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There are 8 ways to get from South Carolina to San Antonio by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Greenville/Spartanburg to San Antonio  •  5h 49m

  1. Fly from Greenville/Spartanburg (GSP) to San Antonio (SAT) GSP - SAT

$208 - $794

Cheapest option

Bus via New Orleans  •  27h 41m

  1. Take the bus from Florence, SC to Atlanta, Ga
  2. Take the bus from Marta Civic Center Station - Nb to New Orleans
  3. Take the bus from New Orleans to San Antonio

$126 - $183

6 alternative options

Bus to Charlotte, fly to San Antonio  •  6h 55m

  1. Take the bus from White Street Park and Ride to Johnson & Wales Way & 4th St
  2. Fly from Charlotte (CLT) to San Antonio (SAT) CLT - SAT

$190 - $663

Fly Charleston to San Antonio  •  8h

  1. Fly from Charleston (CHS) to San Antonio (SAT) CHS - SAT

$186 - $858

Fly Greenville/Spartanburg to Austin, bus  •  8h 5m

  1. Fly from Greenville/Spartanburg (GSP) to Austin (AUS) GSP - AUS
  2. Take the bus from Austin, Tx to San Antonio, Tx

$222 - $935

Bus Greyhound USA  •  31h 14m

  1. Take the bus from Florence, Sc to Savannah, Ga
  2. Take the bus from Savannah, Ga to Atlanta, Ga
  3. Take the bus from Atlanta, Ga to Houston, Tx
  4. Take the bus from Houston, Tx to San Antonio, Tx

$151 - $383

Train  •  42h 57m

  1. Take the train from Florence Amtrak Station to Selma-Smithfield Amtrak Station
  2. Take the train from Selma-Smithfield Amtrak Station to Greensboro Amtrak Station
  3. Take the train from Greensboro Amtrak Station to New Orleans Union Passenger Terminal
  4. Take the train from New Orleans Union Passenger Terminal to San Antonio Amtrak Station

$259 - $725

Drive  •  20h 40m

  1. Drive from Florence to San Antonio 1279.5 miles

$120 - $190

Questions & Answers

The cheapest way to get from South Carolina to San Antonio is to bus which costs $120 - $190 and takes 27h 41m.

More details

The quickest way to get from South Carolina to San Antonio is to fly which costs $200 - $800 and takes 5h 49m.

More details

No, there is no direct bus from South Carolina to San Antonio. However, there are services departing from Florence, Sc and arriving at San Antonio, Tx via Savannah, Ga, Atlanta, Ga and Houston, Tx. The journey, including transfers, takes approximately 31h 14m.

More details

No, there is no direct train from South Carolina station to San Antonio station. However, there are services departing from Florence Amtrak Station and arriving at San Antonio Amtrak Station via Selma-Smithfield Amtrak Station, Greensboro Amtrak Station and New Orleans Union Passenger Terminal. The journey, including transfers, takes approximately 42h 57m.

More details

The distance between South Carolina and San Antonio is 1108 miles. The road distance is 1279.5 miles.

Get driving directions

The best way to get from South Carolina to San Antonio without a car is to bus which takes 27h 41m and costs $120 - $190.

More details

It takes approximately 5h 49m to get from South Carolina to San Antonio, including transfers.

More details

South Carolina to San Antonio bus services, operated by Greyhound USA, depart from Florence, Sc station.

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South Carolina to San Antonio train services, operated by Amtrak, arrive at Florence Amtrak Station.

More details

The best way to get from South Carolina to San Antonio is to fly which takes 5h 49m and costs $200 - $800. Alternatively, you can bus, which costs $120 - $190 and takes 27h 41m, you could also train, which costs $250 - $750 and takes 42h 57m.

Mode details

Map of how to get from South Carolina to San Antonio.
Launch map view
  • Distance: 1108 miles
  • Duration: 5h 49m

What companies run services between South Carolina, USA and San Antonio, TX, USA?

Delta, Southwest Airlines and two other airlines fly from Greenville to San Antonio hourly. Alternatively, you can take a bus from Florence to San Antonio via Atlanta, Ga, Five Points Station, Civic Center Station, Marta Civic Center Station - Nb, and New Orleans in around 27h 41m.

