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There are 5 ways to get from South Dakota to Des Moines by bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  9h 2m

  1. Take the bus from Sioux Falls, SD to Omaha, NE 501
  2. Take the bus from Omaha, NE to Des Moines, IA 1202

$72 - $104

4 alternative options

Bus via Des Moines, IA  •  9h 18m

  1. Take the bus from Sioux Falls, SD to Omaha, NE 501
  2. Take the bus from Omaha, NE to Des Moines, IA 1402

$72 - $108

Drive  •  4h 29m

  1. Drive from Sioux Falls to Des Moines 286.8 miles

$28 - $45

Fly from Sioux Falls  •  7h 12m

  1. Fly from Sioux Falls (FSD) to Des Moines (DSM) FSD - DSM

$334 - $1,806

Fly from Pierre  •  5h 28m

  1. Fly from Pierre (PIR) to Des Moines (DSM) PIR - DSM

$134 - $617

Questions & Answers

The cheapest way to get from South Dakota to Des Moines is to drive which costs $28 - $45 and takes 4h 29m.

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The quickest way to get from South Dakota to Des Moines is to drive which costs $28 - $45 and takes 4h 29m.

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No, there is no direct bus from South Dakota to Des Moines. However, there are services departing from 10th/Jessica NW corner and arriving at Des Moines, IA via The Bus Stop, Sioux Falls, SD and Omaha, NE. The journey, including transfers, takes approximately 9h 2m.

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The distance between South Dakota and Des Moines is 402 miles. The road distance is 286.8 miles.

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The best way to get from South Dakota to Des Moines without a car is to bus which takes 9h 2m and costs $70 - $110.

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It takes approximately 9h 2m to get from South Dakota to Des Moines, including transfers.

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South Dakota to Des Moines bus services, operated by Jefferson Lines, depart from Sioux Falls, SD station.

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The best way to get from South Dakota to Des Moines is to bus which takes 9h 2m and costs $70 - $110. Alternatively, you can fly, which costs $330 - $1,900 and takes 7h 12m.

Mode details

There is no direct flight from Sioux Falls Airport to Des Moines Airport. The quickest flight takes 3h 29m and has one stopover.

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South Dakota to Des Moines bus services, operated by Burlington Trailways, arrive at Des Moines, IA station.

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Map of how to get from South Dakota to Des Moines.
Launch map view
  • Distance: 401.9 miles
  • Duration: 9h 2m

What companies run services between South Dakota, USA and Des Moines, IA, USA?

You can take a bus from Sioux Falls to Des Moines via The Bus Stop, Maple/Career NE corner, Sioux Falls, SD, and Omaha, NE in around 9h 2m. Alternatively, Delta, American Airlines and United Airlines fly from Sioux Falls to Des Moines hourly.

Airlines
United Airlines
Website
united.com
Flights from Sioux Falls to Des Moines via Chicago O'Hare
Ave. Duration
5h 19m
When
Every day
Estimated price
$430 - $2,000
Flights from Sioux Falls to Des Moines via Denver
Ave. Duration
6h 40m
When
Every day
Estimated price
$470 - $2,100
Flights from Pierre to Des Moines via Denver
Ave. Duration
4h 34m
When
Every day
Estimated price
$120 - $600
American Airlines
Website
aa.com
Flights from Sioux Falls to Des Moines via Chicago O'Hare
Ave. Duration
5h 22m
When
Every day
Estimated price
$410 - $1,900
Flights from Sioux Falls to Des Moines via Dallas/Ft.Worth
Ave. Duration
5h 22m
When
Every day
Estimated price
$500 - $2,100
Flights from Pierre to Des Moines via Denver, Dallas/Ft.Worth
Ave. Duration
7h 54m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$150 - $600
Flights from Pierre to Des Moines via Denver, Chicago O'Hare
Ave. Duration
7h 57m
When
Every day
Estimated price
$140 - $600
Delta
Website
delta.com
Flights from Sioux Falls to Des Moines via Minneapolis
Ave. Duration
4h 18m
When
Every day
Estimated price
$330 - $1,800
Bus operators
Jefferson Lines
Phone
800-451-5333
Email
info@jeffersonlines.com
Website
jeffersonlines.com
Bus from Sioux Falls, SD to Omaha, NE
Ave. Duration
3h 35m
Frequency
Once daily
Estimated price
$40 - $60
Book at
jeffersonlines.com

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More Questions & Answers

Yes, the driving distance between South Dakota to Des Moines is 287 miles. It takes approximately 4h 29m to drive from South Dakota to Des Moines.

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American Airlines, Delta and United Airlines offer flights from Sioux Falls Airport to Des Moines Airport.

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There are 109+ hotels available in Des Moines. Prices start at $69 USD per night.

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The best way to get from South Dakota to Pierre Airport is to taxi which takes 5m and costs $13 - $16.

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