There are 7 ways to get from St. Louis to Destin by plane, taxi, bus, train, night bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly St. Louis to Valparaiso  •  5 h 47 min

  1. Fly from St. Louis (STL) to Valparaiso (VPS) STL - VPS

$262 - $1,158

Cheapest option

Bus  •  23 h 48 min

  1. Take the bus from St Louis, Mo to Tallahassee, Fl 1167
  2. Take the bus from Tallahassee, Fl to Ft Walton Beach, Fl 1243 / ...

$132 - $296

5 alternative options

Fly St. Louis to Panama City, taxi  •  4 h 23 min

  1. Fly from St. Louis (STL) to Panama City (ECP) STL - ECP
  2. Take a taxi from Panama City to Destin

$372 - $1,452

Fly St. Louis to Pensacola, bus  •  7 h 6 min

  1. Fly from St. Louis (STL) to Pensacola (PNS) STL - PNS
  2. Take the bus from Pensacola, Fl to Ft Walton Beach, Fl

$202 - $508

Train to Belleville, fly to Valparaiso  •  5 h 6 min

  1. Take the train from CONVENTION CENTER station to SHILOH-SCOTT station
  2. Fly from Belleville (BLV) to Valparaiso (VPS) BLV - VPS

$140 - $400

Night bus, train, bus  •  23 h 48 min

  1. Take the night bus from St Louis, Mo to Carbondale
  2. Take the train from Carbondale Amtrak to New Orleans Union Passenger Terminal Amtrak
  3. Take the bus from New Orleans, La to Ft Walton Beach, Fl

$153 - $391

Drive  •  13 h 10 min

  1. Drive from St. Louis to Destin 761 miles

$70 - $110

Questions & Answers

The cheapest way to get from St. Louis to Destin is to drive which costs $70 - $110 and takes 13 h 10 min.

More details

The quickest way to get from St. Louis to Destin is to fly and taxi which costs $370 - $1,500 and takes 4 h 23 min.

More details

The distance between St. Louis and Destin is 610 miles. The road distance is 761 miles.

Get driving directions

It takes approximately 5 h 47 min to get from St. Louis to Destin, including transfers.

More details

What companies run services between St. Louis, MO, USA and Destin, FL, USA?

Delta, American Airlines and United Airlines fly from St. Louis to Destin hourly. Alternatively, you can take a bus from St. Louis to Destin via Tallahassee, Fl and Ft Walton Beach, Fl in around 23 h 48 min.

Airlines
Delta
Website
delta.com
Flights from St. Louis to Valparaiso via Atlanta
Ave. Duration
4 h 10 min
When
Every day
Estimated price
$220 - $1,100
Flights from St. Louis to Panama City via Atlanta
Ave. Duration
4 h 2 min
When
Every day
Estimated price
$250 - $1,300
Flights from St. Louis to Pensacola via Atlanta
Ave. Duration
4 h 50 min
When
Every day
Estimated price
$350 - $1,100
Southwest Airlines
Website
southwest.com
Flights from St. Louis to Panama City
Ave. Duration
1 h 43 min
When
Every day
Estimated price
$280 - $1,200
Flights from St. Louis to Pensacola via Nashville
Ave. Duration
4 h 45 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$450 - $800
Flights from St. Louis to Pensacola via Chicago Midway
Ave. Duration
5 h 35 min
When
Saturday and Sunday
Estimated price
$450 - $800
Flights from St. Louis to Pensacola via Kansas City
Ave. Duration
7 h 30 min
When
Saturday
Estimated price
$450 - $800
American Airlines
Website
aa.com
Flights from St. Louis to Valparaiso via Charlotte
Ave. Duration
5 h 22 min
When
Every day
Estimated price
$270 - $1,200
Flights from St. Louis to Valparaiso via Dallas/Ft.Worth
Ave. Duration
5 h 29 min
When
Every day
Estimated price
$280 - $1,200
United Airlines
Website
united.com
Flights from St. Louis to Valparaiso via Houston
Ave. Duration
5 h 1 min
When
Every day
Estimated price
$290 - $1,300
Allegiant Air
Website
allegiantair.com
Flights from Belleville to Valparaiso
Ave. Duration
1 h 43 min
When
Every day
Estimated price
$95 - $340
Train operators
Metro St. Louis
Phone
+1 314-982-1400
Website
metrostlouis.org
Train from CONVENTION CENTER station to SHILOH-SCOTT station
Ave. Duration
38 min
Frequency
Every 20 minutes
Estimated price
$3
Schedules at
metrostlouis.org
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Carbondale Amtrak to New Orleans Union Passenger Terminal Amtrak
Ave. Duration
14 h 21 min
Frequency
Once daily
Estimated price
$85 - $250
Website
amtrak.com
Coach Seat
$85 - $130
Flexi Coach Seat
$150 - $230
Business Coach Seat
$170 - $250
Room
$370 - $550
Bus operators
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Pensacola, Fl to Ft Walton Beach, Fl
Ave. Duration
1 h 10 min
Frequency
Every 30 minutes
Estimated price
$11 - $26
Website
greyhound.com
Economy
$11 - $17
Flexible
$20 - $26
Night bus from St Louis, Mo to Carbondale
Ave. Duration
1 h 55 min
Frequency
Hourly
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $24
Flexible
$29 - $40
Bus from New Orleans, La to Ft Walton Beach, Fl
Ave. Duration
6 h
Frequency
Hourly
Estimated price
$29 - $75
Website
greyhound.com
Economy
$29 - $50
Flexible
$55 - $75
Bus from St Louis, Mo to Tallahassee, Fl
Ave. Duration
20 h 25 min
Frequency
Every 3 hours
Estimated price
$85 - $220
Website
greyhound.com
Economy
$85 - $150
Flexible
$160 - $220
Bus from Tallahassee, Fl to Ft Walton Beach, Fl
Ave. Duration
3 h 5 min
Frequency
Every 15 minutes
Estimated price
$21 - $50
Website
greyhound.com
Economy
$21 - $35
Flexible
$35 - $50
Other operators
Taxi from Panama City to Destin
Ave. Duration
1 h 12 min
Estimated price
$120 - $150
Red Cabs of Panama City
Phone
+1 850-733-2227
Website
myfloridacabs.com
H2O Shuttle Taxi and Limo
Phone
+1 850-708-2870
Emerald Taxi
Phone
+1 850-792-2546
Website
emeraldtaxiandshuttle.com

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