Airlines
Delta
Website
delta.com
Flights from Greenville/Spartanburg to San Antonio via Atlanta
Ave. Duration
5h 4m
When
Every day
Estimated price
$330 - $1,500
Flights from Greenville/Spartanburg to San Antonio via Detroit
Ave. Duration
6h 36m
When
Monday to Friday
Estimated price
$330 - $1,500
Flights from Charlotte to San Antonio via Atlanta
Ave. Duration
5h 4m
When
Every day
Estimated price
$350 - $1,400
Flights from Charleston to San Antonio via Atlanta
Ave. Duration
5h 44m
When
Every day
Estimated price
$180 - $850
Flights from Greenville/Spartanburg to Austin via Atlanta
Ave. Duration
5h 22m
When
Every day
Estimated price
$170 - $850
Flights from Greenville/Spartanburg to Austin via Detroit
Ave. Duration
6h 30m
When
Monday to Friday
Estimated price
$210 - $950
American Airlines
Website
aa.com
Flights from Greenville/Spartanburg to San Antonio via Dallas/Ft.Worth
Ave. Duration
6h 44m
When
Every day
Estimated price
$330 - $1,500
Flights from Greenville/Spartanburg to San Antonio via Charlotte
Ave. Duration
6h 35m
When
Every day
Estimated price
$330 - $1,500
Flights from Charlotte to San Antonio
Ave. Duration
3h 9m
When
Every day
Estimated price
$360 - $1,300
Flights from Charlotte to San Antonio via Dallas/Ft.Worth
Ave. Duration
5h 12m
When
Every day
Estimated price
$360 - $1,300
Flights from Charleston to San Antonio via Charlotte
Ave. Duration
6h 2m
When
Every day
Estimated price
$200 - $850
Flights from Charleston to San Antonio via Dallas/Ft.Worth
Ave. Duration
5h 59m
When
Every day
Estimated price
$200 - $850
Flights from Greenville/Spartanburg to Austin via Dallas/Ft.Worth
Ave. Duration
5h 35m
When
Every day
Estimated price
$190 - $850
Flights from Greenville/Spartanburg to Austin via Charlotte
Ave. Duration
6h 23m
When
Every day
Estimated price
$190 - $850
Flights from Greenville/Spartanburg to Austin via Chicago O'Hare
Ave. Duration
6h 5m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$220 - $900
Southwest Airlines
Website
southwest.com
Flights from Greenville/Spartanburg to San Antonio via Atlanta
Ave. Duration
4h 48m
When
Every day
Estimated price
$240 - $950
Flights from Charlotte to San Antonio via Nashville
Ave. Duration
5h 2m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$390 - $1,300
Flights from Charlotte to San Antonio via Dallas
Ave. Duration
5h 15m
When
Monday to Friday
Estimated price
$390 - $1,300
Flights from Charleston to San Antonio via Houston Hobby Apt
Ave. Duration
5h
When
Sunday
Estimated price
$210 - $850
Flights from Charleston to San Antonio via Dallas
Ave. Duration
5h 16m
When
Every day
Estimated price
$220 - $850
Flights from Charleston to San Antonio via Nashville
Ave. Duration
5h 25m
When
Monday to Friday
Estimated price
$230 - $900
Flights from Charleston to San Antonio via Chicago Midway
Ave. Duration
6h 5m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$270 - $1,000
Flights from Greenville/Spartanburg to Austin via Atlanta
Ave. Duration
4h 38m
When
Monday to Saturday
Estimated price
$200 - $800
United Airlines
Website
united.com
Flights from Greenville/Spartanburg to San Antonio via Houston
Ave. Duration
5h 17m
When
Monday to Friday
Estimated price
$410 - $1,800
Flights from Greenville/Spartanburg to San Antonio via Washington Dulles
Ave. Duration
6h 15m
When
Every day
Estimated price
$410 - $1,800
Flights from Greenville/Spartanburg to San Antonio via Chicago O'Hare
Ave. Duration
6h 57m
When
Every day
Estimated price
$410 - $1,800
Flights from Charlotte to San Antonio via Houston
Ave. Duration
5h 5m
When
Every day
Estimated price
$370 - $1,500
Flights from Charleston to San Antonio via Houston
Ave. Duration
5h 18m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$200 - $900
Flights from Charleston to San Antonio via Washington Dulles
Ave. Duration
6h 25m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$240 - $1,000
Flights from Greenville/Spartanburg to Austin via Houston
Ave. Duration
5h
When
Saturday
Estimated price
$190 - $900
Flights from Greenville/Spartanburg to Austin via Washington Dulles
Ave. Duration
6h 8m
When
Every day
Estimated price
$230 - $1,000
Flights from Greenville/Spartanburg to Austin via Chicago O'Hare
