There are 7 ways to get from South Bend to Kirksville by train, car, plane or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train  •  7 h 58 min

  1. Take the train from South Bend Amtrak to Chicago Union Station Capitol Limited / ...
  2. Take the train from Chicago Union Station to La Plata Amtrak Southwest Chief

$108 - $238

Cheapest option

Train via Notre Dame  •  9 h 19 min

  1. Take the train from South Bend Airport to Millennium Station Ssl
  2. Take the train from Chicago Union Station to La Plata Amtrak Southwest Chief

$105 - $212

5 alternative options

Drive  •  7 h 56 min

  1. Drive from South Bend to Kirksville 465.9 miles

$45 - $70

Train to Chicago Midway, fly to Kirksville  •  7 h 7 min

  1. Take the train from South Bend Amtrak to Chicago Union Station
  2. Fly from Chicago Midway (MDW) to Kirksville (IRK) MDW - IRK

$200 - $787

Train to Chicago Midway, fly to St. Louis, bus  •  11 h 22 min

  1. Take the train from South Bend Amtrak to Chicago Union Station
  2. Fly from Chicago Midway (MDW) to St. Louis (STL) MDW - STL
  3. Take the bus from St Louis, Mo to Kirksville

$186 - $449

Fly South Bend to Quincy, train  •  11 h 34 min

  1. Fly from South Bend (SBN) to Quincy (UIN) SBN - UIN
  2. Take the train from Quincy Amtrak to Galesburg Amtrak
  3. Take the train from Galesburg Amtrak to La Plata Amtrak

$365 - $1,445

Train to Chicago O'Hare, fly to Burlington, train  •  11 h 10 min

  1. Take the train from South Bend Amtrak to Chicago Union Station
  2. Fly from Chicago O'Hare (ORD) to Burlington (BRL) ORD - BRL
  3. Take the train from Burlington Amtrak to Galesburg Amtrak
  4. Take the train from Galesburg Amtrak to La Plata Amtrak

$176 - $305

Questions & Answers

The distance between South Bend and Kirksville is 348 miles. The road distance is 465.9 miles.

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The best way to get from South Bend to Kirksville without a car is to train which takes 7 h 58 min and costs .

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It takes approximately 7 h 58 min to get from South Bend to Kirksville, including transfers.

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There is no direct flight from Chicago Midway Airport to Kirksville Airport. The quickest flight takes 9 h 5 min and has one stopover.

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Kirksville is 1 h behind South Bend. It is currently 1:25 PM in South Bend and 12:25 PM in Kirksville.

Yes, the driving distance between South Bend to Kirksville is 466 miles. It takes approximately 7 h 56 min to drive from South Bend to Kirksville.

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Delta, Cape Air and Southwest Airlines offer flights from Chicago Midway Airport to Kirksville Airport.

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There are eight+ hotels available in Kirksville. Prices start at $100 USD per night.

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The best way to get from South Bend to South Bend Airport is to bus which takes 20 min and costs .

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Map of how to get from South Bend to Kirksville.
Launch map view
  • Distance: 348.1 miles
  • Duration: 7 h 58 min

What companies run services between South Bend, IN, USA and Kirksville, MO, USA?

You can take a train from South Bend to Kirksville via Chicago Union Station and La Plata Amtrak in around 7 h 58 min.

Airlines
Southwest Airlines
Website
southwest.com
Flights from Chicago Midway to St. Louis
Ave. Duration
1 h 5 min
When
Every day
Estimated price
$160 - $550
Cape Air
Website
capeair.com
Flights from Chicago Midway to Kirksville via St. Louis
Ave. Duration
4 h 6 min
When
Every day
Estimated price
$150 - $700
Flights from Chicago Midway to Kirksville via Detroit, St. Louis
Ave. Duration
6 h 25 min
When
Monday to Friday
Estimated price
$160 - $800
Flights from Chicago Midway to Kirksville via Kansas City, St. Louis
Ave. Duration
6 h 47 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$190 - $800
Flights from Chicago Midway to Kirksville via Nashville, St. Louis
Ave. Duration
6 h 40 min
When
Saturday and Sunday
Estimated price
$190 - $800
Flights from Chicago Midway to Kirksville via Columbus, St. Louis
Ave. Duration
6 h 40 min
When
Sunday
Estimated price
$190 - $800
Flights from Chicago Midway to Kirksville via Atlanta, St. Louis
Ave. Duration
6 h 45 min
When
Sunday
Estimated price
$190 - $900
Flights from Chicago Midway to Kirksville via Omaha, St. Louis
Ave. Duration
7 h 5 min
When
Sunday
Estimated price
$200 - $800
United Airlines
Website
united.com
Flights from South Bend to Quincy via Chicago O'Hare
Ave. Duration
5 h 18 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$230 - $1,200
Flights from South Bend to Quincy via Newark, Chicago O'Hare
Ave. Duration
8 h 57 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$340 - $1,500
Air Choice One
Website
airchoiceone.com
Flights from Chicago O'Hare to Burlington
Ave. Duration
1 h 40 min
When
Every day
Estimated price
$50 - $120
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from South Bend Amtrak to Chicago Union Station
Ave. Duration
1 h 54 min
Frequency
3 times a day
Estimated price
$28 - $60
Website
amtrak.com
Coach Seat
$28 - $45
Flexi Coach Seat
$50 - $75
Business Coach Seat
$40 - $60
Room
$150 - $210
Train from Chicago Union Station to La Plata Amtrak
Ave. Duration
4 h 47 min
Frequency
Once daily
Estimated price
$50 - $140
Website
amtrak.com
Coach Seat
$50 - $80
Flexi Coach Seat
$90 - $140
Business Coach Seat
$95 - $140
Room
$240 - $330
Train from Quincy Amtrak to Galesburg Amtrak
Ave. Duration
1 h 23 min
Frequency
Twice daily
Estimated price
$29 - $65
Website
amtrak.com
Coach Seat
$29 - $45
Flexi Coach Seat
$50 - $75
Business Coach Seat
$45 - $65
Room
$150 - $220
Train from Galesburg Amtrak to La Plata Amtrak
Ave. Duration
2 h 11 min
Frequency
Once daily
Estimated price
$30 - $80
Website
amtrak.com
Coach Seat
$30 - $50
Flexi Coach Seat
$60 - $85
Business Coach Seat
$55 - $80
Room
$170 - $240
Train from Burlington Amtrak to Galesburg Amtrak
Ave. Duration
1 h 5 min
Frequency
Once daily
Estimated price
$23 - $45
Website
amtrak.com
Coach Seat
$23 - $35
Flexi Coach Seat
$40 - $60
Business Coach Seat
$30 - $45
Room
$130 - $190
South Shore Line
Phone
+1 219-926-5744
Website
nictd.com
Train from South Bend Airport to Millennium Station
Ave. Duration
2 h 29 min
Frequency
Every 30 minutes
Estimated price
$12 - $14
Schedules at
nictd.com
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from St Louis, Mo to Kirksville
Ave. Duration
4 h 40 min
Frequency
Every 4 hours
Estimated price
$28 - $70
Website
greyhound.com
Economy
$28 - $45
Flexible
$50 - $70

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