Travel from South-Carolina to Missouri

Train, bus or fly from South Carolina to Missouri?

American Airlines, Delta and United Airlines fly from Rock Hill to Springfield every 2 hours. Alternatively, Megabus operates a bus from Columbia to Kansas City 5 times a day. Tickets cost $21 - $35 and the journey takes 3 h 40 min. 4 other operators also service this route.

Travel Guides

Need to know: GreyhoundRome2rio’s guide on the bus operator has all the information you need
Want to know more about US trains?Rome2rio has everything you need to know about travelling with Amtrak

How to get from South Carolina to Missouri

From Rock Hill taxi to Charlotte airport, fly to Springfield airport, then taxi to Springfield. 3 h 10 min $422. From Centre Pointe Dr / Tanger Outlet Blvd line 11 bus to Charleston airport, fly to St. Louis airport, train to North Hanley Transit Center, then line 34 bus to Saint Charles. 4 h 16 min $346. From Greenville taxi to Greenville/Spartanburg airport, fly to Springfield airport, then taxi to Springfield. 4 h 24 min $662. From Rock Hill taxi to Charlotte airport, fly to St. Louis airport, train to North Hanley Transit Center, then line 34 bus to Saint Charles. 3 h 33 min $316. From Greenville taxi to Greenville/Spartanburg airport, fly to St. Louis airport, train to North Hanley Transit Center, then line 34 bus to Saint Charles. 5 h 3 min $366. From Rock Hill taxi to Charlotte airport, fly to Kansas City airport, then line 229 bus to Kansas City. 4 h 28 min $644. From Columbia bus to Civic Center Station, subway to Atlanta, GA, bus to Nashville, TN, bus to St. Louis, MO, then bus to Kansas City, KS. 22 h 44 min $143. From Columbia bus to Civic Center Station, subway to Atlanta, GA, bus to Nashville, TN, bus to St. Louis Gateway Station Amtrak, train to On Grand Across From Crown Ctr Shops Nb Mb, then bus to On Grand At 12Th Northbound. 24 h 9 min $206. From Columbia bus to Garnett Station, subway to Marta Civic Center Station - Nb, Megabus to Little Rock, taxi to Little Rock, AR, then bus to Kansas City, MO. 28 h 33 min $188. From Columbia Amtrak train to Washington Union Station Amtrak, train to Chicago Union Station Amtrak, then train to Kansas City Amtrak. 37 h 28 min $500. From Columbia drive to Kansas City. 16 h 39 min $119.
Close Print Itinerary
  1. Here are 11 options to get from
    South Carolina to Missouri:

    1. Trip:
      1 Fly Charlotte to Springfield
      • One-Way approx: USD $384 - $593
      • Duration: 3 h 10 min
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      • Trip:
        1 Fly Charlotte to Springfield
        • One-Way approx: USD $384 - $593
        • Duration: 3 h 10 min
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    2. Trip:
      2 Fly Charleston to St. Louis
      • One-Way approx: USD $206 - $607
      • Duration: 4 h 16 min
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      • Trip:
        2 Fly Charleston to St. Louis
        • One-Way approx: USD $206 - $607
        • Duration: 4 h 16 min
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    3. Trip:
      3 Fly Greenville/Spartanburg to Springfield
      • One-Way approx: USD $262 - $1,162
      • Duration: 4 h 24 min
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      • Trip:
        3 Fly Greenville/Spartanburg to Springfield
        • One-Way approx: USD $262 - $1,162
        • Duration: 4 h 24 min
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    4. Trip:
      4 Fly Charlotte to St. Louis
      • One-Way approx: USD $222 - $467
      • Duration: 3 h 33 min
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      • Trip:
        4 Fly Charlotte to St. Louis
        • One-Way approx: USD $222 - $467
        • Duration: 3 h 33 min
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    5. Trip:
      5 Fly Greenville/Spartanburg to St. Louis
      • One-Way approx: USD $200 - $456
      • Duration: 5 h 3 min
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      • Trip:
        5 Fly Greenville/Spartanburg to St. Louis
        • One-Way approx: USD $200 - $456
        • Duration: 5 h 3 min
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    6. Trip:
      6 Fly Charlotte to Kansas City
      • One-Way approx: USD $270 - $1,045
      • Duration: 4 h 28 min
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      • Trip:
        6 Fly Charlotte to Kansas City
        • One-Way approx: USD $270 - $1,045
        • Duration: 4 h 28 min
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    7. Trip:
      7 Bus
      • One-Way approx: USD $113 - $265
      • Duration: 22 h 44 min
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      • Trip:
        7 Bus
        • One-Way approx: USD $113 - $265
        • Duration: 22 h 44 min
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    8. Trip:
      8 Bus, train
      • One-Way approx: USD $137 - $327
      • Duration: 24 h 9 min
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      • Trip:
        8 Bus, train
        • One-Way approx: USD $137 - $327
        • Duration: 24 h 9 min
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    9. Trip:
      9 Bus, Megabus
      • One-Way approx: USD $160 - $226
      • Duration: 28 h 33 min
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      • Trip:
        9 Bus, Megabus
        • One-Way approx: USD $160 - $226
        • Duration: 28 h 33 min
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    10. Trip:
      10 Train
      • One-Way approx: USD $242 - $707
      • Duration: 37 h 28 min
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      • Trip:
        10 Train
        • One-Way approx: USD $242 - $707
        • Duration: 37 h 28 min
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    11. Trip:
      11 Drive
      • One-Way approx: USD $95 - $150
      • Duration: 16 h 39 min
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      • Trip:
        11 Drive
        • One-Way approx: USD $95 - $150
        • Duration: 16 h 39 min
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