There are 4 ways to get from South Carolina to Lexington by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  1 h 59 min

  1. Fly from Charlotte (CLT) to Lexington (LEX) CLT - LEX

$318 - $833

Cheapest option

Bus  •  15 h 38 min

  1. Take the bus from Florence, SC to Atlanta, Ga Fayetteville
  2. Take the bus from Atlanta, Ga to Lexington, Ky 1104 / ...

$105 - $198

2 alternative options

Bus via Savannah, Ga  •  17 h 20 min

  1. Take the bus from Florence, Sc to Savannah, Ga
  2. Take the bus from Savannah, Ga to Atlanta, Ga
  3. Take the bus from Atlanta, Ga to Lexington, Ky

$119 - $266

Drive  •  8 h 42 min

  1. Drive from Florence to Lexington 511 miles

$50 - $75

Questions & Answers

The distance between South Carolina and Lexington is 376 miles. The road distance is 511 miles.

Get driving directions

The best way to get from South Carolina to Lexington without a car is to bus which takes 15 h 38 min and costs .

More details

It takes approximately 1 h 59 min to get from South Carolina to Lexington, including transfers.

More details

The best way to get from South Carolina to Lexington is to fly which takes 1 h 59 min and costs . Alternatively, you can bus, which costs and takes 15 h 38 min.

Mode details

The quickest flight from Charlotte Airport to Lexington Airport is the direct flight which takes 1 h 10 min.

Search flights

Yes, the driving distance between South Carolina to Lexington is 511 miles. It takes approximately 8 h 42 min to drive from South Carolina to Lexington.

Get driving directions

American Airlines offers flights from Charlotte Airport to Lexington Airport.

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There are 78+ hotels available in Lexington. Prices start at $67 USD per night.

More details

The best way to get from South Carolina to Charlotte Airport is to taxi which takes 35 min and costs .

More details

Map of how to get from South Carolina to Lexington.
Launch map view
  • Distance: 375.7 miles
  • Duration: 1 h 59 min

What companies run services between South Carolina, USA and Lexington, KY, USA?

American Airlines flies from Rock Hill to Lexington every 4 hours. Alternatively, you can take a bus from Florence to Lexington via Atlanta, Ga and Lexington, Ky in around 15 h 38 min.

Airlines
American Airlines
Website
aa.com
Flights from Charlotte to Lexington
Ave. Duration
1 h 14 min
When
Every day
Estimated price
$320 - $1,400
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Atlanta, Ga to Lexington, Ky
Ave. Duration
9 h 20 min
Frequency
Every 30 minutes
Estimated price
$40 - $110
Website
greyhound.com
Economy
$40 - $70
Flexible
$75 - $110
Bus from Florence, Sc to Savannah, Ga
Ave. Duration
3 h
Frequency
Every 30 minutes
Estimated price
$22 - $55
Website
greyhound.com
Economy
$22 - $35
Flexible
$40 - $55
Bus from Savannah, Ga to Atlanta, Ga
Ave. Duration
4 h 25 min
Frequency
Every 15 minutes
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $50
Flexible
$55 - $70

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