There are 3 ways to get from St. Louis to Cape Girardeau by bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  2 h 9 min

  1. Take the bus from St Louis, Mo to Cape Girardeau, Mo 1138

$26 - $50

2 alternative options

Drive  •  1 h 58 min

  1. Drive from St. Louis to Cape Girardeau 116.2 miles

$11 - $17

Fly, drive  •  3 h 33 min

  1. Fly from St. Louis (STL) to Marion (MWA) STL - MWA
  2. Drive from Marion to Cape Girardeau

$36 - $86

Questions & Answers

The cheapest way to get from St. Louis to Cape Girardeau is to drive which costs $11 - $17 and takes 1 h 58 min.

More details

The quickest way to get from St. Louis to Cape Girardeau is to drive which costs $11 - $17 and takes 1 h 58 min.

More details

The distance between St. Louis and Cape Girardeau is 99 miles. The road distance is 116.2 miles.

Get driving directions

It takes approximately 2 h 9 min to get from St. Louis to Cape Girardeau, including transfers.

More details

What companies run services between St. Louis, MO, USA and Cape Girardeau, MO, USA?

Greyhound USA operates a bus from St. Louis to Cape Girardeau every 4 hours. Tickets cost $17 - $40 and the journey takes 2 h 5 min.

Airlines
Cape Air
Website
capeair.com
Flights from St. Louis to Marion
Ave. Duration
48 min
When
Every day
Estimated price
$29 - $100
Bus operators
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from St Louis, Mo to Cape Girardeau, Mo
Ave. Duration
2 h 5 min
Frequency
Every 4 hours
Estimated price
$17 - $40
Website
greyhound.com
Economy
$17 - $26
Flexible
$30 - $40

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