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How to get fromSimpsonville to Pittsburghby plane, bus, bus (Greyhound), taxi, train, car, or bus (Greyhound, Flixbus)

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There are 6 ways to get from Simpsonville to Pittsburgh by plane, bus, bus (Greyhound), taxi, train, car, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Greenville–Spartanburg International Airport, bus

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Pittsburgh International Airport (PIT)plane plane GSP - PIT
    2. Take the bus from Pittsburgh International Airport to Seventh Ave + William Penn Plbus bus
    3h 18m

  2. Drive to Asheville Regional Airport, fly

    cheapest
    1. Drive from Simpsonville to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Pittsburgh International Airport (PIT)plane plane AVL - PIT
    6h 13m
    $76–406

  3. Bus

    1. Take the bus from Taqueria Guadalajara - Greenville to Charlottebus bus
    2. Take the bus from Charlotte Bus Station to Charleston, WVbus bus
    3. Take the bus from Charleston, WV to Cambridgebus bus
    4. Take the bus from Cambridge, OH to Pittsburgh Intermodal Stationbus bus
    16h 57m
    $152–360

  4. Taxi, bus, train

    1. Take the taxi from Simpsonville to Servicios Zapata - Spartanburgtaxi taxi
    2. Take the bus from Servicios Zapata - Spartanburg to Charlottebus bus
    3. Take the train from Charlotte Amtrak Station to Raleigh Union Stationtrain train
    4. Take the train from Raleigh Union Station to Pittsburgh Amtrak Stationtrain train
    22h 44m
    $368–738

  5. Drive 525.2 mi

    1. Drive from Simpsonville to Pittsburghcar car 525.2 mi
    9h 31m
    $96–139

  6. Bus via Washington

    1. Take the bus from Taqueria Guadalajara - Greenville to Charlottebus bus
    2. Take the bus from Charlotte Bus Station to Washington Union Stationbus bus
    3. Take the bus from Washington Union Station to Pittsburgh Intermodal Stationbus bus
    19h 57m
    $182–388

Greenville–Spartanburg International Airport (GSP) to Pittsburgh International Airport (PIT) flights

Calendar67Weekly Planes
Duration3h 35mAverage Duration
Ticket$84Cheapest Price
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Questions & Answers

Map of how to get from Simpsonville to Pittsburgh.ExpandLaunch map view
  • Distance: 440.3 mi
  • Duration: 3h 18m

What companies run services between Simpsonville, SC, USA and Pittsburgh, PA, USA?

You can take a vehicle from Simpsonville to Pittsburgh Intermodal Station via Taqueria Guadalajara - Greenville, Charlotte, Tryon St & Mellow Dr, Transit Center- Bay A, Transit Center- Bay E, 4th St & Graham St, Charlotte Bus Station, Charleston, WV, Cambridge, and Cambridge, OH in around 16h 57m.

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