There are 4 ways to get from St. Louis to Ames by bus (Greyhound), car, plane, shuttle, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from St Louis Bus Station to Des Moinesbus Greyhound US0153S
- Take the bus from Des Moines to Amesbus Jefferson 804 / ...
10h 5m$86–153Drive 361.6 mi
cheapest- Drive from St. Louis to Amescar 361.6 mi
7h 4m$66–96Fly to Des Moines, shuttle
- Fly from Lambert–St. Louis International Airport (STL) to Des Moines (DSM)plane STL - DSM
- Take a shuttle bus from Des Moines International Airport, IA to Ames, IA - Iowa State University
6h 41m$232–1,142Fly to Fort Dodge Municipal Airport, taxi
- Fly from Lambert–St. Louis International Airport (STL) to Fort Dodge Municipal Airport (FOD)plane STL - FOD
- Take the taxi from Fort Dodge Municipal Airport (FOD) to Amestaxi
7h 2m$222–662
St. Louis to Ames by bus
Questions & Answers
The cheapest way to get from St. Louis to Ames is to drive which costs $65 - $100 and takes 7h 4m.
The fastest way to get from St. Louis to Ames is to fly and shuttle which takes 6h 41m and costs $230 - $1,200.
No, there is no direct bus from St. Louis station to Ames. However, there are services departing from St Louis Bus Station and arriving at Ames via Des Moines. The journey, including transfers, takes approximately 10h 5m.
The distance between St. Louis and Ames is 449 miles. The road distance is 363.8 miles.
The best way to get from St. Louis to Ames without a car is to bus which takes 10h 5m and costs $85 - $160.
It takes approximately 10h 5m to get from St. Louis to Ames, including transfers.
St. Louis to Ames bus services, operated by Greyhound USA, depart from St Louis Bus Station.
St. Louis to Ames bus services, operated by Greyhound USA, arrive at Des Moines station.
Yes, the driving distance between St. Louis to Ames is 364 miles. It takes approximately 7h 4m to drive from St. Louis to Ames.
There are 37+ hotels available in Ames.
What companies run services between St. Louis, MO, USA and Ames, IA, USA?
You can take a bus from St Louis Bus Station to Ames via Des Moines in around 10h 5m.
- Website
- united.com
Flights from Lambert–St. Louis International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 20m
- When
- Every day
- Estimated price
- $150–950
Flights from Lambert–St. Louis International Airport to Des Moines via Denver
- Ave. Duration
- 5h 32m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $300–1,400
Flights from Lambert–St. Louis International Airport to Fort Dodge Municipal Airport via Chicago O'Hare
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $80–480
Flights from Lambert–St. Louis International Airport to Fort Dodge Municipal Airport via Denver
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $150–700
- Website
- delta.com
Flights from Lambert–St. Louis International Airport to Des Moines via Minneapolis
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $180–1,000
Flights from Lambert–St. Louis International Airport to Des Moines via Atlanta
- Ave. Duration
- 5h 54m
- When
- Every day
- Estimated price
- $280–1,400
Flights from Lambert–St. Louis International Airport to Des Moines via Detroit
- Ave. Duration
- 6h 33m
- When
- Every day
- Estimated price
- $230–1,200
- Website
- aa.com
Flights from Lambert–St. Louis International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 10m
- When
- Every day
- Estimated price
- $150–950
Flights from Lambert–St. Louis International Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 5h 39m
- When
- Every day
- Estimated price
- $270–1,300
- Website
- southwest.com
Flights from Lambert–St. Louis International Airport to Des Moines via Chicago Midway
- Ave. Duration
- 5h 33m
- When
- Every day
- Estimated price
- $150–950
Flights from Lambert–St. Louis International Airport to Des Moines via Denver
- Ave. Duration
- 6h 15m
- When
- Sunday
- Estimated price
- $300–1,400
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from St Louis Bus Station to Des Moines
- Ave. Duration
- 8h 25m
- Frequency
- Once daily
- Estimated price
- $65–130
- Website
- https://www.greyhound.com/
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Des Moines to Ames
- Ave. Duration
- 40 min
- Frequency
- Twice daily
- Estimated price
- $19–27
- Book at
- https://www.jeffersonlines.com
- Adult
- $19–27
- Phone
- +1 320.253.2226
- Website
- executiveexpress.biz
Shuttle from Des Moines International Airport, IA to Ames, IA - Iowa State University
- Ave. Duration
- 45 min
- Frequency
- On demand
- Estimated price
- $80–190
- Website
- https://www.executiveexpress.biz
- Schedules at
- https://www.executiveexpress.biz/coverage-areas/
- Ave. Duration
- 1h 21m
- Estimated price
- $140–180
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