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How to get fromSistine Chapel to Pisaby train (Trenitalia), bus, car, plane, or train

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There are 9 ways to get from Sistine Chapel to Pisa by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train via Civitavecchia (Trenitalia)

    best
    1. Take the train from Roma S. Pietro to Civitavecchiatrain train Re / ...
    2. Take the train from Civitavecchia to Pisa Centraletrain train Fb / ...
    3h 42m
    €34–89

  2. Train (Trenitalia)

    cheapest
    1. Take the train from Roma S. Pietro to Pisa Centraletrain train 4140 / ...
    3h 57m
    €30–70

  3. Bus

    1. Take the bus from Roma, Autostazione Tiburtina to Pisabus bus N548 / ...
    7h 24m
    €32–58

  4. Drive 323.4 km

    1. Drive from Sistine Chapel to Pisacar car 323.4 km
    3h 45m
    €51–73

  5. Fly Fiumicino International Airport to Florence Peretola Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Florence Peretola Airport (FLR)plane plane FCO - FLR
    2. Take the train from Firenze S.M.N. to Pisa Centraletrain train
    4h 40m
    €73–214

  6. Fly Fiumicino International Airport to Pisa International Airport

    1. Fly from Fiumicino International Airport (FCO) to Pisa International Airport (PSA)plane plane FCO - PSA
    4h 50m
    €47–196

  7. Fly Roma Ciampino Airport to Pisa International Airport

    1. Fly from Roma Ciampino Airport (CIA) to Pisa International Airport (PSA)plane plane CIA - PSA
    6h 7m
    €58–252

  8. Fly Fiumicino International Airport to Bologna Guglielmo Marconi Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Bologna Guglielmo Marconi Airport (BLQ)plane plane FCO - BLQ
    2. Take the train from Bologna Centrale to Firenze S.M.N.train train
    3. Take the train from Firenze S.M.N. to Pisa Centraletrain train
    5h 20m
    €60–179

  9. Fly Fiumicino International Airport to Genoa Cristoforo Colombo Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Genoa Cristoforo Colombo Airport (GOA)plane plane FCO - GOA
    2. Take the train from Genova Brignole to Pisa Centraletrain train
    5h 43m
    €64–211

Sistine Chapel to Pisa by foot and train (Trenitalia)

Calendar203Weekly Services
Duration3h 42mAverage Duration
Ticket€34Cheapest Price
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Questions & Answers

Map of how to get from Sistine Chapel to Pisa.ExpandLaunch map view
  • Distance: 320.7 km
  • Duration: 3h 42m

What companies run services between Sistine Chapel, Vatican City and Pisa, Italy?

You can take a vehicle from Sistine Chapel to Pisa Centrale via Roma S. Pietro and Civitavecchia in around 3h 42m. Alternatively, FlixBus operates a bus from Roma, Autostazione Tiburtina to Pisa 3 times a day. Tickets cost €30–50 and the journey takes 5h 30m.

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