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How to get fromSistine Chapel to Milanby train, bus, car, plane or train (Trenitalia)

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There are 7 ways to get from Sistine Chapel to Milan by train, bus, car, plane, or train (Trenitalia)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Roma Termini to Milano Centraletrain train 9950 / ...
    3h 56m
    €76–107
  2. Bus

    cheapest
    1. Take the bus from Roma, Autostazione Tiburtina to Florence Villa Constanza Bus Stationbus bus 510 / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Milano, San Donato M3bus bus N528 / ...
    9h 6m
    €32–77
  3. Drive 573.1 km

    1. Drive from Sistine Chapel to Milancar car 573.1 km
    5h 21m
    €90–129
  4. Fly to Milan Linate Airport

    1. Fly from Fiumicino International Airport (FCO) to Milan Linate Airport (LIN)plane plane FCO - LIN
    3h 24m
    €51–171
  5. Train via Sistine Chapel

    1. Take the train from Roma Termini to Milano Centraletrain train Fr / ...
    4h
    €72–167
  6. Train via Milan Rogoredo

    1. Take the train from Roma Termini to Milan Rogoredotrain train 9954 / ...
    5h 1m
    €72–96
  7. Fly to Milano Malpensa Airport, train

    1. Fly from Fiumicino International Airport (FCO) to Milano Malpensa Airport (MXP)plane plane FCO - MXP
    2. Take the train from Malpensa Aeroporto T1 to Milano Porta Garibalditrain train
    4h 18m
    €54–134

Sistine Chapel to Milan by foot and bus

Calendar62Weekly Services
Duration9h 6mAverage Duration
Ticket€32Cheapest Price
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Questions & Answers

What companies run services between Sistine Chapel, Vatican City and Milan, Italy?

ItaloTreno operates a train from Roma Termini to Milano Centrale every 30 minutes. Tickets cost €75–100 and the journey takes 3h 5m. Alternatively, you can take a vehicle from Sistine Chapel to Milano, San Donato M3 via Cavalleggeri/Fornaci, Roma, Autostazione Tiburtina, and Florence Villa Constanza Bus Station in around 9h 6m.

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