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How to get fromSt. Catharines to Chicago Loopby bus, plane, train (Amtrak), bus (Greyhound), car or bus (Flixbus)

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There are 10 ways to get from St. Catharines to Chicago Loop by bus, plane, train (Amtrak), bus (Greyhound), car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus to Toronto Pearson International Airport, fly to Chicago O'Hare International Airport

    best
    1. Take the bus from St. Catharines, ON to Toronto Airportbus
    2. Fly from Toronto Pearson International Airport (YYZ) to Chicago O'Hare International Airport (ORD)planeYYZ - ORD
    6h 6m
    $198–799

  2. Bus

    cheapest
    1. Take the bus from Buffalo to Cleveland Bus StationbusGreyhound US0170
    2. Take the bus from Cleveland Bus Station to Chicago Bus StationbusGreyhound US0164
    16h 9m
    $73–163

  3. Train

    1. Take the train from St. Catharines to BuffalotrainVIA Rail
    2. Take the train from Buffalo Depew Station to Chicago Union StationtrainLake Shore Limited
    14h 1m
    $95–266

  4. Drive 509.3 mi

    1. Drive from St. Catharines to Chicago Loopcar509.3 mi
    8h 25m
    $117–169

  5. Bus to Buffalo Niagara International Airport, fly to Chicago Midway International Airport

    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus
    2. Fly from Buffalo Niagara International Airport (BUF) to Chicago Midway International Airport (MDW)planeBUF - MDW
    6h 59m
    $115–698

  6. Bus to Buffalo Niagara International Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from Niagara Falls USA to Buffalo Niagara International Airportbus
    2. Fly from Buffalo Niagara International Airport (BUF) to Chicago O'Hare International Airport (ORD)planeBUF - ORD
    7h 13m
    $85–528

  7. Bus to Toronto Island Airport, fly to Chicago Midway International Airport

    1. Take the bus from St. Catharines, ON - Bus Terminal to Toronto Union Stationbus
    2. Fly from Toronto Island Airport (YTZ) to Chicago Midway International Airport (MDW)planeYTZ - MDW
    6h 42m
    $122–572

  8. Bus to Toronto Island Airport, fly to Chicago O'Hare International Airport

    1. Take the bus from St. Catharines, ON - Bus Terminal to Toronto Union Stationbus
    2. Fly from Toronto Island Airport (YTZ) to Chicago O'Hare International Airport (ORD)planeYTZ - ORD
    6h 46m
    $202–502

  9. Bus to Rochester, fly to Chicago Midway International Airport

    1. Take the bus from Niagara Falls, NY to Rochester, NYbus
    2. Fly from Rochester (ROC) to Chicago Midway International Airport (MDW)planeROC - MDW
    8h 9m
    $114–623

  10. Bus via Detroit

    1. Take the bus from St. Catharines Fairview Mall to Dundas St. @ Hwy. 407 Park & Ridebus12
    2. Take the bus from Mississauga to Detroit Bus Stationbus
    3. Take the bus from Detroit Bus Station to Chicagobus
    17h 55m
    $91–182

St. Catharines to Chicago Loop by train

Calendar7Weekly Trains
Duration14h 1mAverage Duration
Ticket$95Cheapest Price
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Questions & Answers

What companies run services between St. Catharines, ON, Canada and Chicago Loop, IL, USA?

You can take a train from St. Catharines to Chicago Union Station via Buffalo Depew Station in around 14h 1m. Alternatively, you can take a bus from St. Catharines Fairview Mall to Washington & Lasalle via Niagara Falls, Buffalo, Cleveland Bus Station, Chicago Bus Station, and Jefferson & Harrison in around 16h 9m.

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