There are 4 ways to get from St. Louis to Indianapolis by bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  6 h 20 min

  1. Take the bus from St Louis, Mo to Champaign, Il 1364 / ...
  2. Take the bus from Champaign, IL to Indianapolis, IN 1401 / ...

$53 - $104

Cheapest option

Bus via Terre Haute, In  •  6 h 39 min

  1. Take the bus from St Louis, Mo to Terre Haute, In 1684
  2. Take the bus from Terre Haute, IN to Indianapolis, IN 0017 / ...

$38 - $79

2 alternative options

Drive  •  4 h 6 min

  1. Drive from St. Louis to Indianapolis 243.1 miles

$23 - $35

Fly  •  5 h 33 min

  1. Fly from St. Louis (STL) to Indianapolis (IND) STL - IND

$154 - $804

Questions & Answers

The cheapest way to get from St. Louis to Indianapolis is to drive which costs $23 - $35 and takes 4 h 6 min.

More details

The quickest way to get from St. Louis to Indianapolis is to drive which takes 4 h 6 min and costs $23 - $35.

More details

The distance between St. Louis and Indianapolis is 370 km. The road distance is 389 km.

Get driving directions

It takes approximately 6 h 20 min to get from St. Louis to Indianapolis, including transfers.

More details

No, there is no direct bus from St. Louis to Indianapolis. However, there are services departing from St Louis, Mo and arriving at Indianapolis, IN via Champaign, IL. The journey, including transfers, takes approximately 6 h 20 min.

More details

What companies run services between St. Louis, MO, USA and Indianapolis, IN, USA?

You can take a bus from St. Louis to Indianapolis via Champaign, Il and Champaign, IL in around 6 h 20 min. Alternatively, Southwest Airlines, American Airlines and two other airlines fly from St. Louis to Indianapolis hourly.

Airlines
United Airlines
Website
united.com
Flights from St. Louis to Indianapolis via Chicago O'Hare
Ave. Duration
3 h 59 min
When
Every day
Estimated price
$170 - $850
Flights from St. Louis to Indianapolis via Washington Dulles
Ave. Duration
4 h 39 min
When
Every day
Estimated price
$210 - $950
Southwest Airlines
Website
southwest.com
Flights from St. Louis to Indianapolis via Chicago Midway
Ave. Duration
3 h 42 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$160 - $750
Flights from St. Louis to Indianapolis via Kansas City
Ave. Duration
3 h 45 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$190 - $800
Flights from St. Louis to Indianapolis via Atlanta
Ave. Duration
4 h 30 min
When
Sunday
Estimated price
$210 - $850
Flights from St. Louis to Indianapolis via Dallas
Ave. Duration
4 h 35 min
When
Sunday
Estimated price
$240 - $950
American Airlines
Website
aa.com
Flights from St. Louis to Indianapolis via Chicago O'Hare
Ave. Duration
3 h 43 min
When
Every day
Estimated price
$150 - $800
Flights from St. Louis to Indianapolis via Charlotte
Ave. Duration
4 h 30 min
When
Every day
Estimated price
$200 - $900
Delta
Website
delta.com
Flights from St. Louis to Indianapolis via Detroit
Ave. Duration
3 h 51 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$160 - $850
Flights from St. Louis to Indianapolis via Atlanta
Ave. Duration
4 h 17 min
When
Every day
Estimated price
$180 - $850
Bus operators
Greyhound USA
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from St Louis, Mo to Champaign, Il
Ave. Duration
3 h
Frequency
Hourly
Estimated price
$23 - $55
Website
greyhound.com
Economy
$23 - $35
Flexible
$40 - $55
Bus from St Louis, Mo to Terre Haute, In
Ave. Duration
4 h 15 min
Frequency
Every 4 hours
Estimated price
$22 - $55
Website
greyhound.com
Economy
$22 - $35
Flexible
$40 - $55
Burlington Trailways

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