There are 12 ways to get from South Carolina to Great Lakes by plane, train, taxi, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Charlotte to Chicago Midway, train  •  5 h 2 min

  1. Fly from Charlotte (CLT) to Chicago Midway (MDW) CLT - MDW
  2. Take the train from Chicago OTC to Great Lakes

$247 - $546

Cheapest option

Bus Megabus, train  •  23 h 31 min

  1. Take the bus from Florence, SC to Atlanta, Ga
  2. Take the bus from Marta Civic Center Station - Nb to Chicago
  3. Take the train from Chicago OTC to Great Lakes

$110 - $155

10 alternative options

Fly Greenville/Spartanburg to Chicago O'Hare, train  •  5 h 4 min

  1. Fly from Greenville/Spartanburg (GSP) to Chicago O'Hare (ORD) GSP - ORD
  2. Take the train from Clybourn to Great Lakes

$184 - $605

Fly Columbia to Chicago O'Hare, train  •  5 h 13 min

  1. Fly from Columbia (CAE) to Chicago O'Hare (ORD) CAE - ORD
  2. Take the train from Clybourn to Great Lakes

$243 - $593

Fly Charlotte to Chicago O'Hare, train  •  5 h 21 min

  1. Fly from Charlotte (CLT) to Chicago O'Hare (ORD) CLT - ORD
  2. Take the train from Clybourn to Great Lakes

$216 - $456

Taxi to Asheville, fly to Chicago O'Hare, train  •  5 h 45 min

  1. Take a taxi from Greenville to Asheville
  2. Fly from Asheville (AVL) to Chicago O'Hare (ORD) AVL - ORD
  3. Take the train from Clybourn to Great Lakes

$287 - $497

Fly Charleston to Chicago Midway, train  •  6 h 52 min

  1. Fly from Charleston (CHS) to Chicago Midway (MDW) CHS - MDW
  2. Take the train from Chicago OTC to Great Lakes

$183 - $619

Fly Charleston to Chicago O'Hare, train  •  7 h 15 min

  1. Fly from Charleston (CHS) to Chicago O'Hare (ORD) CHS - ORD
  2. Take the train from Clybourn to Great Lakes

$152 - $489

Bus Greyhound USA, train  •  26 h 54 min

  1. Take the bus from Florence, Sc to Savannah, Ga
  2. Take the bus from Savannah, Ga to Atlanta, Ga
  3. Take the bus from Atlanta, Ga to Chicago Amtrak, Il
  4. Take the train from Chicago OTC to Great Lakes

$129 - $312

Train  •  28 h 32 min

  1. Take the train from Florence Amtrak to Washington Union Station
  2. Take the train from Washington Union Station to Chicago Union Station
  3. Take the train from Chicago OTC to Great Lakes

$173 - $492

Train via Alexandria Amtrak  •  33 h 58 min

  1. Take the train from Florence Amtrak to Alexandria Amtrak
  2. Take the train from Alexandria Amtrak to Chicago Union Station
  3. Take the train from Chicago OTC to Great Lakes

$192 - $529

Drive  •  15 h 30 min

  1. Drive from Florence to Great Lakes 917.5 miles

$90 - $130

Questions & Answers

No, there is no direct train from South Carolina to Great Lakes. However, there are services departing from Florence Amtrak and arriving at Great Lakes via Washington Union Station and Chicago OTC. The journey, including transfers, takes approximately 28 h 32 min.

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The distance between South Carolina and Great Lakes is 723 miles. The road distance is 917.5 miles.

Get driving directions

The best way to get from South Carolina to Great Lakes without a car is to bus and train which takes 23 h 31 min and costs .

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It takes approximately 5 h 2 min to get from South Carolina to Great Lakes, including transfers.

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South Carolina to Great Lakes train services, operated by Amtrak, depart from Florence Amtrak station.

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The quickest flight from Charlotte Airport to Chicago Midway Airport is the direct flight which takes 1 h 50 min.

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Great Lakes is 1 h behind South Carolina. It is currently 2:52 PM in South Carolina and 1:52 PM in Great Lakes.

South Carolina to Great Lakes train services, operated by Metra, arrive at Great Lakes station.

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Yes, the driving distance between South Carolina to Great Lakes is 918 miles. It takes approximately 15 h 30 min to drive from South Carolina to Great Lakes.

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Delta and Southwest Airlines offer flights from Charlotte Airport to Chicago Midway Airport.

