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How to get fromSimpsonville to Pittsburghby plane, bus, bus (Greyhound), taxi, train, or car

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There are 6 ways to get from Simpsonville to Pittsburgh by plane, bus, bus (Greyhound), taxi, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Greenville–Spartanburg International Airport, bus

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Pittsburgh International Airport (PIT)plane plane GSP - PIT
    2. Take the bus from Pittsburgh International Airport to Seventh Ave + William Penn Plbus bus
    3h 18m

  2. Drive to Asheville Regional Airport, fly

    cheapest
    1. Drive from Simpsonville to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Pittsburgh International Airport (PIT)plane plane AVL - PIT
    6h 14m
    $76–406

  3. Bus via Cambridge

    1. Take the bus from Taqueria Guadalajara - Greenville to Charlottebus bus
    2. Take the bus from Charlotte Bus Station to Charleston Bus Stationbus bus
    3. Take the bus from Charleston, WV to Cambridgebus bus
    4. Take the bus from Cambridge, OH to Pittsburgh Intermodal Stationbus bus
    16h 57m
    $140–345

  4. Taxi, bus, train

    1. Take the taxi from Simpsonville to Servicios Zapata - Spartanburgtaxi taxi
    2. Take the bus from Servicios Zapata - Spartanburg to Charlottebus bus
    3. Take the train from Charlotte Amtrak Station to Raleigh Union Stationtrain train
    4. Take the train from Raleigh Union Station to Pittsburgh Amtrak Stationtrain train
    22h 44m
    $358–738

  5. Drive 525.2 mi

    1. Drive from Simpsonville to Pittsburghcar car 525.2 mi
    9h 31m
    $96–139

  6. Bus

    1. Take the bus from Taqueria Guadalajara - Greenville to Charlottebus bus
    2. Take the bus from Charlotte Bus Station to Charleston Bus Stationbus bus
    3. Take the bus from Charleston to Clarksburg/White Oaks Shelterbus bus
    4. Take the bus from Clarksburg/White Oaks Shelter to Pittsburgh Greyhoundbus bus
    19h 15m
    $130–348

Greenville–Spartanburg International Airport (GSP) to Pittsburgh International Airport (PIT) flights

Calendar60Weekly Planes
Duration3h 37mAverage Duration
Ticket$82Cheapest Price
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Questions & Answers

Map of how to get from Simpsonville to Pittsburgh.ExpandLaunch map view
  • Distance: 440.3 mi
  • Duration: 3h 18m

What companies run services between Simpsonville, SC, USA and Pittsburgh, PA, USA?

You can take a vehicle from Simpsonville to Pittsburgh Intermodal Station via Taqueria Guadalajara - Greenville, Charlotte, Tryon St & Mellow Dr, Transit Center- Bay A, Transit Center- Bay E, 4th St & Graham St, Charlotte Bus Station, Charleston, WV, Cambridge, and Cambridge, OH in around 16h 57m.

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