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How to get fromSistine Chapel to Pisaby train (Trenitalia), bus, car, plane or train

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There are 7 ways to get from Sistine Chapel to Pisa by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via Roma Tiburtina (Trenitalia)

    best
    1. Take the train from Roma Tiburtina to Pisa Centraletrain train Fa
    3h 53m
    €31–66
  2. Bus

    cheapest
    1. Take the bus from Roma, Autostazione Tiburtina to Pisabus bus N1508 / ...
    6h 45m
    €14–29
  3. Drive 323.4 km

    1. Drive from Sistine Chapel to Pisacar car 323.4 km
    3h 45m
    €49–71
  4. Fly to Florence Peretola Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Florence Peretola Airport (FLR)plane plane FCO - FLR
    2. Take the train from Firenze S.M.N. to Pisa Centraletrain train
    4h 52m
    €75–215
  5. Train (Trenitalia)

    1. Take the train from Roma S. Pietro to Pisa Centraletrain train 4134 / ...
    3h 57m
    €17–60
  6. Bus via Pisa Pietrasantina Bus Station

    1. Take the bus from Roma, Autostazione Tiburtina to Pisa Pietrasantina Bus Stationbus bus MarinoBus 206
    7h 44m
    €18–47
  7. Fly to Pisa International Airport

    1. Fly from Fiumicino International Airport (FCO) to Pisa International Airport (PSA)plane plane FCO - PSA
    5h 20m
    €59–219

Sistine Chapel to Pisa by foot and train (Trenitalia)

Calendar7Weekly Services
Duration3h 53mAverage Duration
Ticket€31Cheapest Price
See schedules

Questions & Answers

What companies run services between Sistine Chapel, Vatican City and Pisa, Italy?

Trenitalia Frecce operates a train from Roma Tiburtina to Pisa Centrale once daily. Tickets cost €30–65 and the journey takes 2h 13m. Alternatively, FlixBus operates a bus from Roma, Autostazione Tiburtina to Pisa 4 times a day. Tickets cost €12–22 and the journey takes 4h 35m.

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