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Map of how to get from South Carolina to Great Lakes.
Launch map view
  • Distance: 722.9 miles
  • Duration: 5 h 2 min

What companies run services between South Carolina, USA and Great Lakes, IL, USA?

You can take a train from Florence to Great Lakes via Washington Union Station, Chicago Union Station, and Chicago OTC in around 28 h 32 min.

Airlines
Delta
Website
delta.com
Flights from Charlotte to Chicago Midway via Detroit
Ave. Duration
4 h 7 min
When
Every day
Estimated price
$210 - $700
Flights from Charlotte to Chicago Midway via Atlanta
Ave. Duration
4 h 29 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$210 - $700
Flights from Greenville/Spartanburg to Chicago O'Hare via Atlanta
Ave. Duration
4 h 11 min
When
Every day
Estimated price
$260 - $1,300
Flights from Greenville/Spartanburg to Chicago O'Hare via Detroit
Ave. Duration
4 h 14 min
When
Saturday
Estimated price
$260 - $1,300
Flights from Columbia to Chicago O'Hare via Atlanta
Ave. Duration
4 h 23 min
When
Every day
Estimated price
$420 - $1,000
Flights from Charlotte to Chicago O'Hare via Covington
Ave. Duration
3 h 50 min
When
Monday to Friday
Estimated price
$210 - $600
Flights from Asheville to Chicago O'Hare via Atlanta
Ave. Duration
4 h 25 min
When
Every day
Estimated price
$310 - $750
Flights from Charleston to Chicago Midway via Atlanta
Ave. Duration
4 h 43 min
When
Every day
Estimated price
$280 - $1,400
Flights from Charleston to Chicago Midway via Detroit
Ave. Duration
4 h 23 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$280 - $1,400
Flights from Charleston to Chicago O'Hare via Detroit
Ave. Duration
4 h 20 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$320 - $1,400
Flights from Charleston to Chicago O'Hare via Atlanta
Ave. Duration
4 h 24 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$320 - $1,400
American Airlines
Website
aa.com
Flights from Greenville/Spartanburg to Chicago O'Hare
Ave. Duration
2 h 9 min
When
Every day
Estimated price
$280 - $800
Flights from Greenville/Spartanburg to Chicago O'Hare via Charlotte
Ave. Duration
4 h 17 min
When
Monday to Saturday
Estimated price
$280 - $800
Flights from Columbia to Chicago O'Hare via Charlotte
Ave. Duration
4 h 24 min
When
Every day
Estimated price
$400 - $1,100
Flights from Charlotte to Chicago O'Hare
Ave. Duration
2 h 13 min
When
Every day
Estimated price
$200 - $600
Flights from Charlotte to Chicago O'Hare via Fort Wayne
Ave. Duration
3 h 29 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$200 - $600
Flights from Charlotte to Chicago O'Hare via Covington
Ave. Duration
3 h 44 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$200 - $600
Flights from Charlotte to Chicago O'Hare via Indianapolis
Ave. Duration
3 h 49 min
When
Every day
Estimated price
$200 - $600
Flights from Charlotte to Chicago O'Hare via Louisville
Ave. Duration
3 h 53 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$200 - $600
Flights from Charlotte to Chicago O'Hare via Wilmington
Ave. Duration
3 h 59 min
When
Every day
Estimated price
$200 - $600
Flights from Asheville to Chicago O'Hare via Charlotte
Ave. Duration
4 h 25 min
When
Every day
Estimated price
$290 - $700
Flights from Charleston to Chicago O'Hare
Ave. Duration
2 h 40 min
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$290 - $1,200
Flights from Charleston to Chicago O'Hare via Charlotte
Ave. Duration
4 h 28 min
When
Every day
Estimated price
$290 - $1,200
United Airlines
Website
united.com
Flights from Greenville/Spartanburg to Chicago O'Hare
Ave. Duration
2 h 4 min
When
Every day
Estimated price
$280 - $1,100
Flights from Greenville/Spartanburg to Chicago O'Hare via Washington Dulles
Ave. Duration
4 h 12 min
When
Monday to Friday
Estimated price
$280 - $1,100
Flights from Columbia to Chicago O'Hare
Ave. Duration
2 h 15 min
When
Every day
Estimated price
$320 - $900
Flights from Columbia to Chicago O'Hare via Washington Dulles
Ave. Duration
4 h 15 min
When
Every day
