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How to get fromSikeston to Milwaukeeby bus, taxi, train, car or plane

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There are 9 ways to get from Sikeston to Milwaukee by bus, taxi, train, car, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus

    best
    1. Take the bus from Flying J - Matthews to Water & Chicago - Circle Kbus bus Milwaukee
    9h 19m
    $114–238

  2. Drive 482.9 mi

    cheapest
    1. Drive from Sikeston to Milwaukeecar car 482.9 mi
    8h 6m
    $89–128

  3. Taxi, train (Amtrak)

    1. Take the taxi from Sikeston to Fulton Amtrak Stationtaxi taxi
    2. Take the train from Fulton Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Milwaukeetrain train
    12h 12m
    $250–423

  4. Taxi, bus to Lambert–St. Louis International Airport, fly to General Mitchell International Airport

    1. Take the taxi from Sikeston to Cape Girardeautaxi taxi
    2. Take the bus from Cape Girardeau to St Louis Bus Stationbus bus
    3. Fly from Lambert–St. Louis International Airport (STL) to General Mitchell International Airport (MKE)plane plane STL - MKE
    6h 1m
    $239–1,129

  5. Taxi to Cape Girardeau Municipal Airport, fly to Chicago O'Hare International Airport, train

    1. Take the taxi from Sikeston to Cape Girardeau Municipal Airport (CGI)taxi taxi
    2. Fly from Cape Girardeau Municipal Airport (CGI) to Chicago O'Hare International Airport (ORD)plane plane CGI - ORD
    3. Take the train from Glenview Amtrak Station to Milwaukeetrain train
    5h 50m
    $149–297

  6. Taxi to Cape Girardeau Municipal Airport, fly to General Mitchell International Airport

    1. Take the taxi from Sikeston to Cape Girardeau Municipal Airport (CGI)taxi taxi
    2. Fly from Cape Girardeau Municipal Airport (CGI) to General Mitchell International Airport (MKE)plane plane CGI - MKE
    5h 24m
    $334–1,287

  7. Taxi to Barkley Regional Airport, fly to Chicago O'Hare International Airport, train

    1. Take the taxi from Sikeston to Barkley Regional Airport (PAH)taxi taxi
    2. Fly from Barkley Regional Airport (PAH) to Chicago O'Hare International Airport (ORD)plane plane PAH - ORD
    3. Take the train from Glenview Amtrak Station to Milwaukeetrain train
    6h 30m
    $323–790

  8. Taxi, bus to Nashville, fly to General Mitchell International Airport

    1. Take the taxi from Sikeston to Paducah Bus Stationtaxi taxi
    2. Take the bus from Paducah Bus Station to Nashville Bus Stationbus bus
    3. Fly from Nashville (BNA) to General Mitchell International Airport (MKE)plane plane BNA - MKE
    7h 48m
    $414–682

  9. Bus to Williamson County Regional Airport, fly to Chicago O'Hare International Airport, train

    1. Take the bus from Flying J - Matthews to Marathon Gas Station - Marionbus bus
    2. Fly from Williamson County Regional Airport (MWA) to Chicago O'Hare International Airport (ORD)plane plane MWA - ORD
    3. Take the train from Glenview Amtrak Station to Milwaukeetrain train
    8h 1m
    $141–392

Lambert–St. Louis International Airport (STL) to General Mitchell International Airport (MKE) flights

Calendar23Weekly Planes
Duration1h 34mAverage Duration
Ticket$144Cheapest Price
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Questions & Answers

What companies run services between Sikeston, MO, USA and Milwaukee, WI, USA?

Tornado Bus Company operates a bus from Flying J - Matthews to Water & Chicago - Circle K once daily. Tickets cost $90–210 and the journey takes 9h 5m.

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