There are 6 ways to get from Springfield to Cairo by bus, taxi, car, plane, or train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, taxi via St. Louis
best- Take the bus from Springfield SMTD Transfer Center to St Louis Bus Station
- Take the bus from St Louis Bus Station to Cape Girardeau
- Take the taxi from Cape Girardeau to Cairo
5h 42m$120–150Drive 222.9 mi
cheapest- Drive from Springfield to Cairo222.9 mi
4h 25m$41–59Taxi to Decatur Airport, fly, taxi
- Take the taxi from Springfield to Decatur Airport (DEC)
- Fly from Decatur Airport (DEC) to Barkley Regional Airport (PAH)DEC - PAH
- Take the taxi from Barkley Regional Airport (PAH) to Cairo
5h 10m$272–768Train, bus, taxi
- Take the train from Springfield to St. Louis
- Take the bus from St Louis Bus Station to Cape Girardeau
- Take the taxi from Cape Girardeau to Cairo
5h 45m$120–178Bus, taxi (Flixbus)
- Take the bus from Springfield SMTD Transfer Center to Paducah Bus StationFlixBus N2521
- Take the taxi from Paducah Bus Station to Cairo
6h 20m$117–199Fly from Abraham Lincoln Capital Airport, taxi
- Fly from Abraham Lincoln Capital Airport (SPI) to Barkley Regional Airport (PAH)SPI - PAH
- Take the taxi from Barkley Regional Airport (PAH) to Cairo
8h 15m$169–647
Decatur Airport (DEC) to Barkley Regional Airport (PAH) flights
Questions & Answers
The cheapest way to get from Springfield to Cairo is to drive which costs $40 - $60 and takes 4h 25m.
The fastest way to get from Springfield to Cairo is to drive which takes 4h 25m and costs $40 - $60.
The distance between Springfield and Cairo is 248 miles. The road distance is 224.2 miles.
The best way to get from Springfield to Cairo without a car is to bus and taxi via St. Louis which takes 5h 42m and costs $120 - $150.
It takes approximately 5h 42m to get from Springfield to Cairo, including transfers.
Yes, the driving distance between Springfield to Cairo is 224 miles. It takes approximately 4h 25m to drive from Springfield to Cairo.
There are three+ hotels available in Cairo.
What companies run services between Springfield, IL, USA and Cairo, IL, USA?
There is no direct connection from Springfield to Cairo. However, you can take the bus to St Louis Bus Station, take the bus to Cape Girardeau, then take the taxi to Cairo. Alternatively, you can drive from Springfield to Cairo in around 4h 25m.
- Website
- united.com
Flights from Decatur Airport to Barkley Regional Airport via Chicago O'Hare
- Ave. Duration
- 3h 43m
- When
- Every day
- Estimated price
- $90–550
Flights from Abraham Lincoln Capital Airport to Barkley Regional Airport via Chicago O'Hare
- Ave. Duration
- 7h 27m
- When
- Every day
- Estimated price
- $90–550
- Website
- contouraviation.com
Flights from Abraham Lincoln Capital Airport to Barkley Regional Airport via Chicago O'Hare, Charlotte
- Ave. Duration
- 13h 15m
- When
- Every day
- Estimated price
- $150–750
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Springfield to St. Louis
- Ave. Duration
- 1h 48m
- Frequency
- 5 times a day
- Estimated price
- $18–55
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Springfield SMTD Transfer Center to St Louis Bus Station
- Ave. Duration
- 1h 45m
- Frequency
- 3 times a day
- Estimated price
- $17–28
- Schedules at
- flixbus.com
Bus from Springfield SMTD Transfer Center to Paducah Bus Station
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $30–90
- Schedules at
- flixbus.com
- Adult
- $30–90
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from St Louis Bus Station to Cape Girardeau
- Ave. Duration
- 2h 5m
- Frequency
- Once daily
- Estimated price
- $22–28
- Website
- https://www.greyhound.com/
- Ave. Duration
- 47 min
- Estimated price
- $65–140
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
Howard's Taxi Full Throttle
- Phone
- +1-573-270-9932
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