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How to get fromSistine Chapel to MilanBy train (Trenitalia), bus, car, plane, or train

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There are 5 ways to get from Sistine Chapel to Milan by train (Trenitalia), bus, car, plane, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train

    best
    1. Take the train from Roma Termini to Milano Centraletrain train Fr / ...
    3h 48m
    €72–167
  2. Bus

    cheapest
    1. Take the bus from Roma to Firenzebus bus Roma / ...
    2. Take the bus from Florence Villa Constanza Bus Station to Milano, San Donato M3bus bus N528 / ...
    8h 55m
    €34–77
  3. Drive 573.2 km

    1. Drive from Sistine Chapel to Milancar car 573.2 km
    5h 21m
    €90–129
  4. Fly

    1. Fly from Fiumicino International Airport (FCO) to Milan Linate Airport (LIN)plane plane FCO - LIN
    3h 24m
    €53–159
  5. Train via Cavalleggeri/Fornaci

    1. Take the train from Roma Termini to Milano Centraletrain train 9950 / ...
    3h 52m
    €76–157

Sistine Chapel to Milan by foot, bus, and train

Calendar93Weekly Services
Duration3h 48mAverage Duration
Ticket€72Cheapest Price
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Questions & Answers

What companies run services between Sistine Chapel, Vatican City and Milan, Italy?

Trenitalia Frecce operates a train from Roma Termini to Milano Centrale every 30 minutes. Tickets cost €80–160 and the journey takes 3h 10m. ItaloTreno also services this route 4 times a day. Alternatively, you can take a vehicle from Sistine Chapel to Milano, San Donato M3 via Emo/Bragadin, Roma, and Florence Villa Constanza Bus Station in around 8h 55m.

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