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How to get fromSt. Louis to Appletonby plane, train, bus, bus (Flixbus) or car

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There are 7 ways to get from St. Louis to Appleton by plane, train, bus, bus (Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Appleton International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to Appleton International Airport (ATW)plane plane STL - ATW
    5h 5m
    $96–506

  2. Bus (Flixbus)

    cheapest
    1. Take the bus from St Louis Bus Station to Chicago Bus Stationbus bus FlixBus N2521 / ...
    2. Take the bus from Chicago Bus Station to Appleton Transit Centerbus bus FlixBus 2550
    11h 45m
    $60–104

  3. Train, bus

    1. Take the train from St. Louis to Chicago Union Stationtrain train Lincoln Service / ...
    2. Take the bus from Chicago Bus Station to Appleton Transit Centerbus bus FlixBus 2550
    10h 34m
    $85–183

  4. Drive 442.3 mi

    1. Drive from St. Louis to Appletoncar car 442.3 mi
    7h 36m
    $81–117

  5. Fly to Green Bay

    1. Fly from Lambert–St. Louis International Airport (STL) to Green Bay (GRB)plane plane STL - GRB
    6h 33m
    $112–536

  6. Fly to General Mitchell International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to General Mitchell International Airport (MKE)plane plane STL - MKE
    2. Take the bus from Milwaukee Airport Amtrak Bus Stop to Appleton Amtrak Stationbus bus
    6h 39m
    $156–1,008

  7. Train, bus via Milwaukee

    1. Take the train from St. Louis to Chicago Union Stationtrain train
    2. Take the train from Chicago Union Station to Milwaukeetrain train
    3. Take the bus from Milwaukee to Appleton Amtrak Stationbus bus
    10h 48m
    $94–238

St. Louis to Appleton by train, foot, and bus

Calendar5Weekly Services
Duration10h 34mAverage Duration
Ticket$85Cheapest Price
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Questions & Answers

What companies run services between St. Louis, MO, USA and Appleton, WI, USA?

American Airlines, United Airlines, and Delta fly from Lambert–St. Louis International Airport (STL) to Appleton International Airport (ATW) hourly. Alternatively, you can take a bus from St Louis Bus Station to Appleton Transit Center via Chicago Bus Station in around 11h 45m.

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