There are 9 ways to get from South Carolina to San Antonio by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Charlotte to San Antonio  •  4 h 21 min

  1. Fly from Charlotte (CLT) to San Antonio (SAT) CLT - SAT

$260 - $745

Cheapest option

Bus via New Orleans  •  27 h 31 min

  1. Take the bus from Florence, SC to Atlanta, Ga
  2. Take the bus from Marta Civic Center Station - Nb to New Orleans
  3. Take the bus from New Orleans to San Antonio

$126 - $183

7 alternative options

Fly Greenville/Spartanburg to San Antonio  •  5 h 23 min

  1. Fly from Greenville/Spartanburg (GSP) to San Antonio (SAT) GSP - SAT

$208 - $794

Fly Charlotte to Austin, bus  •  6 h 3 min

  1. Fly from Charlotte (CLT) to Austin (AUS) CLT - AUS
  2. Take the bus from Austin, Tx to San Antonio, Tx

$234 - $686

Fly Greenville/Spartanburg to Austin, bus  •  7 h 11 min

  1. Fly from Greenville/Spartanburg (GSP) to Austin (AUS) GSP - AUS
  2. Take the bus from Austin, Tx to San Antonio, Tx

$222 - $935

Fly Charleston to San Antonio  •  7 h 43 min

  1. Fly from Charleston (CHS) to San Antonio (SAT) CHS - SAT

$186 - $858

Bus Greyhound USA  •  28 h 45 min

  1. Take the bus from Florence, Sc to Savannah, Ga
  2. Take the bus from Savannah, Ga to Atlanta, Ga
  3. Take the bus from Atlanta, Ga to Houston, Tx
  4. Take the bus from Houston, Tx to San Antonio, Tx

$151 - $383

Bus, train  •  42 h 8 min

  1. Take the bus from Florence, Sc to Raleigh, Nc
  2. Take the bus from Raleigh, Nc to Greensboro, Nc
  3. Take the train from Greensboro Galyon Transportation Center to New Orleans Union Passenger Terminal
  4. Take the train from New Orleans Union Passenger Terminal to San Antonio Amtrak

$229 - $662

Drive  •  20 h 40 min

  1. Drive from Florence to San Antonio 1279.5 miles

$120 - $190

Questions & Answers

No, there is no direct bus from South Carolina to San Antonio. However, there are services departing from Florence, Sc and arriving at San Antonio, Tx via Savannah, Ga, Atlanta, Ga and Houston, Tx. The journey, including transfers, takes approximately 28 h 45 min.

More details

The distance between South Carolina and San Antonio is 1108 miles. The road distance is 1279.5 miles.

Get driving directions

The best way to get from South Carolina to San Antonio without a car is to bus which takes 27 h 31 min and costs .

More details

It takes approximately 4 h 21 min to get from South Carolina to San Antonio, including transfers.

More details

South Carolina to San Antonio bus services, operated by Greyhound USA, depart from Florence, Sc station.

More details

The best way to get from South Carolina to San Antonio is to fly which takes 4 h 21 min and costs . Alternatively, you can bus, which costs and takes 27 h 31 min.

Mode details

The quickest flight from Charlotte Airport to San Antonio Airport is the direct flight which takes 2 h 50 min.

Search flights

South Carolina to San Antonio bus services, operated by Greyhound USA, arrive at San Antonio, Tx station.

More details

San Antonio is 1 h behind South Carolina. It is currently 3:14 PM in South Carolina and 2:14 PM in San Antonio.

Yes, the driving distance between South Carolina to San Antonio is 1279 miles. It takes approximately 20 h 40 min to drive from South Carolina to San Antonio.

Get driving directions

Map of how to get from South Carolina to San Antonio.
Launch map view
  • Distance: 1108 miles
  • Duration: 4 h 21 min

What companies run services between South Carolina, USA and San Antonio, TX, USA?

American Airlines, Southwest Airlines and two other airlines fly from Rock Hill to San Antonio hourly. Alternatively, you can take a bus from Florence to San Antonio via Atlanta, Ga, Five Points Station, Civic Center Station, Marta Civic Center Station - Nb, and New Orleans in around 27 h 31 min.

