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There are 8 ways to get from South Carolina to Kentucky by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Lexington  •  1 h 59 min

  1. Fly from Charlotte (CLT) to Lexington (LEX) CLT - LEX

$318 - $833

Cheapest option

Bus Greyhound USA  •  15 h 45 min

  1. Take the bus from Florence, SC to Atlanta, Ga Fayetteville
  2. Take the bus from Atlanta, Ga to Louisville, Ky 1196 / ...

$78 - $165

6 alternative options

Fly to Ashland  •  1 h 58 min

  1. Fly from Charlotte (CLT) to Ashland (HTS) CLT - HTS

$243 - $924

Fly to Covington  •  2 h 53 min

  1. Fly from Charlotte (CLT) to Covington (CVG) CLT - CVG

$210 - $255

Fly to Louisville  •  3 h 6 min

  1. Fly from Charlotte (CLT) to Louisville (SDF) CLT - SDF

$249 - $996

Fly to Cincinnati, line 8 bus  •  3 h 18 min

  1. Fly from Charlotte (CLT) to Cincinnati (LUK) CLT - LUK
  2. Take the line 8 bus from Federal Reserve - Out to Scott at Fifth - Out

$140 - $538

Bus Megabus  •  15 h 35 min

  1. Take the bus from Florence, SC to Atlanta, Ga Fayetteville
  2. Take the bus from Marta Civic Center Station - Nb to Louisville, KY

$82 - $116

Drive  •  9 h 56 min

  1. Drive from Florence to Louisville 589.1 miles

$55 - $85

Questions & Answers

The cheapest way to get from South Carolina to Kentucky is to drive which costs $55 - $85 and takes 9 h 56 min.

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The quickest way to get from South Carolina to Kentucky is to fly which costs $240 - $950 and takes 1 h 58 min.

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No, there is no direct bus from South Carolina to Kentucky. However, there are services departing from Florence, SC and arriving at Louisville, Ky via Atlanta, Ga. The journey, including transfers, takes approximately 15 h 45 min.

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The distance between South Carolina and Kentucky is 379 miles. The road distance is 589.1 miles.

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The best way to get from South Carolina to Kentucky without a car is to bus which takes 15 h 35 min and costs $80 - $120.

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It takes approximately 1 h 59 min to get from South Carolina to Kentucky, including transfers.

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South Carolina to Kentucky bus services, operated by South Eastern Stages, depart from Florence, SC station.

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The best way to get from South Carolina to Kentucky is to fly which takes 1 h 59 min and costs $310 - $850. Alternatively, you can bus, which costs $80 - $120 and takes 15 h 35 min.

Mode details

The quickest flight from Charlotte Airport to Lexington Airport is the direct flight which takes 1 h 10 min.

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South Carolina to Kentucky bus services, operated by Greyhound USA, arrive at Louisville, Ky station.

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Map of how to get from South Carolina to Kentucky.
Launch map view
  • Distance: 379.3 miles
  • Duration: 1 h 59 min

What companies run services between South Carolina, USA and Kentucky, USA?

American Airlines flies from Rock Hill to Lexington every 4 hours. Alternatively, you can take a bus from Florence to Louisville via Atlanta, Ga, Five Points Station, Civic Center Station, Marta Civic Center Station - Nb, Louisville, KY, and E Broadway @ S Brook in around 15 h 35 min.

Airlines
American Airlines
Website
aa.com
Flights from Charlotte to Lexington
Ave. Duration
1 h 14 min
When
Every day
Estimated price
$320 - $1,400
Flights from Charlotte to Ashland
Ave. Duration
1 h 10 min
When
Every day
Estimated price
$140 - $800
Flights from Charlotte to Covington
Ave. Duration
1 h 23 min
When
Every day
Estimated price
$140 - $330
Flights from Charlotte to Louisville
Ave. Duration
1 h 29 min
When
Every day
Estimated price
$170 - $900
Delta
Website
delta.com
Flights from Charlotte to Covington
Ave. Duration
1 h 32 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$130 - $310
Flights from Charlotte to Covington via Atlanta
Ave. Duration
3 h 33 min
When
Every day
Estimated price
$130 - $310
Flights from Charlotte to Louisville via Atlanta
Ave. Duration
3 h 40 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$170 - $900
Regional Sky
Website
regionalsky.com
Flights from Charlotte to Cincinnati
Ave. Duration
1 h 9 min
When
Monday to Friday
Estimated price
$210 - $550
Texas Sky
Website
texassky.com
Flights from Charlotte to Cincinnati
Ave. Duration
1 h 12 min
When
Monday
Estimated price
$370 - $650
Bus operators
TANK
Phone
+1 859-331-8265
Website
tankbus.org
Bus from Federal Reserve - Out to Scott at Fifth - Out
Ave. Duration
9 min
Frequency
Every 15 minutes
Estimated price
$1 - $2
Schedules at
tankbus.org
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Marta Civic Center Station - Nb to Louisville, KY
Ave. Duration
8 h 15 min
Frequency
Twice daily
Estimated price
$40 - $55
Book at
megabus.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Atlanta, Ga to Louisville, Ky
Ave. Duration
8 h 55 min
Frequency
5 times a day
Estimated price
$40 - $110
Website
greyhound.com
Economy
$40 - $70
Flexible
$80 - $110

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

Yes, the driving distance between South Carolina to Kentucky is 589 miles. It takes approximately 9 h 56 min to drive from South Carolina to Kentucky.

Get driving directions

American Airlines offers flights from Charlotte Airport to Lexington Airport.

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There are five+ hotels available in Kentucky. Prices start at $100 USD per night.

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The best way to get from South Carolina to Charlotte Airport is to taxi which takes 35 min and costs $75 - $95.

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