There are 4 ways to get from St. Louis to Fort Wayne by bus (Greyhound), car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from St Louis Bus Station to Indianapolis Union Stationbus Greyhound US0421
- Take the bus from Indianapolis to Fort Waynebus Bsb 14
8h 43m$59–118Drive 365.1 mi
- Drive from St. Louis to Fort Waynecar 365.1 mi
6h 9m$63–91Fly
- Fly from Lambert–St. Louis International Airport (STL) to Fort Wayne International Airport (FWA)plane STL - FWA
5h 33m$102–458Bus via Coldwater at Stratton (Greyhound)
- Take the bus from St Louis Bus Station to Indianapolis Union Stationbus Greyhound US0421
- Take the bus from Indianapolis Union Station to Ft Wayne Citilink Central Stationbus Greyhound US0112
8h 51m$69–103
St. Louis to Fort Wayne by bus
Comparing Your Travel Options
The cheapest way to get from St. Louis to Fort Wayne is to drive which costs $60 - $90 and takes 6h 9m.
The fastest way to get from St. Louis to Fort Wayne is to fly which takes 5h 33m and costs $100 - $460.
No, there is no direct bus from St. Louis station to Fort Wayne. However, there are services departing from St Louis Bus Station and arriving at Coldwater at Northeast via Indianapolis and Central Station - Bay A. The journey, including transfers, takes approximately 8h 43m.
The distance between St. Louis and Fort Wayne is 372 miles. The road distance is 367.2 miles.
The best way to get from St. Louis to Fort Wayne without a car is to bus which takes 8h 43m and costs $55 - $120.
It takes approximately 8h 43m to get from St. Louis to Fort Wayne, including transfers.
St. Louis to Fort Wayne bus services, operated by Greyhound USA, depart from St Louis Bus Station.
The best way to get from St. Louis to Fort Wayne is to bus which takes 8h 43m and costs $55 - $120. Alternatively, you can fly, which costs $100 - $460 and takes 5h 33m.
St. Louis to Fort Wayne bus services, operated by Greyhound USA, arrive at Indianapolis Union Station.
Fort Wayne is 1h ahead of St. Louis. It is currently 7:17 PM in St. Louis and 8:17 PM in Fort Wayne.
What companies run services between St. Louis, MO, USA and Fort Wayne, IN, USA?
You can take a bus from St Louis Bus Station to Coldwater at Northeast via Indianapolis, Fort Wayne, and Central Station - Bay A in around 8h 43m. Alternatively, United Airlines, American Airlines, and Delta fly from Lambert–St. Louis International Airport (STL) to Fort Wayne International Airport (FWA) hourly.
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Fort Wayne International Airport via Chicago O'Hare
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $65–410
Flights from Lambert–St. Louis International Airport to Fort Wayne International Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 24m
- When
- Every day
- Estimated price
- $130–650
Flights from Lambert–St. Louis International Airport to Fort Wayne International Airport via Charlotte
- Ave. Duration
- 7h 7m
- When
- Every day
- Estimated price
- $110–550
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Fort Wayne International Airport via Chicago O'Hare
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $65–410
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Fort Wayne International Airport via Atlanta
- Ave. Duration
- 4h 30m
- When
- Every day
- Estimated price
- $100–550
Flights from Lambert–St. Louis International Airport to Fort Wayne International Airport via Detroit
- Ave. Duration
- 5h 35m
- When
- Every day
- Estimated price
- $75–440
Flights from Lambert–St. Louis International Airport to Fort Wayne International Airport via Minneapolis
- Ave. Duration
- 5h 49m
- When
- Every day
- Estimated price
- $100–550
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from St Louis Bus Station to Indianapolis Union Station
- Ave. Duration
- 4h 45m
- Frequency
- Every 4 hours
- Estimated price
- $45–70
- Website
- Greyhound
Bus from St Louis Bus Station to Indianapolis Union Station
- Ave. Duration
- 4h 45m
- Frequency
- Every 4 hours
- Estimated price
- $45–70
- Website
- Greyhound
Bus from Indianapolis Union Station to Ft Wayne Citilink Central Station
- Ave. Duration
- 2h 15m
- Frequency
- Twice daily
- Estimated price
- $22–35
- Website
- Greyhound
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- Barons Bus
Bus from Indianapolis to Fort Wayne
- Ave. Duration
- 2h 10m
- Frequency
- Once daily
- Estimated price
- $12–50
- Website
- Barons Bus
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Booking & Getting There
Yes, the driving distance between St. Louis to Fort Wayne is 367 miles. It takes approximately 6h 9m to drive from St. Louis to Fort Wayne.
Book your St. Louis to Fort Wayne bus tickets online with Omio.
There are 90+ hotels available in Fort Wayne.