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How to get fromSistine Chapel to Milanby train (Trenitalia), bus, car, plane, or train

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There are 5 ways to get from Sistine Chapel to Milan by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Roma Termini to Milano Centraletrain train Fr / ...
    3h 49m
    €72–178
  2. Bus

    cheapest
    1. Take the bus from Rome Tiburtina Largo Mazzoni to Milano, San Donato M3bus bus Bergamo
    9h 24m
    €36–78
  3. Drive 573.2 km

    1. Drive from Sistine Chapel to Milancar car 573.2 km
    5h 21m
    €92–132
  4. Fly

    1. Fly from Fiumicino International Airport (FCO) to Milan Linate Airport (LIN)plane plane FCO - LIN
    3h 24m
    €53–169
  5. Train via Cavalleggeri/Fornaci

    1. Take the train from Roma Termini to Milano Centraletrain train 9950 / ...
    3h 54m
    €72–158

Sistine Chapel to Milan by foot, bus, and train

Calendar93Weekly Services
Duration3h 49mAverage Duration
Ticket€72Cheapest Price
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Questions & Answers

What companies run services between Sistine Chapel, Vatican City and Milan, Italy?

Trenitalia Frecce operates a train from Roma Termini to Milano Centrale every 30 minutes. Tickets cost €80–170 and the journey takes 3h 10m. ItaloTreno also services this route 4 times a day. Alternatively, Itabus S.p.A. operates a bus from Rome Tiburtina Largo Mazzoni to Milano, San Donato M3 once daily. Tickets cost €35–70 and the journey takes 7h 30m.

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