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There are 5 ways to get from St. Louis Airport (STL) to La Crosse by plane, train, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  3h 59m

  1. Fly from St. Louis (STL) to La Crosse (LSE) STL - LSE

$216 - $1,013

Cheapest option

Bus via Madison  •  15h 21m

  1. Take the bus from St. Louis to Chicago, IL
  2. Take the bus from Chicago to Madison - Langdon & N Park
  3. Take the bus from Madison, WI - Chazen UW Madison to La Crosse, WI - UW La Crosse - Sanford Hall

$72 - $106

3 alternative options

Train  •  13h 7m

  1. Take the train from St. Louis Gateway Station to Chicago Union Station Lincoln Service / ...
  2. Take the train from Chicago Union Station to La Crosse Amtrak Station Empire Builder

$82 - $122

Bus  •  15h 59m

  1. Take the bus from St Louis, Mo to Chicago, Il
  2. Take the bus from Chicago, Il to Milwaukee, Wi
  3. Take the bus from Milwaukee to La Crosse 966

$98 - $150

Drive  •  8h 14m

  1. Drive from St. Louis Airport (STL) to La Crosse 428.7 miles

$40 - $65

Questions & Answers

The cheapest way to get from St. Louis Airport (STL) to La Crosse is to drive which costs $40 - $65 and takes 8h 14m.

More details

The quickest way to get from St. Louis Airport (STL) to La Crosse is to fly which costs $210 - $1,100 and takes 3h 59m.

More details

No, there is no direct bus from St. Louis Airport (STL) to La Crosse. However, there are services departing from St Louis Lambert Fld and arriving at La Crosse via St Louis, Mo, Chicago, Il and Milwaukee. The journey, including transfers, takes approximately 15h 59m.

More details

No, there is no direct train from St. Louis Airport (STL) station to La Crosse station. However, there are services departing from LAMBERT MAIN TRML station and arriving at La Crosse Amtrak Station via St. Louis Gateway Station and Chicago Union Station. The journey, including transfers, takes approximately 13h 7m.

More details

The distance between St. Louis Airport (STL) and La Crosse is 355 miles. The road distance is 428.7 miles.

Get driving directions

The best way to get from St. Louis Airport (STL) to La Crosse without a car is to train which takes 13h 7m and costs $80 - $130.

More details

It takes approximately 3h 59m to get from St. Louis Airport (STL) to La Crosse, including transfers.

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St. Louis Airport (STL) to La Crosse bus services, operated by Greyhound USA, depart from St Louis, Mo station.

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St. Louis Airport (STL) to La Crosse train services, operated by Amtrak, arrive at St. Louis Gateway Station.

More details

The best way to get from St. Louis Airport (STL) to La Crosse is to fly which takes 3h 59m and costs $210 - $1,100. Alternatively, you can train, which costs $80 - $130 and takes 13h 7m, you could also bus via Madison, which costs $70 - $110 and takes 15h 21m.

Mode details

Map of how to get from St. Louis Airport (STL) to La Crosse.
Launch map view
  • Distance: 354.5 miles
  • Duration: 3h 59m

What companies run services between St. Louis Airport (STL), USA and La Crosse, WI, USA?

Delta, American Airlines and two other airlines fly from St. Louis Airport (STL) to La Crosse hourly. Alternatively, you can take a train from St. Louis Airport (STL) to La Crosse via CIVIC CENTER station, St. Louis Gateway Station, and Chicago Union Station in around 13h 7m.

Airlines
Delta
Website
delta.com
Flights from St. Louis to La Crosse via Minneapolis
Ave. Duration
4h 13m
When
Every day
Estimated price
$190 - $1,000
Flights from St. Louis to La Crosse via Detroit
Ave. Duration
4h 20m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$220 - $1,100
Flights from St. Louis to La Crosse via Covington, Minneapolis
Ave. Duration
6h 42m
When
Monday to Friday
Estimated price
$230 - $1,100
Flights from St. Louis to La Crosse via Detroit, Minneapolis
Ave. Duration
7h 23m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$240 - $1,100
Flights from St. Louis to La Crosse via Atlanta, Minneapolis
Ave. Duration
8h 17m
When
Every day
Estimated price
$270 - $1,200
American Airlines
Website
aa.com
Flights from St. Louis to La Crosse via Chicago O'Hare
Ave. Duration
4h 56m
When
Every day
Estimated price
$200 - $1,000
Flights from St. Louis to La Crosse via Charlotte, Chicago O'Hare
Ave. Duration
7h 43m
When
Every day
Estimated price
$280 - $1,200
Flights from St. Louis to La Crosse via Reagan Washington, Chicago O'Hare
Ave. Duration
8h 23m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$290 - $1,200
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from St. Louis Gateway Station to Chicago Union Station
Ave. Duration
5h 40m
Frequency
5 times a day
Estimated price
$40 - $60
Website
amtrak.com
Coach Seat
$40 - $60
Premium
$210 - $300
Flexi Coach Seat
$75 - $110
Business Seat
$75 - $110
Train from Chicago Union Station to La Crosse Amtrak Station
Ave. Duration
4h 56m
Frequency
3 times a day
Estimated price
$40 - $60
Website
amtrak.com
Coach Seat
$40 - $60
Premium
$210 - $300
Flexi Coach Seat
$75 - $110
Business Seat
$75 - $110
Bus operators
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from St. Louis to Chicago, IL
Ave. Duration
5h 45m
Frequency
Twice daily
Estimated price
$29 - $40
Book at
megabus.com
Bus from Chicago to Madison - Langdon & N Park
Ave. Duration
3h 20m
Frequency
4 times a day
Estimated price
$17 - $28
Book at
megabus.com
Badger Bus
Website
badgerbus.com
Bus from Madison, WI - Chazen UW Madison to La Crosse, WI - UW La Crosse - Sanford Hall
Ave. Duration
2h 45m
Frequency
Once a week
Estimated price
$23 - $35
Schedules at
badgerbus.com
Book at
badgerbus.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from St Louis, Mo to Chicago, Il
Ave. Duration
6h
Frequency
Every 4 hours
Estimated price
$35 - $50
Website
greyhound.com
Economy
$35 - $50
Flexible
$60 - $90
Bus from Chicago, Il to Milwaukee, Wi
Ave. Duration
2h 20m
Frequency
Every 4 hours
Estimated price
$15 - $23
Website
greyhound.com
Economy
$15 - $23
Flexible
$35 - $50
Jefferson Lines
Phone
800-451-5333
Email
info@jeffersonlines.com
Website
jeffersonlines.com
Bus from Milwaukee to La Crosse
Ave. Duration
4h 10m
Frequency
Once daily
Estimated price
$40 - $65
Book at
jeffersonlines.com

Want to know more about travelling around United States

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More Questions & Answers

There is no direct flight from St. Louis Airport to La Crosse Airport. The quickest flight takes 4h 9m and has one stopover.

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St. Louis Airport (STL) to La Crosse bus services, operated by Jefferson Lines, arrive at La Crosse station.

More details

St. Louis Airport (STL) to La Crosse train services, operated by Amtrak, arrive at La Crosse Amtrak Station.

More details

Yes, the driving distance between St. Louis Airport (STL) to La Crosse is 429 miles. It takes approximately 8h 14m to drive from St. Louis Airport (STL) to La Crosse.

Get driving directions

American Airlines and Delta offer flights from St. Louis Airport to La Crosse Airport.

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There are 42+ hotels available in La Crosse. Prices start at $59 USD per night.

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