There are 5 ways to get from St. Louis to Clemson by plane, taxi, bus, train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Greenville–Spartanburg International Airport, taxi
best- Fly from Lambert–St. Louis International Airport (STL) to Greenville–Spartanburg International Airport (GSP)plane STL - GSP
- Take the taxi from Greenville–Spartanburg International Airport (GSP) to Clemsontaxi
5h 50m$222–882Drive 618.3 mi
cheapest- Drive from St. Louis to Clemsoncar 618.3 mi
11h$113–163Bus, taxi
- Take the bus from St Louis Bus Station to Atlanta Bus Stationbus
- Take the bus from Atlanta to Flying J - Commercebus
- Take the taxi from Flying J - Commerce to Clemsontaxi
15h 29m$204–411Train (Amtrak)
- Take the train from St. Louis to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Charlottesvilletrain
- Take the train from Charlottesville to Clemson Amtrak Stationtrain
36h 50m$272–1,162Fly to Asheville Regional Airport, drive
- Fly from Lambert–St. Louis International Airport (STL) to Asheville Regional Airport (AVL)plane STL - AVL
- Drive from Asheville-Airport-AVL to Clemsoncar
7h 1m$116–622
St. Louis to Clemson by train (Amtrak)
Questions & Answers
The cheapest way to get from St. Louis to Clemson is to drive which costs $110 - $170 and takes 11h.
The fastest way to get from St. Louis to Clemson is to fly and taxi which takes 5h 50m and costs $220 - $900.
No, there is no direct train from St. Louis to Clemson station. However, there are services departing from St. Louis and arriving at Clemson Amtrak Station via Chicago Union Station and Charlottesville. The journey, including transfers, takes approximately 36h 50m.
The distance between St. Louis and Clemson is 583 miles. The road distance is 621.9 miles.
The best way to get from St. Louis to Clemson without a car is to bus and taxi which takes 15h 29m and costs $200 - $420.
It takes approximately 5h 50m to get from St. Louis to Clemson, including transfers.
St. Louis to Clemson train services, operated by Amtrak, depart from St. Louis station.
Clemson is 1h ahead of St. Louis. It is currently 2:08 AM in St. Louis and 3:08 AM in Clemson.
St. Louis to Clemson train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between St. Louis to Clemson is 622 miles. It takes approximately 11h to drive from St. Louis to Clemson.
What companies run services between St. Louis, MO, USA and Clemson, SC, USA?
You can take a train from St. Louis to Clemson Amtrak Station via Chicago Union Station and Charlottesville in around 36h 50m.
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Greenville–Spartanburg International Airport via Charlotte
- Ave. Duration
- 4h 3m
- When
- Every day
- Estimated price
- $140–800
Flights from Lambert–St. Louis International Airport to Greenville–Spartanburg International Airport via Chicago O'Hare
- Ave. Duration
- 4h 27m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $160–850
Flights from Lambert–St. Louis International Airport to Asheville Regional Airport via Charlotte
- Ave. Duration
- 4h 34m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $100–600
Flights from Lambert–St. Louis International Airport to Asheville Regional Airport via Reagan Washington
- Ave. Duration
- 6h 46m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $140–700
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Greenville–Spartanburg International Airport via Atlanta
- Ave. Duration
- 4h 14m
- When
- Every day
- Estimated price
- $140–800
Flights from Lambert–St. Louis International Airport to Greenville–Spartanburg International Airport via Detroit
- Ave. Duration
- 6h 21m
- When
- Thursday and Friday
- Estimated price
- $170–900
Flights from Lambert–St. Louis International Airport to Asheville Regional Airport via Atlanta
- Ave. Duration
- 4h 46m
- When
- Every day
- Estimated price
- $100–600
Flights from Lambert–St. Louis International Airport to Asheville Regional Airport via Minneapolis
- Ave. Duration
- 4h 56m
- When
- Monday, Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- $160–750
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Greenville–Spartanburg International Airport via Chicago O'Hare
- Ave. Duration
- 4h 33m
- When
- Saturday and Sunday
- Estimated price
- $160–850
Flights from Lambert–St. Louis International Airport to Asheville Regional Airport via Chicago O'Hare
- Ave. Duration
- 4h 40m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–600
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Greenville–Spartanburg International Airport via Nashville
- Ave. Duration
- 5h 22m
- When
- Thursday to Saturday
- Estimated price
- $120–750
Flights from Lambert–St. Louis International Airport to Greenville–Spartanburg International Airport via Baltimore
- Ave. Duration
- 5h 35m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $200–1,000
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- $40–320
- Website
- https://www.amtrak.com/home.html
Train from Chicago Union Station to Charlottesville
- Ave. Duration
- 20h 40m
- Frequency
- 3 times a week
- Estimated price
- $190–700
- Website
- https://www.amtrak.com/home.html
Train from Charlottesville to Clemson Amtrak Station
- Ave. Duration
- 9h 15m
- Frequency
- Once daily
- Estimated price
- $40–150
- Website
- https://www.amtrak.com/home.html
- Coach Seat - Advance Purchase
- $40–100
- Coach Seat short notice purchase
- $50–150
- Business - advance purchase
- $70–310
- Business Class
- $110–340
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from St Louis Bus Station to Atlanta Bus Station
- Ave. Duration
- 10h 30m
- Frequency
- Once daily
- Estimated price
- $55–140
- Schedules at
- flixbus.com
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from Atlanta to Flying J - Commerce
- Ave. Duration
- 1h 52m
- Frequency
- Once daily
- Estimated price
- $40–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–140
- Ave. Duration
- 56 min
- Estimated price
- $100–130
Yellow Cab Greenville
- Phone
- +1 864-233-6666
- Website
- yellowcabgreenville.com
Corporate Taxi
- Phone
- +1 864-990-5556
- Website
- ataxi.co
Atlantis Taxi
- Phone
- +1 850-628-5670
- Website
- facebook.com
Checker Cab
- Phone
- +1 864-583-2721
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
More Questions & Answers
Book your St. Louis to Clemson train tickets online with Omio.
There are 105+ hotels available in Clemson.










