby plane, bus (Greyhound), train, bus or car

Find Transport to Iowa

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There are 6 ways to get from St. Louis to Iowa by plane, bus (Greyhound), train, bus, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Des Moines

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Des Moines (DSM)plane plane STL - DSM
    2h 52m
    $150–924

  2. Bus

    cheapest
    1. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus Greyhound US1200 / ...
    2. Take the bus from Kansas City to Des Moinesbus bus Jefferson 802 / ...
    8h 35m
    $60–170

  3. Train, bus

    1. Take the train from St. Louis to Kansas Citytrain train Missouri River Runner / ...
    2. Take the bus from Kansas City to Des Moinesbus bus Jefferson 802 / ...
    10h 31m
    $62–313

  4. Drive 331.1 mi

    1. Drive from St. Louis to Des Moinescar car 331.1 mi
    6h 35m
    $61–88

  5. Fly to Omaha

    1. Fly from Lambert–St. Louis International Airport (STL) to Omaha (OMA)plane plane STL - OMA
    3h 6m
    $148–882

  6. Fly to Quad City International Airport

    1. Fly from Lambert–St. Louis International Airport (STL) to Quad City International Airport (MLI)plane plane STL - MLI
    6h 41m
    $84–504

Lambert–St. Louis International Airport (STL) to Des Moines (DSM) flights

Calendar13Weekly Planes
Duration1h 10mAverage Duration
Ticket$135Cheapest Price
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Questions & Answers

What companies run services between St. Louis, MO, USA and Iowa, USA?

Southwest Airlines flies from Lambert–St. Louis International Airport (STL) to Des Moines (DSM) twice daily. Alternatively, you can take a bus from St Louis Bus Station to Des Moines via Kansas City and Des Moines in around 8h 35m.

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