Ave. Duration
6h 34m
When
Every day
Estimated price
$220 - $1,000
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Florence Amtrak Station to Selma-Smithfield Amtrak Station
Ave. Duration
2h 13m
Frequency
Once daily
Estimated price
$30 - $75
Website
amtrak.com
Coach Seat
$30 - $50
Flexi Coach Seat
$55 - $85
Business Coach Seat
$50 - $75
Room
$170 - $240
Train from Selma-Smithfield Amtrak Station to Greensboro Amtrak Station
Ave. Duration
2h 29m
Frequency
Once daily
Estimated price
$30 - $70
Website
amtrak.com
Coach Seat
$30 - $45
Flexi Coach Seat
$55 - $80
Business Coach Seat
$45 - $70
Room
$160 - $230
Train from Greensboro Amtrak Station to New Orleans Union Passenger Terminal
Ave. Duration
20h 10m
Frequency
Once daily
Estimated price
$110 - $340
Website
amtrak.com
Coach Seat
$110 - $180
Flexi Coach Seat
$210 - $300
Business Coach Seat
$240 - $340
Room
$470 - $650
Train from New Orleans Union Passenger Terminal to San Antonio Amtrak Station
Ave. Duration
15h 5m
Frequency
3 times a week
Estimated price
$85 - $240
Website
amtrak.com
Coach Seat
$85 - $130
Flexi Coach Seat
$150 - $220
Business Coach Seat
$160 - $240
Room
$350 - $490
Bus operators
Charlotte Area Transit System
Phone
+1 704-336-7433
Email
telltransit@charlottenc.gov
Website
charlottenc.gov
Bus from White Street Park and Ride to Johnson & Wales Way & 4th St
Ave. Duration
1h 1m
Frequency
3 times a day
Estimated price
$3 - $5
Schedules at
charlottenc.gov
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Austin, Tx to San Antonio, Tx
Ave. Duration
1h 30m
Frequency
Hourly
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$25 - $35
Bus from Florence, Sc to Savannah, Ga
Ave. Duration
3h
Frequency
5 times a day
Estimated price
$22 - $55
Website
greyhound.com
Economy
$22 - $35
Flexible
$40 - $55
Bus from Savannah, Ga to Atlanta, Ga
Ave. Duration
4h 25m
Frequency
Every 2 hours
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $50
Flexible
$55 - $70
Bus from Atlanta, Ga to Houston, Tx
Ave. Duration
17h 35m
Frequency
Every 2 hours
Estimated price
$75 - $200
Website
greyhound.com
Economy
$75 - $130
Flexible
$150 - $200
Bus from Houston, Tx to San Antonio, Tx
Ave. Duration
3h 14m
Frequency
4 times a day
Estimated price
$24 - $60
Website
greyhound.com
Economy
$24 - $40
Flexible
$45 - $60
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Marta Civic Center Station - Nb to New Orleans
Ave. Duration
8h 35m
Frequency
Twice daily
Estimated price
$40 - $60
Book at
megabus.com
Bus from New Orleans to San Antonio
Ave. Duration
11h 10m
Frequency
Twice daily
Estimated price
$45 - $65
Book at
megabus.com

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More Questions & Answers

There is no direct flight from Greenville/Spartanburg Airport to San Antonio Airport. The quickest flight takes 4h 34m and has one stopover.

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South Carolina to San Antonio bus services, operated by Greyhound USA, arrive at San Antonio, Tx station.

More details

San Antonio is 1h behind South Carolina. It is currently 3:07 PM in South Carolina and 2:07 PM in San Antonio.

South Carolina to San Antonio train services, operated by Amtrak, arrive at San Antonio Amtrak Station.

More details

Yes, the driving distance between South Carolina to San Antonio is 1279 miles. It takes approximately 20h 40m to drive from South Carolina to San Antonio.

Get driving directions

Southwest Airlines, United Airlines, American Airlines and Delta offer flights from Greenville/Spartanburg Airport to San Antonio Airport.

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Book your South Carolina to San Antonio train tickets online with Rome2rio.

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Book your South Carolina to San Antonio bus tickets online with Greyhound, Greyhound and two other operators.

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There are 428+ hotels available in San Antonio. Prices start at $52 USD per night.

More details

The best way to get from South Carolina to Greenville/Spartanburg Airport is to taxi which takes 18m and costs $35 - $45.

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