There are 5 ways to get from St. Louis to Iowa by plane, bus (Greyhound), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Omaha
best- Fly from Lambert–St. Louis International Airport (STL) to Omaha (OMA)plane STL - OMA
3h 1m$168–982Drive 331.1 mi
cheapest- Drive from St. Louis to Des Moinescar 331.1 mi
6h 35m$61–88Bus (Greyhound)
- Take the bus from St Louis Bus Station to Des Moinesbus Greyhound US0153S
8h 30m$80–146Fly to Des Moines
- Fly from Lambert–St. Louis International Airport (STL) to Des Moines (DSM)plane STL - DSM
5h 35m$200–1,124Fly to Quad City International Airport
- Fly from Lambert–St. Louis International Airport (STL) to Quad City International Airport (MLI)plane STL - MLI
6h 36m$74–464
Lambert–St. Louis International Airport (STL) to Omaha (OMA) flights
Questions & Answers
The cheapest way to get from St. Louis to Iowa is to drive which costs $60 - $90 and takes 6h 35m.
The fastest way to get from St. Louis to Iowa is to fly which takes 3h 1m and costs $160 - $1,000.
The distance between St. Louis and Iowa is 366 miles. The road distance is 333.1 miles.
The best way to get from St. Louis to Iowa without a car is to bus which takes 8h 30m and costs $80 - $150.
It takes approximately 3h 1m to get from St. Louis to Iowa, including transfers.
The best way to get from St. Louis to Iowa is to fly which takes 3h 1m and costs $160 - $1,000. Alternatively, you can bus, which costs $80 - $150 and takes 8h 30m.
Yes, the driving distance between St. Louis to Iowa is 333 miles. It takes approximately 6h 35m to drive from St. Louis to Iowa.
There are 196+ hotels available in Iowa.
What companies run services between St. Louis, MO, USA and Iowa, USA?
Southwest Airlines flies from Lambert–St. Louis International Airport (STL) to Omaha (OMA) twice daily. Alternatively, Greyhound USA operates a bus from St Louis Bus Station to Des Moines once daily. Tickets cost $70–140 and the journey takes 8h 25m.
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- $180–1,100
Flights from Lambert–St. Louis International Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 5h 11m
- When
- Every day
- Estimated price
- $290–1,500
Flights from Lambert–St. Louis International Airport to Quad City International Airport via Chicago O'Hare
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $70–460
Flights from Lambert–St. Louis International Airport to Quad City International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 44m
- When
- Every day
- Estimated price
- $140–750
Flights from Lambert–St. Louis International Airport to Quad City International Airport via Charlotte
- Ave. Duration
- 6h 15m
- When
- Every day
- Estimated price
- $150–750
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 9m
- When
- Every day
- Estimated price
- $180–1,100
Flights from Lambert–St. Louis International Airport to Quad City International Airport via Chicago O'Hare
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $70–460
Flights from Lambert–St. Louis International Airport to Quad City International Airport via Denver
- Ave. Duration
- 6h 11m
- When
- Every day
- Estimated price
- $170–800
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Des Moines via Minneapolis
- Ave. Duration
- 4h 36m
- When
- Every day
- Estimated price
- $200–1,200
Flights from Lambert–St. Louis International Airport to Des Moines via Atlanta
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $300–1,500
Flights from Lambert–St. Louis International Airport to Quad City International Airport via Atlanta
- Ave. Duration
- 5h 22m
- When
- Every day
- Estimated price
- $130–700
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Omaha
- Ave. Duration
- 1h 16m
- When
- Every day
- Estimated price
- $140–950
Flights from Lambert–St. Louis International Airport to Des Moines via Chicago Midway
- Ave. Duration
- 4h 25m
- When
- Monday, Thursday, and Friday
- Estimated price
- $180–1,100
Flights from Lambert–St. Louis International Airport to Des Moines via Denver
- Ave. Duration
- 5h 5m
- When
- Sunday
- Estimated price
- $330–1,600
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from St Louis Bus Station to Des Moines
- Ave. Duration
- 8h 25m
- Frequency
- Once daily
- Estimated price
- $70–140
- Website
- https://www.greyhound.com/
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