Rome2Rio

How to get fromSt. Louis to Cincinnatiby plane, bus (Greyhound), car, or bus

Find Transport to Cincinnati

See all options

There are 6 ways to get from St. Louis to Cincinnati by plane, bus (Greyhound), car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Covington

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Covington (CVG)plane plane STL - CVG
    5h 35m
    $604–954

  2. Bus

    cheapest
    1. Take the bus from St Louis Bus Station to Indianapolis Union Stationbus bus Greyhound US0421
    2. Take the bus from Indianapolis to Cincinnatibus bus Bsb 15 / ...
    9h 55m
    $53–141

  3. Drive  345.4 mi

    1. Drive from St. Louis to Cincinnaticar car 345.4 mi
    5h 48m
    $63–92

  4. Fly to Louisville International Airport, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Louisville International Airport (SDF)plane plane STL - SDF
    2. Drive from Louisville-Airport-SDF to Cincinnaticar car
    6h 28m
    $122–730

  5. Fly to Blue Grass Airport, drive

    1. Fly from Lambert–St. Louis International Airport (STL) to Blue Grass Airport (LEX)plane plane STL - LEX
    2. Drive from Lexington-Airport-LEX to Cincinnaticar car
    7h 2m
    $88–446

  6. Fly to John Glenn Columbus International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to John Glenn Columbus International Airport (CMH)plane plane STL - CMH
    2. Take the bus from Columbus to Cincinnatibus bus
    7h 28m
    $824–936

St. Louis to Cincinnati by bus

Calendar14Weekly Buses
Duration9h 55mAverage Duration
Ticket$53Cheapest Price
See schedules

Comparing Your Travel Options

Map of how to get from St. Louis to Cincinnati.ExpandLaunch map view
  • Distance: 335.3 mi
  • Duration: 5h 35m

What companies run services between St. Louis, MO, USA and Cincinnati, OH, USA?

Southwest Airlines, Delta, and two other airlines fly from Lambert–St. Louis International Airport (STL) to Covington (CVG) hourly. Alternatively, you can take a bus from St Louis Bus Station to Cincinnati via Indianapolis and Cincinnati in around 9h 55m.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Booking & Getting There