There are 7 ways to get from St. Louis to Chicago Loop by train (Amtrak), bus (Flixbus), car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train (Amtrak)
best- Take the train from St. Louis to Chicago Union StationLincoln Service / ...
4h 55m$40–130Bus (Flixbus)
- Take the bus from St Louis Bus Station to Chicago Bus StationFlixBus N2521 / ...
6h 29m$41–82Drive 293.2 mi
- Drive from St. Louis to Chicago Loop293.2 mi
5h 1m$54–78Fly Lambert–St. Louis International Airport to Chicago Midway International Airport
- Fly from Lambert–St. Louis International Airport (STL) to Chicago Midway International Airport (MDW)STL - MDW
3h 20m$74–498Fly Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Fly from Lambert–St. Louis International Airport (STL) to Chicago O'Hare International Airport (ORD)STL - ORD
3h 38m$134–488Drive to Decatur Airport, fly to Chicago O'Hare International Airport
- Drive from St. Louis to Decatur Airport (DEC)
- Fly from Decatur Airport (DEC) to Chicago O'Hare International Airport (ORD)DEC - ORD
4h 24m$54–267Train to Abraham Lincoln Capital Airport, fly to Chicago O'Hare International Airport
- Take the train from St. Louis to Springfield
- Fly from Abraham Lincoln Capital Airport (SPI) to Chicago O'Hare International Airport (ORD)SPI - ORD
4h 45m$63–299
St. Louis to Chicago Loop by train (Amtrak)
Questions & Answers
The cheapest way to get from St. Louis to Chicago Loop is to bus which costs $40 - $85 and takes 6h 29m.
The fastest way to get from St. Louis to Chicago Loop is to fly which takes 3h 20m and costs $70 - $500.
No, there is no direct bus from St. Louis station to Chicago Loop. However, there are services departing from St Louis Bus Station and arriving at Washington & Lasalle via Jefferson & Harrison. The journey, including transfers, takes approximately 6h 29m.
Yes, there is a direct train departing from St. Louis and arriving at Chicago Union Station station. Services depart five times a day, and operate every day. The journey takes approximately 4h 55m.
The distance between St. Louis and Chicago Loop is 282 miles. The road distance is 294.9 miles.
The best way to get from St. Louis to Chicago Loop without a car is to train which takes 4h 55m and costs $40 - $130.
The train from St. Louis to Chicago Union Station takes 4h 55m including transfers and departs five times a day.
St. Louis to Chicago Loop bus services, operated by Flixbus USA, depart from St Louis Bus Station.
St. Louis to Chicago Loop train services, operated by Amtrak, depart from St. Louis station.
The best way to get from St. Louis to Chicago Loop is to train which takes 4h 55m and costs $40 - $130. Alternatively, you can bus, which costs $40 - $85 and takes 6h 29m, you could also fly, which costs $70 - $500 and takes 3h 20m.
What companies run services between St. Louis, MO, USA and Chicago Loop, IL, USA?
Amtrak operates a train from St. Louis to Chicago Union Station 5 times a day. Tickets cost $40–130 and the journey takes 4h 55m. Alternatively, Flixbus USA operates a bus from St Louis Bus Station to Chicago Bus Station twice daily. Tickets cost $35–80 and the journey takes 6h 15m.
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- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 31m
- When
- Every day
- Estimated price
- $50–340
Flights from Abraham Lincoln Capital Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $30–230
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 9m
- When
- Every day
- Estimated price
- $70–490
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 28m
- When
- Every day
- Estimated price
- $50–340
Flights from Decatur Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 11m
- When
- Every day
- Estimated price
- $30–230
- Website
- gojetairlines.com
Flights from Lambert–St. Louis International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $50–340
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from St. Louis to Chicago Union Station
- Ave. Duration
- 4h 55m
- Frequency
- 5 times a day
- Estimated price
- $40–130
- Website
- https://www.amtrak.com/home.html
Train from St. Louis to Springfield
- Ave. Duration
- 1h 38m
- Frequency
- 5 times a day
- Estimated price
- $18–50
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from St Louis Bus Station to Chicago Bus Station
- Ave. Duration
- 6h 15m
- Frequency
- Twice daily
- Estimated price
- $35–80
- Schedules at
- flixbus.com
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More Questions & Answers
St. Louis to Chicago Loop bus services, operated by Flixbus USA, arrive at Chicago Bus Station.
St. Louis to Chicago Loop train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between St. Louis to Chicago Loop is 295 miles. It takes approximately 5h 1m to drive from St. Louis to Chicago Loop.
Book your St. Louis to Chicago Loop train tickets online with Omio.
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