Estimated price
$320 - $900
Flights from Charlotte to Chicago O'Hare
Ave. Duration
2 h 6 min
When
Every day
Estimated price
$180 - $550
Flights from Asheville to Chicago O'Hare
Ave. Duration
2 h 1 min
When
Every day
Estimated price
$290 - $700
Flights from Charleston to Chicago O'Hare
Ave. Duration
2 h 29 min
When
Every day
Estimated price
$300 - $1,100
Flights from Charleston to Chicago O'Hare via Washington Dulles
Ave. Duration
4 h 14 min
When
Every day
Estimated price
$300 - $1,100
Southwest Airlines
Website
southwest.com
Flights from Charlotte to Chicago Midway
Ave. Duration
1 h 52 min
When
Every day
Estimated price
$310 - $800
Flights from Charlotte to Chicago Midway via Nashville
Ave. Duration
4 h
When
Monday to Friday
Estimated price
$310 - $800
Flights from Charlotte to Chicago Midway via Baltimore
Ave. Duration
4 h 35 min
When
Saturday
Estimated price
$310 - $800
Flights from Charleston to Chicago Midway
Ave. Duration
2 h 7 min
When
Every day
Estimated price
$350 - $1,600
Flights from Charleston to Chicago Midway via Nashville
Ave. Duration
4 h
When
Saturday
Estimated price
$350 - $1,600
Flights from Charleston to Chicago Midway via Baltimore
Ave. Duration
4 h 45 min
When
Monday to Friday
Estimated price
$350 - $1,600
Frontier Airlines
Website
flyfrontier.com
Flights from Charleston to Chicago O'Hare
Ave. Duration
2 h 21 min
When
Monday and Friday
Estimated price
$70 - $340
Train operators
Metra
Phone
+1 312-322-6777
Website
metrarail.com
Train from Chicago OTC to Great Lakes
Ave. Duration
1 h 5 min
Frequency
Hourly
Estimated price
$7 - $9
Schedules at
metrarail.com
Train from Clybourn to Great Lakes
Ave. Duration
57 min
Frequency
Hourly
Estimated price
$2 - $4
Schedules at
metrarail.com
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Florence Amtrak to Washington Union Station
Ave. Duration
8 h 3 min
Frequency
Twice daily
Estimated price
$65 - $180
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$110 - $170
Business Coach Seat
$120 - $180
Room
$280 - $400
Train from Washington Union Station to Chicago Union Station
Ave. Duration
17 h 40 min
Frequency
Once daily
Estimated price
$100 - $310
Website
amtrak.com
Coach Seat
$100 - $160
Flexi Coach Seat
$190 - $280
Business Coach Seat
$220 - $310
Room
$440 - $600
Train from Florence Amtrak to Alexandria Amtrak
Ave. Duration
7 h 28 min
Frequency
Twice daily
Estimated price
$60 - $170
Website
amtrak.com
Coach Seat
$60 - $95
Flexi Coach Seat
$110 - $170
Business Coach Seat
$120 - $170
Room
$280 - $390
Train from Alexandria Amtrak to Chicago Union Station
Ave. Duration
23 h 41 min
Frequency
4 times a week
Estimated price
$120 - $350
Website
amtrak.com
Coach Seat
$120 - $180
Flexi Coach Seat
$210 - $310
Business Coach Seat
$250 - $350
Room
$490 - $700
Bus operators
Megabus
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Florence, Sc to Savannah, Ga
Ave. Duration
3 h
Frequency
Every 30 minutes
Estimated price
$22 - $55
Website
greyhound.com
Economy
$22 - $35
Flexible
$40 - $55
Bus from Savannah, Ga to Atlanta, Ga
Ave. Duration
4 h 25 min
Frequency
Every 15 minutes
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $50
Flexible
$55 - $70
Bus from Atlanta, Ga to Chicago Amtrak, Il
Ave. Duration
16 h 55 min
Frequency
Hourly
Estimated price
$70 - $180
Website
greyhound.com
Economy
$70 - $120
Flexible
$130 - $180
Other operators
Taxi from Greenville to Asheville
Ave. Duration
59 min
Estimated price
$130 - $170
Atlantis Taxi
Phone
+1 850-628-5670
Website
facebook.com
Corporate Taxi
Phone
+1 864-990-5556
Website
ataxi.co
Yellow Cab Greenville
Phone
+1 864-233-6666
Website
yellowcabgreenville.com

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More Questions & Answers

There are 81+ hotels available in Great Lakes. Prices start at $62 USD per night.

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The best way to get from South Carolina to Charlotte Airport is to taxi which takes 35 min and costs .

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