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How to get fromSilver Spring to Florenceby train (Amtrak), bus (Greyhound, Flixbus), car, plane, bus or train

Find Transport to Florence

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There are 9 ways to get from Silver Spring to Florence by train (Amtrak), bus (Greyhound, Flixbus), car, plane, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Train (Amtrak)

    best
    1. Take the train from Washington Union Station to Florence StationtrainPalmetto / ...
    9h 6m
    $102–264
  2. Bus, train

    cheapest
    1. Take the bus from Washington Union Station to Fayetteville Bus StationbusFlixBus N2471 / ...
    2. Take the train from Fayetteville Amtrak Station to Florence StationtrainPalmetto / ...
    10h 9m
    $67–229
  3. Bus

    1. Take the bus from Washington Union Station to Raleigh Bus StationbusGreyhound US0670 / ...
    2. Take the bus from Raleigh Bus Station to Florence Bus StationbusGreyhound US0642
    9h 53m
    $72–214
  4. Drive 405.7 mi

    1. Drive from Silver Spring to Florencecar405.7 mi
    6h 55m
    $74–107
  5. Fly Ronald Reagan Washington National Airport to Myrtle Beach, bus

    1. Fly from Ronald Reagan Washington National Airport (DCA) to Myrtle Beach (MYR)planeDCA - MYR
    2. Take the bus from Myrtle Beach, SC to Florencebus
    5h 46m
    $129–716
  6. Train to Baltimore-Washington International Airport, fly to Myrtle Beach, bus

    1. Take the train from Washington Union Station to BWI Thurgood Marshalltrain
    2. Fly from Baltimore-Washington International Airport (BWI) to Myrtle Beach (MYR)planeBWI - MYR
    3. Take the bus from Myrtle Beach, SC to Florencebus
    6h 3m
    $149–1,002
  7. Fly Ronald Reagan Washington National Airport to Charlotte Douglas International Airport, bus

    1. Fly from Ronald Reagan Washington National Airport (DCA) to Charlotte Douglas International Airport (CLT)planeDCA - CLT
    2. Take the bus from Charlotte Bus Station to Florence Bus Stationbus
    7h 8m
    $126–649
  8. Fly Ronald Reagan Washington National Airport to Charleston International Airport, train

    1. Fly from Ronald Reagan Washington National Airport (DCA) to Charleston International Airport (CHS)planeDCA - CHS
    2. Take the train from Charleston Amtrak Station to Florence Stationtrain
    8h 8m
    $135–737
  9. Fly Ronald Reagan Washington National Airport to Raleigh-Durham International Airport, bus

    1. Fly from Ronald Reagan Washington National Airport (DCA) to Raleigh-Durham International Airport (RDU)planeDCA - RDU
    2. Take the bus from Raleigh Bus Station to Florence Bus Stationbus
    8h 31m
    $126–713

Silver Spring to Florence by subway and train (Amtrak)

Calendar14Weekly Services
Duration9h 6mAverage Duration
Ticket$102Cheapest Price
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Questions & Answers

What companies run services between Silver Spring, MD, USA and Florence, SC, USA?

Amtrak operates a train from Washington Union Station to Florence Station twice daily. Tickets cost $100–260 and the journey takes 7h 53m. Alternatively, you can take a subway from Silver Spring, Red Line Center Platform to Florence Bus Station via Union Station, Red Line Center Platform, Washington Union Station, and Raleigh Bus Station in around 9h 53m.

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