Airlines
American Airlines
Website
aa.com
Flights from Charlotte to San Antonio
Ave. Duration
2 h 55 min
When
Every day
Estimated price
$360 - $1,300
Flights from Charlotte to San Antonio via Dallas/Ft.Worth
Ave. Duration
4 h 53 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$360 - $1,300
Flights from Greenville/Spartanburg to San Antonio via Charlotte
Ave. Duration
5 h 22 min
When
Every day
Estimated price
$330 - $1,500
Flights from Greenville/Spartanburg to San Antonio via Dallas/Ft.Worth
Ave. Duration
5 h 30 min
When
Every day
Estimated price
$330 - $1,500
Flights from Greenville/Spartanburg to San Antonio via Chicago O'Hare
Ave. Duration
5 h 51 min
When
Monday to Friday
Estimated price
$330 - $1,500
Flights from Charlotte to Austin
Ave. Duration
2 h 50 min
When
Every day
Estimated price
$290 - $750
Flights from Charlotte to Austin via Dallas/Ft.Worth
Ave. Duration
4 h 54 min
When
Monday, Thursday, Friday and Sunday
Estimated price
$290 - $750
Flights from Greenville/Spartanburg to Austin via Charlotte
Ave. Duration
5 h 18 min
When
Every day
Estimated price
$190 - $850
Flights from Greenville/Spartanburg to Austin via Dallas/Ft.Worth
Ave. Duration
5 h 21 min
When
Every day
Estimated price
$190 - $850
Flights from Greenville/Spartanburg to Austin via Chicago O'Hare
Ave. Duration
5 h 54 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$220 - $900
Flights from Charleston to San Antonio via Charlotte
Ave. Duration
5 h 9 min
When
Every day
Estimated price
$200 - $850
Flights from Charleston to San Antonio via Dallas/Ft.Worth
Ave. Duration
5 h 42 min
When
Every day
Estimated price
$200 - $850
Delta
Website
delta.com
Flights from Charlotte to San Antonio via Atlanta
Ave. Duration
4 h 45 min
When
Every day
Estimated price
$350 - $1,400
Flights from Greenville/Spartanburg to San Antonio via Atlanta
Ave. Duration
4 h 50 min
When
Every day
Estimated price
$330 - $1,500
Flights from Greenville/Spartanburg to San Antonio via Detroit
Ave. Duration
6 h 39 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$330 - $1,500
Flights from Charlotte to Austin via Atlanta
Ave. Duration
4 h 36 min
When
Monday to Saturday
Estimated price
$350 - $950
Flights from Greenville/Spartanburg to Austin via Atlanta
Ave. Duration
4 h 41 min
When
Every day
Estimated price
$170 - $850
Flights from Charleston to San Antonio via Atlanta
Ave. Duration
5 h 15 min
When
Every day
Estimated price
$180 - $850
Southwest Airlines
Website
southwest.com
Flights from Charlotte to San Antonio via Dallas
Ave. Duration
4 h 30 min
When
Monday to Friday
Estimated price
$390 - $1,300
Flights from Charlotte to San Antonio via Nashville
Ave. Duration
4 h 38 min
When
Every day
Estimated price
$390 - $1,300
Flights from Greenville/Spartanburg to San Antonio via Atlanta
Ave. Duration
4 h 44 min
When
Every day
Estimated price
$240 - $950
Flights from Charlotte to Austin via Nashville
Ave. Duration
4 h 33 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$370 - $1,200
Flights from Charlotte to Austin via Dallas
Ave. Duration
4 h 50 min
When
Sunday
Estimated price
$370 - $1,200
Flights from Greenville/Spartanburg to Austin via Atlanta
Ave. Duration
4 h 19 min
When
Every day
Estimated price
$200 - $800
Flights from Charleston to San Antonio via Nashville
Ave. Duration
4 h 45 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$230 - $900
Flights from Charleston to San Antonio via Dallas
Ave. Duration
5 h 7 min
When
Saturday and Sunday
Estimated price
$220 - $850
Flights from Charleston to San Antonio via Houston Hobby Apt
Ave. Duration
5 h 27 min
When
Monday to Saturday
Estimated price
$210 - $850
Flights from Charleston to San Antonio via Chicago Midway
Ave. Duration
5 h 50 min
When
Monday to Friday
Estimated price
$270 - $1,000
United Airlines
Website
united.com
Flights from Charlotte to San Antonio via Houston
Ave. Duration
4 h 49 min
When
Every day
