There are 6 ways to get from St. Louis to Gatlinburg by plane, taxi, car or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Knoxville, taxi  •  5 h 50 min

  1. Fly from St. Louis (STL) to Knoxville (TYS) STL - TYS
  2. Take a taxi from Knoxville to Gatlinburg

$402 - $1,342

Cheapest option

Bus, drive via Columbus, Oh  •  24 h 57 min

  1. Take the bus from St Louis, Mo to Columbus, Oh
  2. Take the bus from Columbus, Oh to Winston Salem, Nc
  3. Take the bus from Winston Salem, Nc to Asheville, Nc
  4. Drive from Asheville, Nc to Gatlinburg

$112 - $278

4 alternative options

Fly to Asheville, drive  •  6 h 50 min

  1. Fly from St. Louis (STL) to Asheville (AVL) STL - AVL
  2. Drive from Asheville to Gatlinburg

$220 - $1,116

Fly to Tri-Cities Regional, drive  •  6 h 50 min

  1. Fly from St. Louis (STL) to Tri-Cities Regional (TRI) STL - TRI
  2. Drive from Tri-Cities Regional to Gatlinburg

$212 - $1,018

Bus, drive  •  26 h 37 min

  1. Take the bus from St Louis, Mo to Atlanta, Ga
  2. Take the bus from Atlanta, Ga to Winston Salem, Nc
  3. Take the bus from Winston Salem, Nc to Asheville, Nc
  4. Drive from Asheville, Nc to Gatlinburg

$120 - $285

Drive  •  8 h 48 min

  1. Drive from St. Louis to Gatlinburg 528.7 miles

$50 - $75

Questions & Answers

The distance between St. Louis and Gatlinburg is 422 miles. The road distance is 528.7 miles.

Get driving directions

It takes approximately 5 h 50 min to get from St. Louis to Gatlinburg, including transfers.

More details

There is no direct flight from St. Louis Airport to Knoxville Airport. The quickest flight takes 3 h 15 min and has one stopover.

Search flights

Gatlinburg is 1 h ahead of St. Louis. It is currently 9:09 PM in St. Louis and 10:09 PM in Gatlinburg.

Yes, the driving distance between St. Louis to Gatlinburg is 529 miles. It takes approximately 8 h 48 min to drive from St. Louis to Gatlinburg.

Get driving directions

United Airlines, American Airlines and Delta offer flights from St. Louis Airport to Knoxville Airport.

Search flights

There are 2119+ hotels available in Gatlinburg. Prices start at $65 USD per night.

More details

The best way to get from St. Louis to St. Louis Airport is to train which takes 31 min and costs .

More details

Map of how to get from St. Louis to Gatlinburg.
Launch map view
  • Distance: 421.9 miles
  • Duration: 5 h 50 min

What companies run services between St. Louis, MO, USA and Gatlinburg, TN, USA?

There is no direct connection from St. Louis to Gatlinburg. However, you can take the train to LAMBERT MAIN TRML station, take the walk to St. Louis airport, fly to Knoxville, then take the taxi to Gatlinburg. Alternatively, you can take the train to LAMBERT MAIN TRML station, take the walk to St. Louis airport, fly to Asheville, then take the drive to Gatlinburg.

Airlines
Delta
Website
delta.com
Flights from St. Louis to Knoxville via Atlanta
Ave. Duration
3 h 39 min
When
Every day
Estimated price
$200 - $1,100
Flights from St. Louis to Knoxville via Detroit
Ave. Duration
4 h 23 min
When
Every day
Estimated price
$220 - $1,100
Flights from St. Louis to Knoxville via Minneapolis
Ave. Duration
5 h 13 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$250 - $1,200
Flights from St. Louis to Asheville via Atlanta
Ave. Duration
4 h 14 min
When
Every day
Estimated price
$210 - $1,100
Flights from St. Louis to Asheville via Covington, Atlanta
Ave. Duration
6 h 55 min
When
Monday to Friday
Estimated price
$220 - $1,100
Flights from St. Louis to Tri-Cities Regional via Atlanta
Ave. Duration
4 h 48 min
When
Every day
Estimated price
$200 - $1,000
Flights from St. Louis to Tri-Cities Regional via Covington, Atlanta
Ave. Duration
6 h 50 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $1,100
American Airlines
Website
aa.com
Flights from St. Louis to Knoxville via Charlotte
Ave. Duration
3 h 57 min
When
Every day
Estimated price
$230 - $1,100
Flights from St. Louis to Knoxville via Chicago O'Hare
Ave. Duration
3 h 55 min
When
Every day
Estimated price
$220 - $1,100
Flights from St. Louis to Knoxville via Dallas/Ft.Worth
Ave. Duration
5 h 1 min
When
Every day
Estimated price
$280 - $1,200
Flights from St. Louis to Asheville via Charlotte
Ave. Duration
4 h 11 min
When
Every day
Estimated price
$220 - $1,100
Flights from St. Louis to Asheville via Reagan Washington, Charlotte
Ave. Duration
6 h 47 min
When
Monday and Tuesday
Estimated price
$270 - $1,200
Flights from St. Louis to Asheville via Philadelphia, Charlotte
Ave. Duration
7 h 10 min
When
Monday, Tuesday and Saturday
Estimated price
$290 - $1,200
Flights from St. Louis to Tri-Cities Regional via Charlotte
Ave. Duration
4 h 25 min
When
Every day
Estimated price
$210 - $1,000
Flights from St. Louis to Tri-Cities Regional via Chicago O'Hare, Charlotte
Ave. Duration
6 h 52 min
When
Every day
Estimated price
$240 - $1,100
United Airlines
Website
united.com
Flights from St. Louis to Knoxville via Chicago O'Hare
Ave. Duration
4 h 44 min
When
Every day
Estimated price
$240 - $1,100
Flights from St. Louis to Knoxville via Washington Dulles
Ave. Duration
4 h 49 min
When
Every day
Estimated price
$270 - $1,200
Flights from St. Louis to Asheville via Chicago O'Hare
Ave. Duration
4 h 43 min
When
Every day
Estimated price
$250 - $1,200
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from St Louis, Mo to Columbus, Oh
Ave. Duration
8 h 5 min
Frequency
Every 30 minutes
Estimated price
$40 - $110
Website
greyhound.com
Economy
$40 - $70
Flexible
$80 - $110
Bus from Columbus, Oh to Winston Salem, Nc
Ave. Duration
10 h 35 min
Frequency
Hourly
Estimated price
$40 - $110
Website
greyhound.com
Economy
$40 - $70
Flexible
$80 - $110
Bus from Winston Salem, Nc to Asheville, Nc
Ave. Duration
2 h 55 min
Frequency
Every 2 hours
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $30
Flexible
$35 - $50
Bus from St Louis, Mo to Atlanta, Ga
Ave. Duration
13 h 40 min
Frequency
Every 4 hours
Estimated price
$55 - $140
Website
greyhound.com
Economy
$55 - $90
Flexible
$100 - $140
Bus from Atlanta, Ga to Winston Salem, Nc
Ave. Duration
6 h 40 min
Frequency
Hourly
Estimated price
$35 - $85
Website
greyhound.com
Economy
$35 - $55
Flexible
$65 - $85
Other operators
Taxi from Knoxville to Gatlinburg
Ave. Duration
1 h 4 min
Estimated price
$200 - $240
Knoxville Taxi Service
Phone
+1 865 691 1900
Website
knoxvilletaxicab.com

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