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How to get fromSimpsonville to Indianapolisby plane, bus (Flixbus), car or bus (Greyhound)

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There are 5 ways to get from Simpsonville to Indianapolis by plane, bus (Flixbus), car, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Greenville–Spartanburg International Airport

    best
    1. Fly from Greenville–Spartanburg International Airport (GSP) to Indianapolis (IND)plane plane GSP - IND
    5h 13m
    $127–593

  2. Drive to Asheville Regional Airport, fly

    cheapest
    1. Drive from Simpsonville to Asheville-Airport-AVLcar car
    2. Fly from Asheville Regional Airport (AVL) to Indianapolis (IND)plane plane AVL - IND
    6h 38m
    $78–428

  3. Bus

    1. Take the bus from Greenville, SC to Atlantabus bus Nyc
    2. Take the bus from Atlanta Bus Station to Indianapolisbus bus FlixBus 2512
    14h 55m
    $128–233

  4. Drive 502.4 mi

    1. Drive from Simpsonville to Indianapoliscar car 502.4 mi
    9h 46m
    $92–133

  5. Bus via Taqueria Guadalajara - Greenville

    1. Take the bus from Taqueria Guadalajara - Greenville to Atlantabus bus Charlotte
    2. Take the bus from Atlanta Bus Station to Indianapolis Union Stationbus bus Greyhound US0100
    18h 24m
    $150–354

Greenville–Spartanburg International Airport (GSP) to Indianapolis (IND) flights

Calendar110Weekly Planes
Duration4h 54mAverage Duration
Ticket$89Cheapest Price
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Questions & Answers

What companies run services between Simpsonville, SC, USA and Indianapolis, IN, USA?

Delta, American Airlines, and two other airlines fly from Greenville–Spartanburg International Airport (GSP) to Indianapolis (IND) hourly. Alternatively, you can take a vehicle from Simpsonville to Indianapolis via Greenville, SC, Atlanta, Buford Hwy @ Mcelroy Rd, Doraville Station, Doraville Station, Garnett Station, and Atlanta Bus Station in around 14h 55m.

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Need to know: Greyhound

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