Estimated price
$370 - $1,500
Flights from Greenville/Spartanburg to San Antonio via Houston
Ave. Duration
4 h 42 min
When
Every day
Estimated price
$410 - $1,800
Flights from Greenville/Spartanburg to San Antonio via Washington Dulles
Ave. Duration
5 h 59 min
When
Every day
Estimated price
$410 - $1,800
Flights from Greenville/Spartanburg to San Antonio via Chicago O'Hare
Ave. Duration
6 h 1 min
When
Every day
Estimated price
$410 - $1,800
Flights from Charlotte to Austin via Houston
Ave. Duration
4 h 34 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$310 - $1,000
Flights from Greenville/Spartanburg to Austin via Houston
Ave. Duration
5 h 30 min
When
Every day
Estimated price
$190 - $900
Flights from Greenville/Spartanburg to Austin via Washington Dulles
Ave. Duration
5 h 44 min
When
Every day
Estimated price
$230 - $1,000
Flights from Greenville/Spartanburg to Austin via Chicago O'Hare
Ave. Duration
5 h 55 min
When
Every day
Estimated price
$220 - $1,000
Flights from Charleston to San Antonio via Houston
Ave. Duration
4 h 54 min
When
Every day
Estimated price
$200 - $900
Flights from Charleston to San Antonio via Washington Dulles
Ave. Duration
5 h 54 min
When
Every day
Estimated price
$240 - $1,000
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Greensboro Galyon Transportation Center to New Orleans Union Passenger Terminal
Ave. Duration
20 h 10 min
Frequency
Once daily
Estimated price
$110 - $340
Website
amtrak.com
Coach Seat
$110 - $180
Flexi Coach Seat
$210 - $300
Business Coach Seat
$240 - $340
Room
$470 - $650
Train from New Orleans Union Passenger Terminal to San Antonio Amtrak
Ave. Duration
15 h 5 min
Frequency
3 times a week
Estimated price
$85 - $240
Website
amtrak.com
Coach Seat
$85 - $130
Flexi Coach Seat
$150 - $220
Business Coach Seat
$160 - $240
Room
$350 - $490
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Austin, Tx to San Antonio, Tx
Ave. Duration
1 h 30 min
Frequency
Every 10 minutes
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$25 - $35
Bus from Florence, Sc to Savannah, Ga
Ave. Duration
3 h
Frequency
Every 30 minutes
Estimated price
$22 - $55
Website
greyhound.com
Economy
$22 - $35
Flexible
$40 - $55
Bus from Savannah, Ga to Atlanta, Ga
Ave. Duration
4 h 25 min
Frequency
Every 15 minutes
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $50
Flexible
$55 - $70
Bus from Atlanta, Ga to Houston, Tx
Ave. Duration
17 h 35 min
Frequency
Every 15 minutes
Estimated price
$75 - $200
Website
greyhound.com
Economy
$75 - $130
Flexible
$150 - $200
Bus from Houston, Tx to San Antonio, Tx
Ave. Duration
3 h 15 min
Frequency
Every 30 minutes
Estimated price
$24 - $60
Website
greyhound.com
Economy
$24 - $40
Flexible
$45 - $60
Bus from Florence, Sc to Raleigh, Nc
Ave. Duration
2 h 50 min
Frequency
Hourly
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $35
Flexible
$35 - $50
Bus from Raleigh, Nc to Greensboro, Nc
Ave. Duration
1 h 55 min
Frequency
Every 15 minutes
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$25 - $35
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Marta Civic Center Station - Nb to New Orleans
Ave. Duration
8 h 35 min
Frequency
Twice daily
Estimated price
$40 - $60
Book at
megabus.com
Bus from New Orleans to San Antonio
Ave. Duration
11 h
Frequency
Twice daily
Estimated price
$45 - $65
Book at
megabus.com

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

Delta, United Airlines, American Airlines and Southwest Airlines offer flights from Charlotte Airport to San Antonio Airport.

Search flights

Book your South Carolina to San Antonio bus tickets online with Greyhound, Greyhound and two other operators.

Search and book

There are 409+ hotels available in San Antonio. Prices start at $52 USD per night.

More details

The best way to get from South Carolina to Charlotte Airport is to taxi which takes 35 min and costs .

More details