There are 6 ways to get from St. Louis to Iowa by plane, bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Des Moines
best- Fly from Lambert–St. Louis International Airport (STL) to Des Moines (DSM)STL - DSM
2h 52m$140–874Train, bus
cheapest- Take the train from St. Louis to Kansas CityMissouri River Runner / ...
- Take the bus from Kansas City to Des MoinesJefferson 802 / ...
10h 28m$59–339Bus
- Take the bus from St Louis to BurlingtonSt Louis
- Take the bus from Burlington to Des MoinesIndianapolis
8h 40m$91–207Drive 331.1 mi
- Drive from St. Louis to Des Moines331.1 mi
6h 34m$61–88Fly to Omaha
- Fly from Lambert–St. Louis International Airport (STL) to Omaha (OMA)STL - OMA
3h 6m$158–832Fly to Quad City International Airport
- Fly from Lambert–St. Louis International Airport (STL) to Quad City International Airport (MLI)STL - MLI
6h 41m$84–484
St. Louis to Iowa by bus
Questions & Answers
The cheapest way to get from St. Louis to Iowa is to drive which costs $60 - $90 and takes 6h 34m.
The fastest way to get from St. Louis to Iowa is to fly which takes 2h 52m and costs $140 - $900.
No, there is no direct bus from St. Louis to Iowa. However, there are services departing from St Louis and arriving at Des Moines via Burlington. The journey, including transfers, takes approximately 8h 40m.
The distance between St. Louis and Iowa is 281 miles. The road distance is 333.1 miles.
The best way to get from St. Louis to Iowa without a car is to bus which takes 8h 40m and costs $90 - $210.
It takes approximately 2h 52m to get from St. Louis to Iowa, including transfers.
St. Louis to Iowa bus services, operated by Burlington Trailways, depart from St Louis station.
The best way to get from St. Louis to Iowa is to fly which takes 2h 52m and costs $140 - $900. Alternatively, you can bus, which costs $90 - $210 and takes 8h 40m.
St. Louis to Iowa bus services, operated by Burlington Trailways, arrive at Burlington station.
Yes, the driving distance between St. Louis to Iowa is 333 miles. It takes approximately 6h 34m to drive from St. Louis to Iowa.
What companies run services between St. Louis, MO, USA and Iowa, USA?
Southwest Airlines flies from Lambert–St. Louis International Airport (STL) to Des Moines (DSM) twice daily. Alternatively, you can take a bus from St Louis to Des Moines via Burlington in around 8h 40m.
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Des Moines
- Ave. Duration
- 1h 10m
- When
- Every day
- Estimated price
- $120–850
Flights from Lambert–St. Louis International Airport to Omaha
- Ave. Duration
- 1h 20m
- When
- Every day
- Estimated price
- $130–800
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Quad City International Airport via Chicago O'Hare
- Ave. Duration
- 4h 35m
- When
- Every day
- Estimated price
- $80–480
Flights from Lambert–St. Louis International Airport to Quad City International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 20m
- When
- Every day
- Estimated price
- $150–750
Flights from Lambert–St. Louis International Airport to Quad City International Airport via Charlotte
- Ave. Duration
- 7h 34m
- When
- Every day
- Estimated price
- $150–750
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Quad City International Airport via Chicago O'Hare
- Ave. Duration
- 4h 45m
- When
- Every day
- Estimated price
- $80–480
Flights from Lambert–St. Louis International Airport to Quad City International Airport via Denver
- Ave. Duration
- 6h 12m
- When
- Every day
- Estimated price
- $170–800
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Quad City International Airport via Atlanta
- Ave. Duration
- 5h 53m
- When
- Every day
- Estimated price
- $140–700
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from St. Louis to Kansas City
- Ave. Duration
- 5h 40m
- Frequency
- Twice daily
- Estimated price
- $30–240
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (319) 753-2864
- info@burlingtontrailways.com
- Website
- burlingtontrailways.com
Bus from St Louis to Burlington
- Ave. Duration
- 4h 35m
- Frequency
- Once daily
- Estimated price
- $50–127
- Website
- https://burlingtontrailways.com
- Saver Fares
- $50–75
- Flexible Fares
- $70–100
- Saver Fare
- $92
- Flex Fare
- $127
Bus from Burlington to Des Moines
- Ave. Duration
- 3h 5m
- Frequency
- Once daily
- Estimated price
- $40–80
- Website
- https://burlingtontrailways.com
- Saver Fares
- $40–60
- Flexible Fares
- $50–80
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Kansas City to Des Moines
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $18–90
- Book at
- https://www.jeffersonlines.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
There are 231+ hotels available in Iowa.