There are 5 ways to get from St. Louis to Indianapolis by bus, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  6 h 20 min

  1. Take the bus from St Louis, Mo to Champaign, Il 1364 / ...
  2. Take the bus from Champaign, IL to Indianapolis, IN 1401 / ...

$53 - $104

Cheapest option

Bus via Terre Haute, In  •  6 h 41 min

  1. Take the bus from St Louis, Mo to Terre Haute, In 1684
  2. Take the bus from Terre Haute, IN to Indianapolis, IN Terre Haute

$43 - $81

3 alternative options

Train  •  11 h 34 min

  1. Take the train from St. Louis Gateway Station to Chicago Union Station Lincoln Service / ...
  2. Take the train from Chicago Union Station to Indianapolis Amtrak Hoosier State / ...

$91 - $228

Drive  •  4 h 6 min

  1. Drive from St. Louis to Indianapolis 243.1 miles

$23 - $35

Fly  •  5 h 24 min

  1. Fly from St. Louis (STL) to Indianapolis (IND) STL - IND

$154 - $804

Questions & Answers

The cheapest way to get from St. Louis to Indianapolis is to drive which costs $23 - $35 and takes 4 h 6 min.

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The quickest way to get from St. Louis to Indianapolis is to drive which costs $23 - $35 and takes 4 h 6 min.

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No, there is no direct bus from St. Louis to Indianapolis. However, there are services departing from St Louis, Mo and arriving at Indianapolis, IN via Champaign, IL. The journey, including transfers, takes approximately 6 h 20 min.

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No, there is no direct train from St. Louis station to Indianapolis. However, there are services departing from St. Louis Gateway Station and arriving at Indianapolis Amtrak via Chicago Union Station. The journey, including transfers, takes approximately 11 h 34 min.

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The distance between St. Louis and Indianapolis is 232 miles. The road distance is 243.1 miles.

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The best way to get from St. Louis to Indianapolis without a car is to bus which takes 6 h 20 min and costs $50 - $110.

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It takes approximately 6 h 20 min to get from St. Louis to Indianapolis, including transfers.

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St. Louis to Indianapolis bus services, operated by Greyhound USA, depart from St Louis, Mo station.

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St. Louis to Indianapolis train services, operated by Amtrak, arrive at St. Louis Gateway Station.

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The best way to get from St. Louis to Indianapolis is to bus which takes 6 h 20 min and costs $50 - $110. Alternatively, you can train, which costs $90 - $230 and takes 11 h 34 min, you could also fly, which costs $150 - $850 and takes 5 h 24 min.

Mode details

Map of how to get from St. Louis to Indianapolis.
Launch map view
  • Distance: 231.6 miles
  • Duration: 6 h 20 min

What companies run services between St. Louis, MO, USA and Indianapolis, IN, USA?

You can take a bus from St. Louis to Indianapolis via Champaign, Il and Champaign, IL in around 6 h 20 min. Alternatively, you can take a train from St. Louis to Indianapolis via Chicago Union Station in around 11 h 34 min.

Airlines
Delta
Website
delta.com
Flights from St. Louis to Indianapolis via Detroit
Ave. Duration
3 h 51 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$160 - $850
Flights from St. Louis to Indianapolis via Atlanta
Ave. Duration
4 h 17 min
When
Every day
Estimated price
$180 - $850
Flights from St. Louis to Indianapolis via Minneapolis
Ave. Duration
4 h 45 min
When
Every day
Estimated price
$180 - $900
Southwest Airlines
Website
southwest.com
Flights from St. Louis to Indianapolis via Chicago Midway
Ave. Duration
3 h 23 min
When
Every day
Estimated price
$160 - $750
Flights from St. Louis to Indianapolis via Kansas City
Ave. Duration
4 h 10 min
When
Monday to Friday
Estimated price
$190 - $800
Flights from St. Louis to Indianapolis via Baltimore
Ave. Duration
4 h 35 min
When
Sunday
Estimated price
$240 - $950
Flights from St. Louis to Indianapolis via Dallas
Ave. Duration
4 h 50 min
When
Sunday
Estimated price
$240 - $950
United Airlines
Website
united.com
Flights from St. Louis to Indianapolis via Chicago O'Hare
Ave. Duration
3 h 48 min
When
Every day
Estimated price
$170 - $850
Flights from St. Louis to Indianapolis via Washington Dulles
Ave. Duration
4 h 41 min
When
Wednesday, Thursday, Saturday and Sunday
Estimated price
$210 - $950
American Airlines
Website
aa.com
Flights from St. Louis to Indianapolis via Chicago O'Hare
Ave. Duration
3 h 54 min
When
Every day
Estimated price
$150 - $800
Flights from St. Louis to Indianapolis via Charlotte
Ave. Duration
4 h 38 min
When
Every day
Estimated price
$200 - $900
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from St. Louis Gateway Station to Chicago Union Station
Ave. Duration
5 h 40 min
Frequency
Every 4 hours
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$90 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Train from Chicago Union Station to Indianapolis Amtrak
Ave. Duration
4 h 54 min
Frequency
Once daily
Estimated price
$40 - $100
Website
amtrak.com
Coach Seat
$40 - $60
Flexi Coach Seat
$70 - $110
Business Coach Seat
$70 - $100
Room
$200 - $280
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from St Louis, Mo to Champaign, Il
Ave. Duration
3 h
Frequency
Hourly
Estimated price
$23 - $55
Website
greyhound.com
Economy
$23 - $35
Flexible
$40 - $55
Bus from St Louis, Mo to Terre Haute, In
Ave. Duration
4 h 15 min
Frequency
Every 4 hours
Estimated price
$22 - $55
Website
greyhound.com
Economy
$22 - $35
Flexible
$40 - $55
Burlington Trailways
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Bus from Champaign-Urbana to Indianapolis
Ave. Duration
3 h 10 min
Frequency
Twice daily
Website
amtrak.com

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More Questions & Answers

There is no direct flight from St. Louis Airport to Indianapolis Airport. The quickest flight takes 2 h 50 min and has one stopover.

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St. Louis to Indianapolis bus services, operated by Burlington Trailways, arrive at Indianapolis, IN station.

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Indianapolis is 1 h ahead of St. Louis. It is currently 4:37 PM in St. Louis and 5:37 PM in Indianapolis.

St. Louis to Indianapolis train services, operated by Amtrak, arrive at Indianapolis Amtrak station.

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Yes, the driving distance between St. Louis to Indianapolis is 243 miles. It takes approximately 4 h 6 min to drive from St. Louis to Indianapolis.

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Southwest Airlines, United Airlines, American Airlines and Delta offer flights from St. Louis Airport to Indianapolis Airport.

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Book your St. Louis to Indianapolis train tickets online with Rome2rio.

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There are 243+ hotels available in Indianapolis. Prices start at $69 USD per night.

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The best way to get from St. Louis to St. Louis Airport is to train which takes 31 min and costs $3.

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