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How to get fromSistine Chapel to Pisaby train (Trenitalia), bus, car, plane or train

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There are 8 ways to get from Sistine Chapel to Pisa by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Trenitalia)

    best
    1. Take the train from Roma S. Pietro to Pisa Centraletrain train 4134 / ...
    3h 57m
    €20–60

  2. Bus

    cheapest
    1. Take the bus from Roma, Autostazione Tiburtina to Pisabus bus N1508 / ...
    6h 45m
    €14–31

  3. Drive 323.3 km

    1. Drive from Sistine Chapel to Pisacar car 323.3 km
    3h 45m
    €50–72

  4. Fly to Pisa International Airport

    1. Fly from Fiumicino International Airport (FCO) to Pisa International Airport (PSA)plane plane FCO - PSA
    5h 20m
    €59–209

  5. Train via Florence

    1. Take the train from Roma Termini to Florence Santa Maria Novellatrain train 8960 / ...
    2. Take the train from Firenze S.M.N. to Pisa Centraletrain train Re / ...
    4h 3m
    €32–76

  6. Bus via Pisa

    1. Take the bus from Roma, Autostazione Tiburtina to Pisabus bus
    7h 29m
    €32–72

  7. Fly to Florence Peretola Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Florence Peretola Airport (FLR)plane plane FCO - FLR
    2. Take the train from Firenze S.M.N. to Pisa Centraletrain train
    4h 52m
    €70–215

  8. Fly to Bologna Guglielmo Marconi Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FCO - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Pisa Centraletrain train
    5h 38m
    €67–243

Sistine Chapel to Pisa by foot and train (Trenitalia)

Calendar47Weekly Services
Duration3h 57mAverage Duration
Ticket€20Cheapest Price
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Questions & Answers

What companies run services between Sistine Chapel, Vatican City and Pisa, Italy?

Trenitalia operates a train from Roma S. Pietro to Pisa Centrale every 4 hours. Tickets cost €20–60 and the journey takes 3h 43m. Trenitalia Intercity also services this route twice a week. Alternatively, FlixBus operates a bus from Roma, Autostazione Tiburtina to Pisa 4 times a day. Tickets cost €12–24 and the journey takes 4h 35m.

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