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How to get fromSt. Louis Airport (STL) to San Diegoby plane, bus (Greyhound, Amtrak), train (Amtrak), car, bus or train

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There are 10 ways to get from St. Louis Airport (STL) to San Diego by plane, bus (Greyhound, Amtrak), train (Amtrak), car, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to San Diego International Airport

    best
    1. Fly from Lambert–St. Louis International Airport (STL) to San Diego International Airport (SAN)planeSTL - SAN
    4h 21m
    $363–484

  2. Fly to Tijuana International Airport

    cheapest
    1. Fly from Lambert–St. Louis International Airport (STL) to Tijuana International Airport (TIJ)planeSTL - TIJ
    8h 57m
    $136–624

  3. Bus

    1. Take the bus from Saint Louis to Los Angeles Union StationbusGreyhound US1210
    2. Take the bus from Los Angeles to San DiegobusAmtrak Thruway Connecting Service
    43h 15m

  4. Train via Kansas City (Amtrak)

    1. Take the train from St. Louis to Kansas Citytrain
    2. Take the train from Kansas City to Fullerton Amtrak Stationtrain
    3. Take the train from Fullerton Amtrak Station to San Diegotrain
    46h 26m
    $220–736

  5. Drive 1,796.2 mi

    1. Drive from St. Louis Airport (STL) to San Diegocar1,796.2 mi
    29h 10m
    $328–474

  6. Fly to Los Angeles International Airport, bus

    1. Fly from Lambert–St. Louis International Airport (STL) to Los Angeles International Airport (LAX)planeSTL - LAX
    2. Take the bus from LAX Terminal 3 Shared Rides Stop to San Diegobus
    7h 53m
    $285–735

  7. Fly to Mcclellan–Palomar Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Mcclellan–Palomar Airport (CLD)planeSTL - CLD
    2. Take the train from Carlsbad Village Station to San Diego - Santa Fe Depottrain
    10h 7m
    $177–767

  8. Fly to Burbank Bob Hope Airport, train

    1. Fly from Lambert–St. Louis International Airport (STL) to Burbank Bob Hope Airport (BUR)planeSTL - BUR
    2. Take the train from Los Angeles to San Diegotrain
    9h 45m
    $432–838

  9. Fly to John Wayne Airport Orange County, train

    1. Fly from Lambert–St. Louis International Airport (STL) to John Wayne Airport Orange County (SNA)planeSTL - SNA
    2. Take the train from Fullerton Amtrak Station to San Diegotrain
    11h 41m
    $236–906

  10. Train (Amtrak)

    1. Take the train from St. Louis to Los AngelestrainTexas Eagle
    2. Take the train from Los Angeles to San DiegotrainPacific Surfliner
    2d 17h
    $216–592

Lambert–St. Louis International Airport (STL) to San Diego International Airport (SAN) flights

Calendar54Weekly Planes
Duration5h 17mAverage Duration
Ticket$203Cheapest Price
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Questions & Answers

What companies run services between St. Louis Airport (STL), USA and San Diego, CA, USA?

Southwest Airlines and United Airlines fly from Lambert–St. Louis International Airport (STL) to San Diego International Airport (SAN) every 4 hours. Alternatively, you can take a bus from Saint Louis to San Diego via Los Angeles Union Station and Los Angeles in around 43h 15m.

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