There are 4 ways to get from South Carolina to Gainesville by plane, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly from Charlotte  •  3 h 10 min

  1. Fly from Charlotte (CLT) to Gainesville (GNV) CLT - GNV

$340 - $1,495

Cheapest option

Train, drive  •  7 h 20 min

  1. Take the train from Florence Amtrak to Jacksonville Amtrak Silver Meteor
  2. Drive from Jacksonville Amtrak to Gainesville

$64 - $160

2 alternative options

Fly from Greenville/Spartanburg  •  4 h 44 min

  1. Fly from Greenville/Spartanburg (GSP) to Gainesville (GNV) GSP - GNV

$278 - $1,344

Drive  •  6 h 22 min

  1. Drive from Florence to Gainesville 379 miles

$35 - $55

Questions & Answers

The distance between South Carolina and Gainesville is 302 miles. The road distance is 379 miles.

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It takes approximately 3 h 10 min to get from South Carolina to Gainesville, including transfers.

More details

The quickest flight from Charlotte Airport to Gainesville Airport is the direct flight which takes 1 h 20 min.

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Yes, the driving distance between South Carolina to Gainesville is 379 miles. It takes approximately 6 h 22 min to drive from South Carolina to Gainesville.

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American Airlines and Delta offer flights from Charlotte Airport to Gainesville Airport.

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There are 49+ hotels available in Gainesville. Prices start at $64 USD per night.

More details

The best way to get from South Carolina to Charlotte Airport is to taxi which takes 35 min and costs .

More details

Map of how to get from South Carolina to Gainesville.
Launch map view
  • Distance: 301.9 miles
  • Duration: 3 h 10 min

What companies run services between South Carolina, USA and Gainesville, FL, USA?

American Airlines and Delta fly from Rock Hill to Gainesville every 4 hours.

Airlines
American Airlines
Website
aa.com
Flights from Charlotte to Gainesville
Ave. Duration
1 h 23 min
When
Every day
Estimated price
$260 - $1,400
Flights from Greenville/Spartanburg to Gainesville via Charlotte
Ave. Duration
4 h 23 min
When
Every day
Estimated price
$260 - $1,300
Flights from Greenville/Spartanburg to Gainesville via Miami
Ave. Duration
4 h 25 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$310 - $1,400
Flights from Greenville/Spartanburg to Gainesville via Reagan Washington, Charlotte
Ave. Duration
6 h 47 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$330 - $1,500
Flights from Greenville/Spartanburg to Gainesville via Philadelphia, Charlotte
Ave. Duration
6 h 40 min
When
Every day
Estimated price
$360 - $1,500
Delta
Website
delta.com
Flights from Charlotte to Gainesville via Atlanta
Ave. Duration
3 h 28 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$260 - $1,400
Flights from Greenville/Spartanburg to Gainesville via Atlanta
Ave. Duration
3 h 44 min
When
Every day
Estimated price
$240 - $1,300
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Florence Amtrak to Jacksonville Amtrak
Ave. Duration
5 h 56 min
Frequency
Once daily
Estimated price
$55 - $150
Website
amtrak.com
Coach Seat
$55 - $85
Flexi Coach Seat
$100 - $150
Business Coach Seat
$100 - $150
Room
$260 - $360

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