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There are 5 ways to get from St. Louis to Ames by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  4 h 7 min

  1. Fly from St. Louis (STL) to Des Moines (DSM) STL - DSM

$200 - $790

Cheapest option

Bus Greyhound USA  •  9 h 45 min

  1. Take the bus from St Louis, Mo to Kansas City, Mo 1683 / ...
  2. Take the bus from Kansas City, MO to Ames, IA 804 / ...

$74 - $133

3 alternative options

Train, bus  •  11 h 31 min

  1. Take the train from St. Louis Gateway Station to Kansas City Union Station
  2. Take the bus from Kansas City, MO to Des Moines, IA 802 / ...
  3. Take the bus from Des Moines, IA to Ames, IA 806 / ...

$110 - $208

Bus Burlington Trailways  •  13 h 35 min

  1. Take the bus from St Louis, MO to Cedar Rapids 1490
  2. Take the bus from Cedar Rapids,IA to Ames, IA 1485

$75 - $138

Drive  •  6 h 59 min

  1. Drive from St. Louis to Ames 380.7 miles

$35 - $55

Questions & Answers

The cheapest way to get from St. Louis to Ames is to drive which costs $35 - $55 and takes 6 h 59 min.

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The quickest way to get from St. Louis to Ames is to fly which costs $200 - $800 and takes 4 h 7 min.

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No, there is no direct bus from St. Louis to Ames. However, there are services departing from St Louis, Mo and arriving at Ames, IA via Kansas City, MO. The journey, including transfers, takes approximately 9 h 45 min.

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The distance between St. Louis and Ames is 298 miles. The road distance is 380.7 miles.

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The best way to get from St. Louis to Ames without a car is to bus which takes 9 h 45 min and costs $70 - $140.

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It takes approximately 4 h 7 min to get from St. Louis to Ames, including transfers.

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St. Louis to Ames bus services, operated by Greyhound USA, depart from St Louis, Mo station.

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The best way to get from St. Louis to Ames is to fly which takes 4 h 7 min and costs $200 - $800. Alternatively, you can bus, which costs $70 - $140 and takes 9 h 45 min.

Mode details

The quickest flight from St. Louis Airport to Des Moines Airport is the direct flight which takes 1 h.

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St. Louis to Ames bus services, operated by Jefferson Lines, arrive at Ames, IA station.

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Map of how to get from St. Louis to Ames.
Launch map view
  • Distance: 298.2 miles
  • Duration: 4 h 7 min

What companies run services between St. Louis, MO, USA and Ames, IA, USA?

Southwest Airlines flies from St. Louis to Ames twice daily. Alternatively, you can take a bus from St. Louis to Ames via Kansas City, Mo and Kansas City, MO in around 9 h 45 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from St. Louis to Des Moines
Ave. Duration
1 h 4 min
When
Every day
Estimated price
$160 - $750
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from St. Louis Gateway Station to Kansas City Union Station
Ave. Duration
5 h 40 min
Frequency
Twice daily
Estimated price
$50 - $130
Website
amtrak.com
Coach Seat
$50 - $75
Flexi Coach Seat
$85 - $130
Business Coach Seat
$90 - $130
Room
$230 - $320
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from St Louis, Mo to Kansas City, Mo
Ave. Duration
4 h 25 min
Frequency
4 times a day
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $45
Flexible
$50 - $70
Jefferson Lines
Phone
800-451-5333
Email
info@jeffersonlines.com
Website
jeffersonlines.com
Bus from Kansas City, MO to Ames, IA
Ave. Duration
4 h 20 min
Frequency
3 times a day
Estimated price
$45 - $65
Book at
jeffersonlines.com
Bus from Kansas City, MO to Des Moines, IA
Ave. Duration
2 h 55 min
Frequency
3 times a day
Estimated price
$40 - $55
Book at
jeffersonlines.com
Bus from Des Moines, IA to Ames, IA
Ave. Duration
35 min
Frequency
3 times a day
Estimated price
$15 - $22
Book at
jeffersonlines.com
Burlington Trailways
Website
burlingtontrailways.com
Bus from St Louis, MO to Cedar Rapids
Ave. Duration
9 h 15 min
Frequency
Once daily
Estimated price
$45 - $100
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com
Bus from Cedar Rapids,IA to Ames, IA
Ave. Duration
3 h 15 min
Frequency
Once daily
Estimated price
$25 - $40
Schedules at
burlingtontrailways.com
Book at
burlingtontrailways.com

Want to know more about travelling around United States

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More Questions & Answers

Yes, the driving distance between St. Louis to Ames is 381 miles. It takes approximately 6 h 59 min to drive from St. Louis to Ames.

Get driving directions

Southwest Airlines offers flights from St. Louis Airport to Des Moines Airport.

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There are 24+ hotels available in Ames. Prices start at $71 USD per night.

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The best way to get from St. Louis to St. Louis Airport is to train which takes 31 min and costs $3.

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