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How to get fromSt. Catharines to Chicago Loopby bus, plane, train (Amtrak), bus (Greyhound), car, train, shuttle, subway or bus (Flixbus)

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There are 10 ways to get from St. Catharines to Chicago Loop by bus, plane, train (Amtrak), bus (Greyhound), car, train, shuttle, subway, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Toronto Pearson International Airport, fly to Chicago O'Hare International Airport

    best
    1. Take the bus from St. Catharines, ON to Toronto Airportbus bus
    2. Fly from Toronto Pearson International Airport (YYZ) to Chicago O'Hare International Airport (ORD)plane plane YYZ - ORD
    6h 9m
    $202–479

  2. Bus via Detroit

    cheapest
    1. Take the bus from St. Catharines, ON - Bus Terminal to Toronto Union Stationbus bus
    2. Take the bus from Toronto to Detroit Bus Stationbus bus
    3. Take the bus from Detroit Bus Station to Chicagobus bus
    18h 5m
    $84–195

  3. Train

    1. Take the train from St. Catharines to Buffalotrain train VIA Rail
    2. Take the train from Buffalo Depew Station to Chicago Union Stationtrain train Lake Shore Limited
    14h 1m
    $155–408

  4. Bus (Greyhound)

    1. Take the bus from Buffalo to Cleveland Bus Stationbus bus Greyhound US0171 / ...
    2. Take the bus from Cleveland Bus Station to Chicago Bus Stationbus bus Greyhound US0164
    15h 59m
    $103–224

  5. Drive 509.3 mi

    1. Drive from St. Catharines to Chicago Loopcar car 509.3 mi
    8h 31m
    $117–169

  6. Bus to Toronto Island Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from St. Catharines, ON - Bus Terminal to Toronto Union Stationbus bus
    2. Fly from Toronto Island Airport (YTZ) to Chicago O'Hare International Airport (ORD)plane plane YTZ - ORD
    6h 27m
    $219–660

  7. Train to Rochester, fly to Chicago Midway International Airport

    1. Take the train from St. Catharines to Rochestertrain train
    2. Fly from Rochester (ROC) to Chicago Midway International Airport (MDW)plane plane ROC - MDW
    7h 11m
    $134–663

  8. Bus to Toronto Island Airport, fly to Chicago Midway International Airport

    1. Take the bus from St. Catharines, ON - Bus Terminal to Toronto Union Stationbus bus
    2. Fly from Toronto Island Airport (YTZ) to Chicago Midway International Airport (MDW)plane plane YTZ - MDW
    6h 23m
    $109–610

  9. Line 12 bus, shuttle, bus to Buffalo Niagara International Airport, fly to Chicago Midway International Airport, subway

    1. Take the bus from St. Catharines Fairview Mall to Niagara Falls Bus Terminalbus bus
    2. Take a shuttle bus from Whirlpool State Park, NY to Niagara Falls USA Official Visitor Centershuttle bus
    3. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    4. Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)plane plane BUF - MDW
    5. Take the subway from Midway to Washington/Wellssubway subway
    6h 48m
    $123–721

  10. Bus to Buffalo Niagara International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus bus
    2. Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)plane plane BUF - ORD
    7h 3m
    $88–481

St. Catharines to Chicago Loop by train

Calendar7Weekly Trains
Duration14h 1mAverage Duration
Ticket$155Cheapest Price
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Questions & Answers

What companies run services between St. Catharines, ON, Canada and Chicago Loop, IL, USA?

You can take a train from St. Catharines to Chicago Union Station via Buffalo Depew Station in around 14h 1m. Alternatively, you can take a bus from St. Catharines Fairview Mall to Washington & Lasalle via Niagara Falls, Buffalo, Cleveland Bus Station, Chicago Bus Station, and Jefferson & Harrison in around 15h 59m.

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